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Acnex (Methylprednisolone)

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Acnex is a corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. Acnex is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.

Other names for this medication:
Acnex, Avpred, Cartipred, Hysone, Meprolone, Methylprednisolone, Predon, Prelonb, Sterid, Zempred, Zencort

Similar Products:
Differin, Moduretic, Provera, Astelin, Clarinex, Atenova, Lipex, Liponorm, Asart, Loten, Melife, Typteez, Suprasulf,

Also known as: Methylprednisolone


Methylprednisolone injection provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, eye or vision problems, lupus, skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis. Methylprednisolone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

This medicine is to be given only by or under the direct supervision of your doctor.


This section provides information on the proper use of a number of products that contain methylprednisolone. It may not be specific to Depo-Acnex. Please read with care.

A nurse or other trained health professional will give you this medicine. It may be given through a needle placed into one of your veins, as a shot into a muscle or joint, or as a shot into a lesion on your skin.

Your doctor may give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Depo-Acnex dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of methylprednisolone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Store at room temperature between 15 and 30 degrees C (59 to 86 degrees F) away from moisture and heat. Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acnex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Trimetazidine prevents cochlear lesions induced by intraperitoneal and perilymphatic administration of kainic acid. The fourth AACR Special Conference on The Role of Telomeres and Telomerase in Cancer Research was held February 27 to March 2, 2010 in Fort Worth, TX. Characterization of the effects of HIV-1 infection and apoptosis on cellular and viral gene expression. Here, we review the postulated modes of action of somatostatin and somatostatin-like peptides, including the currently available synthetic somatostatin analogs, in cells of the immune system. It is presented a discussion for separating the new genus from Diachlorini species which resemblance with sarcophagids flies. (2) To examine MMP activity in wounded corneal epithelium in diabetic rats. Primary repair of bilateral incomplete cleft lip appears to be uncomplicated but requires attention to technical details in the third dimension in anticipation of changes in the fourth dimension.

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High grade squamous intraepithelial lesion (HSIL) of the cervix is well known to be associated with human papillomavirus (HPV) infection. To explore virtual reality (VR) as a distraction intervention to relieve symptom distress in adults receiving chemotherapy treatments for breast, colon, and lung cancer. This indicates that there may be a role of induction chemotherapy in converting potentially unresectable tumors to resectable disease that could produce better outcomes in carcinoma EAC. Fluorescent urine has been reported to indicate antifreeze ingestion. Choice-supportive source monitoring: do our decisions seem better to us as we age?. The majority of patients operated on for mitral valve disease with chronic atrial fibrillation (AF) do not recover sinus rhythm with conventional postoperative treatment. Because enlargement of the parathyroid glands has important implications for disease progression and disease severity, it is possible that clinical management strategies that maintain adequate calcium-dependent signaling through the CaSR will ultimately prove useful in diminishing parathyroid gland hyperplasia and in modifying disease progression. Two case patients with a history of hemiplegic migraine with prolonged auras are presented, who both had complete alleviation of their aura symptoms with GON blockade. When sensory inputs are lost, and are later illusorily regained, the brain updates a coherent body image even several years after the body has become permanently unable to feel.

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In this study, we examined the ability of two antioxidants, vitamin E and probucol, to reduce lipid peroxidation in vivo and renal hypertrophy, an early stage of diabetic nephropathy, in rats. Affective facial expression processing in young children who have experienced maltreatment during the first year of life: an event-related potential study. Author misconduct: What journal editors do when they suspect and find it?. Taxol plus RT led to cell survival of 0.00025/0.0014/0.042 (1 hour) and 0.0004/0.0019/0.04 (9 hours) without significant difference between chosen time intervals. A draining vein connecting to the hepatic vein may be a characteristic of focal nodular hyperplasia. In 2 cases we did not find a rupture of the quadriceps tendons ultrasonographically. The objective of this analysis is to evaluate the association between measures of body size, dietary macronutrient intake, and reproductive factors with levels of endogenous sex hormones among women living in Shanghai, China. In contrast, these populations were the predominant sources of IFN-gamma, as determined by lack of detectable IFN-gamma production in NK and T cell-deficient mice and by intracellular cytokine expression in the cell subsets. Retinal detachment caused by laser coagulation of the fundus oculi. Nitration mainly depended on the total amount of tyrosine residues as well as on surface exposition.

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The authors reported their results of BCG immunotherapy in the treatment of the bladder cancer. Infusing 31.5 ml/h isotonic solution, 20 micrograms/kg/min Fenoterol and 3.125 micrograms/kg/min Metoprolol, excretion, creatinine clearance, electrolyte elimination, the serum electrolyte levels, Hb, HK and the weight were determined. We are then able to easily interpret the related hidden groups as healthy, sick, and terminally ill subjects. Despite effective immunosuppression and anticoagulation her initially mild precapillary pulmonary hypertension progressed in the absence of thromboembolic events, cardiopulmonary disease or other systemic disorders. Furthermore, our records show that the observed covariation between atmospheric CO2 concentration and abyssal Southern Ocean oxygenation was maintained throughout most of the past 80,000 years. Reducing central serotonin in adulthood promotes hippocampal neurogenesis. Leucine codons of uridyl-uridyl-adenine (UUA) and uridyl-uridyl-guanine (UUG) are synthesized by the triester method. The combination of bursectomy and flucytosine treatment cured the infection. Small individuals had higher concentrations of Fe and Ni than larger individuals.

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Diazepam and levamisole restored the decrease of humoral immune responses. A surgical resection of the SP was performed on the former patient. This is accompanied by the appearance of morphologically altered cells which express several specific markers characteristic of differentiated cells, suggesting that c-fos plays a role in cellular differentiation. The additional value of serum ECP concentrations and eosinophil counts to detect an asthmatic constitution for individual cases is doubtful. Cry1F inhibited (125)I-Cry1Ab binding at concentrations greater than 500 nM. We hypothesized that multidrug resistance protein 4/ATP binding cassette transporter 4 (MRP4/ABCC4), a widely expressed transporter of nucleoside-based antiviral medications as well as cancer therapeutics might interact with PIs. Optimization of the deformation geometry allows for a 3.6-fold increase in intensity for a far-field detector. Patients with hiatal hernia, esophageal diverticulum, or vigorous achalasia may safely undergo progressive pneumatic dilation. In patients with mild hypertension the blood pressure reduction through n-3 fatty acids can be improved by an additional increase of the potassium intake.

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The cleavage of peptide bonds at amino acid residues E22 or/and V25 caused weaker subunit interactions and partial dissociation of the alpha- and gamma-subunits. Death receptor induced apoptosis: a new mechanism of homocysteine-mediated endothelial cell cytotoxicity. Interestingly, these OprM suppressor mutations restored multidrug resistance in P. This study assessed the comparative safety and efficacy of these two stents in unrestricted contemporary real-world practice. In this system it was found that disruption of either half or all of the neutrophils in the samples markedly improved the ability of the cells to handle an inoculum of Candida yeast cells over a 48-h period, even though the disrupted cells had primarily candidastatic activity, with very little candidacidal activity. We found that the mutual influence among neuronal groups depends on the phase relation between rhythmic activities within the groups. Trends in hypertension prevalence and management in Southwestern France, 1985-1996.

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The aim of this study was to evaluate the correlation between BWT and the International Prostatic Symptom Score (IPSS) in patients with benign prostatic hyperplasia (BPH) before and after tamsulosin treatment. In addition, we identify other areas that need development, and how modelling might usefully contribute to these areas of reproduction science. Using handheld computers, 33 women with bulimic syndromes provided ongoing self-reports on eating behaviors, affects, and dissociative experiences over 7- to 29-day intervals. Because abortion is not involved, and multiple embryos are available, PID is radically more effective as a tool of genetic selection. Two demographically similar areas in Nottingham, one served by a specialist home care team, the other by standard services. Re-infusion of ascitic fluid with high protein content in cirrhosis patients. Incidental (malignancy) and coincidental (idiopathic polydactylous longitudinal erythronychia) conditions in patients with segmental neurofibromatosis. Here we demonstrate that, until recently, virulent viruses from genotype V continued to circulate and evolve in the country. Increased duration in clinical practice, the number of scans clinically interpreted in practice, and level 3 competency were associated with higher passing rates. The collagen experiments were designed to investigate the intermolecular interactions between molecules in collagen fibres.

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Administrative datasets can provide important information on demographic gaps in care for patients with SCD. The differences in the effect of homoeopathic and electronic D8 on uricase were found to be statistically relevant. TO with or without TR caused lung growth with normalization of lung parenchymal architecture and type II cell density. The pathway to substance dependence is complex and involves multiple genetic and environmental risk factors. The results indicate that histamine is present in several neurons and/or nerve fibers of all major ganglia.

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This new model of empathy describes a complex and dynamic process and conceptualizes ideal conditions for empathic treatment. This article describes the development and teaching strategies of a successful university-based graduate breastfeeding Internet course. Results suggest that although odontoclastic resorption lesions are common in cats, pulpal involvement associated with these lesions does not appear to be associated with development of radiographically detectable periapical lucencies. Finally, the value of the quantitative parameters derived from functional MR and (18)F-FDG PET/CT imaging as prognostic markers in the prediction of treatment outcome will also be discussed. In another condition, participants made the same arm movements while observing a real human. However, differences in the side effect of weight gain may be even more relevant in bipolar disorder than in schizophrenia due to the need to use standard mood stabilizers that often potentiate such weight gain. Increased urinary albumin excretion was defined according to the ACR ranges greater or equal than 30 mg/g. Three hundred male heads of family were interviewed from three municipalities in the Isthmus of Tehuantepec, Oaxaca, Mexico selected to span a wide range of cultural change. For three patients who were above average users of the prosthesis, pitch increased with frequency over a smaller range (100 Hz to 1200-2300 Hz).

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A functional scheme is advanced showing how selector genes may become activated and control development. Initial IDET case series from single practices have reported improved pain, function, and return to work outcomes. SA-induced Hsp17.6 expression had a different dose-response to PR-1 expression. From the theory of formal systems we know that any theory with contradictory principles explains everything and so explains very little. Near-infrared fluorescent proteins (FPs) are in high demand for in vivo imaging. Heterozygosity was significantly lower than expected under random mating and lower than that found in other spider monkey populations, possibly reflecting a recent decline in genetic diversity and a threat from inbreeding. This review attempts to dispel these myths and compares and contrasts the risks of enteral nutrition with those of parenteral nutrition in the critically ill. Information about disability pensions was obtained from Statistics Denmark. We constructed a synchrotron radiation X-ray microscope for sequential tomography of mouse tibia first by using a Talbot interferometer to detect the degree of bone mineralization and then by using absorption contrast under a slightly defocused setting to enhance outline contrast thereby visualizing structures of the osteocyte lacuno-canalicular network. Regardless of the strategies implemented in the name of managing care, the evolving health care environment has changed where and how nurses practice.

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Cyclops syndrome: loss of extension following intra-articular anterior cruciate ligament reconstruction. However, patients with comorbidities are at a high risk of poor prognosis. These results demonstrate the potential of the method to provide a practical solution to the problems of TSE contamination of surgical instruments and highlight the inadequacy of using Western blot for assessment of decontamination/inactivation of TSE agents. Furthermore, medical experience regarding prolonged somatic support is limited. This is the first time that data have been obtained on intracellular concentrations of d4T-TP and ddA-TP, their intracellular pharmacokinetics and interpatient variability. The most common symptoms are weight loss and diarrhea, preceded in three quarters of cases by arthritis for a mean of 6 years. The dog had previously been prescribed antimicrobials and antifungal treatment, but owner compliance was lacking. Power Doppler ultrasonography of the feeding arteries of the prostate gland: a novel approach to the diagnosis of prostate cancer?. We then worked out values for the rate constant for the surface pause before using this constant to examine bird body oxygen levels immediately pre- and post dive.

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Loss in membrane integrity altered the activities of the tricarboxylic acid cycle enzymes and levels of cytochromes. The widespread use of thyroid tests in asymptomatic individuals identifies many patients with transient subclinical hypothyroidism. Government urged to pay more than lip service to health education. The diurnal variation of corticosterone and the response of corticosterone to corticotropin-releasing factor were not significantly different between genotypes. The Z-disk lattice spacing, z, was measured in electron micrographs of thin sections from the same muscles. Measures included anthropometrics (weight and height), physical activity (pedometer and International Physical Activity Questionnaire), questionnaires (risk perception), and GDM screening. SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. The results suggest that better health care accessibility in urban areas persists when taking a holistic view. The gamma-3 gene is adjacent to a marker for a convulsive disorder. The CESA1 component of cellulose synthase is phosphorylated at sites clustered in two hypervariable regions of the protein.

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The multi-locus analysis, applied in a genomic window, enables local inference of the QTL genetic architecture and is an alternative to imputation. Epithelial tissues function to protect the organism from physical, chemical, and microbial damage and are essential for survival. Such a task cannot be successfully resolved by traditional approaches. VR and exergaming technology have been primarily investigated in post-CVA rehabilitation, however, more recent work has shown this type of biofeedback to be effective in improving exercise technique in musculoskeletal populations. The objective of this study was elavil 10 mg pour dormir to evaluate whether the post-neonatal hospitalization and resulting health care costs are increased among in vitro fertilization (IVF) children up to 7 years of age. Approaches taken to the treatment of young children with carious primary teeth: a national cross-sectional survey of general dental practitioners and paediatric specialists in England.

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This is the first report of prenatal diagnosis of a terminal 14q deletion. This report presents the chronology of the addiction problem from childhood as well as evidence of significant early antisocial activities predating drug use in this population. Pharmacokinetics and MR imaging of SPIO-shRNA dual functional molecular probe in vivo. This was a retrospective epidemiological study of incident reports originally collected by Paul Caffyn for the Kiwi Association of Sea Kayakers (KASK). Ophthalmic disorders are still too frequent and temporal arteritis remains the first cause of vascular blindness in the elderly. Pituitary dysfunction, present months or years after injury, is now well recognised in adults, however, little evidence is known about this potential complication in children and adolescents.

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Adaptive cytoprotection induced by pretreatment with ethanol protects against gastric cell damage by NSAIDs. Differences between the regulation of cholesterol side-chain cleavage in Leydig cells from mice and rats. The age-standardized mortality rates among the males increased from 1.14 per 100,000 person--years in 1952 to 1.84 in 1991, whereas the corresponding rate among females changed little over the same period. This study uses thin-film pressure sensors to obtain stresses in the medial and lateral compartments of lozol reviews cadaver knees compressed to physiological relevant levels of loading. This large, prospective, nationwide study confirmed plerixafor efficacy for mobilizing PBSCs when added to G-CSF with or without chemotherapy. We evaluated the effectiveness of radiofrequency (RF) ablation combined with transarterial embolization using Lipiodol and gelatin sponge. Silent virulence genes (cyl or gelE) were frequently detected, therefore both the genotypic and phenotypic assays seem necessary for a better characterization of the strains.

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The relationship between blood survivin and VEGF mRNA levels and patients clinicopathologic parameters and prognostic factors were investigated. Cytotoxic activity of NK cells in the presence of the peritoneal fluid fro women with unexplained infertility periactin medicine and with endometriosis related infertility. Pituitary-derived prolactin (PRL) is a well-known regulator of the lactating mammary gland. No statistical differences in group performance between the 250 and 807 pps/ch rates were observed in any of the speech perception tests. All blood samples from calves were negative for BVDV prior to the spiking with the virus. We tested whether antibodies, binding to Galalpha1-3Gal epitopes in porcine tissue, initiate this phenomenon. The muscles of mdx mice express normal amounts of mRNA for the DAPC components, thus suggesting post-transcriptional regulation.

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SPP-induced HUVEC migration is potently inhibited by antisense phosphothioate oligonucleotides against EDG-1 as well as EDG-3 receptors. Previous studies demonstrate that the delta-like (dlk) and preadipocyte factor 1 (Pref-1) genes encode similar proteins. To draw up a scientifically-grounded classification of and terminology for the chamber-type disinfection equipment a classificational scheme of notions has been worked out, the most essential characteristics were laid at its basis, such as operational conditions, the shape of the working chamber, the method of charging and disinfection, as well cozaar 50 mg dose as heating the chamber. The relationship between chloroquine resistance and the recently described multidrug resistance gene is explored and the possibility that this is the main cause of chloroquine resistance by the parasite is discussed. This fingerprint was then analyzed by searching the Mascot and National Institutes of Health BLAST (basic local alignment search tool) databases to determine protein identification. Consistent with prior research, the majority of respondents had not considered relocation to a retirement village. Early onset of smoking is associated with subsequent abuse of other substances and development of negative health outcomes. To investigate practical patterns for stereotactic body radiotherapy to hepatocellular carcinoma in Korea. Prednisolone protects pancreatic B cells against cyclosporine and azathioprine effects.

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The present work specifically addresses the flexibility of the spinal locomotor networks in salamanders. As compared with non-SAD suicide attempters with major depression, SAD patients have an abundant symptomatology, reflected especially by scores on self-reported items. Proper utilization of immunostaining requires that it is employed as a morphology-based technique and not interpreted in isolation. The HEDIS measure, the dispensing of a controller medication among a population with persistent asthma, and the controller to reliever ratio are associated with the risk of subsequent ED visit. We sought to compare feasibility and accuracy of 3DE and 2-dimensional echocardiography (2DE) during exercise echocardiography. The expression of alkaline phosphatase and osteopontin genes increased time-dependently during the osteoblastic differentiation. Chest computed tomography demonstrates solitary or multifocal lesions, sometimes associated with ground-glass opacities or pleural effusion. In contrast, in subjects with small H-reflexes at rest, the reflex peaked at higher levels of contraction for reasons that were elucidated using a realistic computer model. A total of 1089 consecutive DSM-IV bipolar I manic inpatients were subtyped in manic onset (MO), depressive onset (DO) and mixed onset (MXO), and assessed for demographic, illness course, clinical, psychometric, comorbidity and temperament characteristics. SPA-1 is involved in the regulation of T cell activation in response to antigens through the control of Rap1 GTPase signaling.

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