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Acarbose

Acarbose is a medicine that helps to control high blood glucose levels. It helps to slow down the breaking down of food in our intestine to simple glucose, thereby decreasing the rise in blood glucose levels after meals.

Other names for this medication:
Abacus, Acarb, Acarbose, Acarex, Acarwin, Acraz, Asucrose, Diabose, Discarb, Disorb, Exforge, Glubose, Glucar, Glucarb, Glucobay, Glucobose, Gludase, Hebose, Olcarbos, Prandase, Rebose, Recarb, Subase, Zebay, Zebose

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Description

Generic Acarbose is used for treating type 2 diabetes in adults whose diabetes cannot be managed with diet alone. Generic Acarbose may be used alone, in combination with other oral diabetes medicines, or with insulin. Generic Acarbose is a glucosidase inhibitor. It works by slowing down the enzyme that turns carbohydrates into glucose; it decreases blood sugar levels following a meal. Acarbose is also known as Acarbose, Glucobay, Glucor, Rebose. Generic name of Generic Acarbose is Acarbose. Brand name of Generic Acarbose is Acarbose.

Dosage

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Acarbose with the first bite of a main meal, unless your doctor tells you otherwise.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

If you take Acarbose with insulin or other diabetes medications, your blood sugar could get too low.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of dextrose (D-glucose) with you in case you have low blood sugar. When taking Acarbose, dextrose will work better than cane sugar or table sugar in treating hypoglycemia. Sources of dextrose include honey, dates, raisins, plums, dried prunes, grapes, or glucose tablets. Be sure your family and close friends know how to help you in an emergency.

If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice.

Acarbose is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Acarbose dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

In case of overdose, do not eat or drink anything containing carbohydrates for the next 4 to 6 hours.

Storage

Store at room temperature below 25 degrees C (77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acarbose are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Acarbose if you are allergic to Generic Acarbose components. Be careful with Generic Acarbose if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Generic Acarbose if you have blockage of the stomach or intestine or are at risk for these problems. Do not take Generic Acarbose if you have long-term (chronic) bowel inflammation, colon ulcers, or stomach or intestine problems that interfere with digestion or nutrient absorption. Do not take Generic Acarbose if you have cirrhosis of the liver or unexplained abnormal liver function tests. Do not take Generic Acarbose if you have diabetic ketoacidosis (high ketone levels) or severe kidney problems. Try to be careful with Generic Acarbose if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Try to be careful with Generic Acarbose if you have allergies to medicines, foods, or other substances if you have stomach or intestinal problems, liver problems, or kidney problems. Try to be careful with Generic Acarbose if you are taking anticoagulants (eg, warfarin) because the risk of their side effects, including bleeding, may be increased by Generic Acarbose; calcium channel blockers (eg, verapamil), corticosteroids (eg, prednisone), diuretics (eg, hydrochlorothiazide), estrogen, isoniazid, nicotinic acid, oral contraceptives (birth control pills), phenothiazines (eg, chlorpromazine), phenytoin, sympathomimetics (eg, pseudoephedrine), or thyroid hormone because they may increase or decrease Acarbose 's effectiveness; insulin or sulfonylureas (eg, glyburide) because the risk of their side effects may be increased by Generic Acarbose; digoxin because its effectiveness may be decreased by Generic Acarbose. Avoid alcohol. Do not stop taking Generic Acarbose suddenly.

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The bisbenzamidoxime derivatives of three direct pentamidine analogs had excellent oral and intravenous activities and reduced acute host toxicity. For maximizing treatment effectiveness and minimizing transmission, we recommend educating leprosy patients at treatment completion for self-monitoring of signs of relapse and advising them to visit nearby public health facilities or Community health workers for immediate evaluation and intervention. GroE specifically inhibits the aggregation reaction that competes with correct folding, as shown by a strong decrease in the intensity of light scattering. The ovarian cycle number of ovules and ovarian follicles, insemination, number of embryos, fetal development and the observed malformation were evaluated. The aim of the study was to determine whether accumulation of peroxidized lipoproteins in arterial walls, a process postulated to play a role in initiating atherosclerotic changes, can be demonstrated by fluorescence spectroscopy. Significant anterior displacements of the thorax were observed and were statistically associated with lateral displacements of the spine and with an increase of spinal thoracic curvatures in the frontal and sagittal planes. Pressures before and after laser treatment were measured to determine pressure difference in 15 patients receiving laser treatment. Circulatory arrest is frequently used in aortic arch reconstruction in pediatric cardiac surgery. Therefore, in a highly coordinated manner, CCK regulates the ingestion, digestion, and absorption of nutrients.

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Deletion of a single amino acid changes the folding of an apamin hybrid sequence peptide to that of endothelin. Revival of heparin therapy (role of calcium heparinate administered intracutaneously. In a test-retest reliability study involving 25 psychiatric patients and 5 professional raters we demonstrate that research clinicians from collaborating institutions are able to achieve good reliability for most areas of the SADS and RDC when assessing psychiatrically ill patients under interview conditions that provide even less data than ideally obtained in the practice of clinical research. Matrix metalloproteinase 11 might be a genetic factor in young-middle aged patients. In fused somites mutants, zisp is expressed throughout the somitic mesoderm. TPS2 contains the higher content of uronic acid, but TPS1 contains the higher contents of neutral sugar and protein. IL-10, originally described as a cytokine synthesis inhibitory factor, is secreted by a number of cells of the immune system, including monocytes and T cells. Anaphylactoid reaction to hydroxyethylstarch during cesarean delivery in a patient with HELLP syndrome. The excretion of peptides increased compared with that in an age- and sex-matched reference group.

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Elemental alterations in the nucleus and mitochondria were similar to those in the cytoplasm in both the control and TAK-044 groups. In a sample of 236 healthy Hungarian adults, we found that CC homozygotes report higher flow proneness than do T allele carriers, but only during mandatory activities (i.e., studying and working), not during leisure time. CHRNA4 is highly expressed in the central nervous system and has been demonstrated to be significantly associated with schizophrenia by previous studies. In contrast, there were no differences in the number of subjects who showed expression of IFN-gamma mRNA, or in mean density ratios for IFN-gamma between the two groups. These Fab fragments were subsequently screened for an effect on HGF/SF activity either as monomeric fragments or after dimerization with a monoclonal antibody (9E10) directed against a peptide tag on the fragments. A spacer between this basic domain and NLS I is necessary for the entrance of p53 into the cell nucleus. Monitoring of microflora localized at the pharyngeal tonsil surface in the children residing in the city of Chelyabinsk and presenting with chronic adenoiditis. To provide information about the effect of autonomic dysfunction on P-wave dispersion, as a predictor of atrial fibrillation, in patients with spinal cord injury.

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In the other three models the distribution of Q(B) between the proximal position and the distal position was pH-independent, with Q(B) occupying only the distal position or only the proximal position or populating the two positions with a fixed ratio. Plasma fibronectin has a high affinity for denatured collagen (gelatin) and exerts an opsonic influence on phagocytosis of test colloids and clearance of tissue debris by macrophages. The search strategy was expanded and modified to include manuscripts of any study design that comprise both inlier and outlier patients. In some patients with cancer the condition is resistant to warfarin, and long-term adjusted high-dose heparin is required. Prophylactic administration of dexamethasone is effective in reducing PONV in patients with and without a history of motion sickness.

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The use of offspring sex ratios to detect reproductive effects of male exposure to dioxins. To determine how the mammalian endocycle is regulated, we examined the expression of the cyclins and cyclin-dependent kinases during the transition from replication to endoreduplication in the Rcho-1 rat choriocarcinoma cell line. Although pathomorphological findings of the early postablative period are well documented in animals, only few data are available on pathological postablative changes in humans. The response of tumor cell cultures suggests that pregnancy-independent mouse mammary epithelium may not be entirely refractory to prolactin. We studied the influence of reperfusion on carrier and barrier functions of the blood-brain barrier after transient global ischemia in rats. We report five cases of BCC arising in venous ulcers of the lower extremity that we have observed over a period of 6 years. Condition of ocular blood supply in patients with primary open-angle glaucoma with normal pressure. Genetic and antigenic diversity of Ehrlichia chaffeensis: comparative analysis of a novel human strain from Oklahoma and previously isolated strains. Only about one half of mothers were able to perform regular breast feeding.

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Tattoo formation from absorbable synthetic suture and successful removal with Q-switched ruby laser. Acute hepatitis in a patient using a Chinese herbal tea--a case report. Children with HIV/AIDS and their families: a successful social work intervention based on the culturally specific health care model. UL84 is essential for replication of a cloned viral origin of lytic replication (oriLyt) in vitro and mutants of strains AD169 or Towne with deletions or insertions in UL84 fail to grow in cells permissive for wild type virus. Previous studies have shown that Rap1p, which binds to the double-stranded telomeric repeats, plays a role in regulating repeat length: point mutations in the Rap1p C-terminus often result in a higher average telomere length and deletion of this region causes extreme telomere elongation. When an individual develops statements about attitude or needs, he or she uses social information--information about past behavior and about what others think. We analyse patients with PM who have been operated between 1976-1996. To study emotional status, including alexithymia, anxiety and depression, in patients with cerebral infarction in the area of the middle cerebral artery (on the left side) in the late recovery period and to develop a method for correction of the damage. Enhanced fibrinolysis observed was countered by elevated plasminogen activator inhibitor-I (PAI-1) levels, a trend similar to that observed in the amniotic fluid during labour.

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We conducted a retrospective cohort study comparing exposed women (endometriosis) and control (without endometriosis) regarding the incidence of miscarriages. Knowledge of methods used in the diagnosis of states of tear deficiency will allow the surgeon to better select candidates for cosmetic eyelid procedures. Recently, there has been significant progress in our understanding of the interactions responsible for helix stability in monomeric peptides and this information has been included in algorithms based on the helix/coil transition theory. After a minimum of two years of follow-up, we could detect no significant differences, with the numbers available, between the two groups with regard to the functional result or the degree of joint laxity that was evident on stress radiographs. While antibiotics are often prescribed for patients with acute bronchitis, little evidence shows that these agents provide significant symptomatic relief or shorten the course of the illness. During the follow-up period, 12 tumors decreased in size, whereas there was no change in eight tumors, and in one tumor imaging follow-up was not available. The diagnosis of scar endometriosis is usually not difficult and is based on history and physical examination. The vac A genotype of each isolate was determined by polymerase chain reaction (PCR) amplification of genomic DNA for specific regions of the vac A gene. Following a random scheme, a group of ten patients was treated with conventional cimetidine and a group of ten with cimetidine of sustained release.

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Treatment of complications of psychiatric diseases by medical psychiatry. The Levels of Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury: Correlations With Clinical and Imaging Findings. Although stage is the most powerful predictor of long-term survival, it remains unclear whether other factors influence prognosis. Prognosis is poor in patients in whom residual malignant germ cell tumour persists in spite of conventional cisplatin-based induction chemotherapy, especially in patients who initially present with large or very large volume disease and/or pre-operatively elevated tumour markers. A multidrug efflux pump designated LmrS (lincomycin resistance protein of Staphylococcus aureus), belonging to the major facilitator superfamily (MFS) of transporters, was cloned, and the role of LmrS in antimicrobial efflux was evaluated.

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Few practitioners follow American Academy of Pediatrics guidelines in selection of HP candidates. These results suggest that the enhanced cytotoxicity seen with the combination of TNF-alpha and DOXO is not the result of any modulation of drug influx or efflux levels by TNF-alpha. Results of scanner performance tests are presented, which demonstrate that the latest pCT scanner approaches readiness for clinical applications in hadron therapy. Biochemical analyses, using competition binding assays with a synthetic peptide containing the 15 aa between aa 304 and aa 318 (NSGNGAVEDRKPSGL), further support the conclusion that this region contains the ankyrin-binding domain of CD44s. Prognostic significance of precordial ST-segment changes in acute inferior wall myocardial infarction. Modeling and mentoring: critical elements of a successful career.

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Radiometals have become increasingly important because of their use both for diagnostic molecular imaging and therapy in Nuclear Medicine. Influenza vaccination has substantial clinical effectiveness in preventing hospital admission and death from influenza-associated conditions in noninstitutionalized individuals. Marine restoration ecology is a young scientific discipline, often with gaps between its application and the supporting science. For a large majority of those patients, their social functioning seems enriched and more differentiated. Knottin scaffolds therefore appear to be a promising architecture for the creation of small folded proteins with binding activities, with the potential for improvement of binding affinities by mutation, or glucophage of using other faces of the protein to provide greater structural diversity in the primary repertoire. Microvascular surgery in the reconstruction of congenital hand anomalies. However, these events could be caused by limited number of tested patients. The retinal projection to the basal telencephalon was studied in eight species of primates from the suborders Strepsirhini and Haplorhini, including one anthropoid primate, the gibbon. These feelings probably reflect decreased activity of the hypothalamic-pituitary-adrenal axis. We determined that that only PVN- and CeA-injected PHI did not have aversive consequences.

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VDAC1 protein levels in the uterus also correlated well with the apoptotic index of the luminal epithelium. Intima flap of the external carotid and postoperative stroke in a patient surgically treated with thromboendarterectomy of the internal carotid. This selection enabled the detection of five different mutations in the cloned CYP51A1 genes which correlated with the occurrence of azole resistance in clinical C. Specifically, we suggest that acute depressions are characterized by hypersecretion of hypothalamic corticotropin-releasing factor, pituitary adrenocorticotropic hormone (ACTH), and ultram 100 mg time released adrenal cortisol. An optimal method can be chosen to treat every case of infection and partial rupture of the expanded postauricular flap. Various immunoblot and enzyme-linked immunosorbent assays showed both IgG and IgA antibodies to various autoantigens, including desmogleins, desmocollins, envoplakin, periplakin and bullous pemphigoid antigens. Serum or plasma samples collected on the day before the operation, at the time of skin closure, and on postoperative days 1, 3, 5, and 7. The excitatory effects of the amygdala on hypothalamo-pituitary-adrenocortical responses are mediated by hypothalamic norepinephrine, serotonin, and CRF-41. DNA fragments of 121, 517, 968 and 1578 bp, each possessing a known point mutation, were generated by polymerase chain reaction (PCR).

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Evaluation of tissue injury induced by chemicals is crucial to drug development. We also demonstrate that NS5B form a complex with NS4A in the absence of NS3. Personalized medicine: potential impact on the biopharmaceutical industry. In some cases, the diagnosis of Whipple disease is uncertain if it is based on histology alone. Changes in plasma levels of lipids and lipoprotein composition in patients with Kawasaki disease. All patients responded to a course of topical steroids and oral ibuprofen or prednisone. In five of six cases the lumen was narrowed, from slight accentuation of the haustrum to almost pinhole-like concentric stenosis.

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It is necessary to study further syndrome differentiation based treatment of peripheral vascular disease. Female circumcision/genital mutilation: culturally sensitive care. Male Fischer 344 rats, 6 weeks of age, were administered single i.p. Semianalytical approach to study the loss characteristics of a symmetrical multilayered plasmonic waveguide. Incidence of spondylolisthesis in ambulatory cerebral palsy patients. For acoustic measurements, the five Japanese vowels and Japanese conversational sentences were recorded and analyzed. Human cytomegalovirus (HCMV) has evolved a multitude of molecular mechanisms to evade the antiviral immune defense of the host. Comparison of the genotyping results based on core-envelope 1 and non-structural 5B sequence phylogenetic analyses to detect the possible recombinants.

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The ODAO method clearly outperforms both reference methods in terms of classification accuracy (in training and validation samples), robustness to outliers, simplicity of use and applicability in clinical settings. Several epidemiological and experimental studies have associated the intake of antioxidants, which are abundant in the Mediterranean diet, with a low incidence of cardiovascular disease. The deviceimproves the light transmission of a high-resolution spectrograph by an (unprecedented) order of magnitude. This seems to have a general bearing on comparisons between groups of the same age but with different years of birth. Importantly, the nuclear CDK2 activity which is crucial for G(1)/S transition is not altered by p27(Kip1) increase. Our data indicate that the use of CD/5-FCyt in combination with IFNs may provide a more effective approach for the treatment of brain tumors. Low SCC of milk from cows in late lactation may have minimized the changes in cheese composition and yield from stage of lactation. It is not known whether flupenthixol decanoate is of value in the prophylactic treatment of recurrent manic-depressive illness, but the drug may be worth trying in patients whose disease is dominated more by manic than by depressive recurrences and who do not respond to lithium or do not tolerate it or do not take it. To present a comprehensive account and literature review addressing the anatomical distribution, plaquenil cost per dose natural history, and management strategies for locoregional recurrence in early-stage gastric cancer (EGC).

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Membrane ATPase from the aceticlastic methanogen Methanothrix thermophila. An unusual form of adenoma of left lobe of liver was detected fortuitously in a young woman with an inflammatory syndrome and an anicteric cholestasis. To provide a tool for further physiological and pharmacological studies monolayer cell cultures of human scleral spur have been established and characterized. The densities of SSRs across the human chromosomes were found to be relatively uniform. The use of topical estrogen resulted in a separation of the fused labia in approximately half diamox dosage ich of patients. The results of this study suggest prolonged reduction of norepinephrine uptake and storage capacity in the cardiac sympathetic nerve terminals which may reflect the effect of repetitive elevation of norepinephrine levels induced by cocaine exposure. TC resulted in an acute but more rapidly declining effect on soil microbiome while CIP and SMM led to a delayed antibiotic effect. Gametophytic and sporophytic expression of an anther-specific Arabidopsis thaliana gene. These overviews should provide reliable data about the effects of newer classes of blood-pressure-lowering drugs (such as angiotensin converting enzyme inhibitors and calcium antagonists) on major causes of cardiovascular mortality and morbidity for a variety of patient groups. Here we provide evidence that the second open reading frame encodes a replication protein (Rep).

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