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Acnovate (Adapalene)

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Acnovate is a retinoid. While experts aren't exactly sure how it treats acne, they believe it works by stopping pimples from forming under the skin and lowering the amount of redness and inflammation on the skin.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Benicar, Luvox, Hytrin, Imdur, Motrin, Etformin, Randec, Azithrocin, Aratan, Pertulyn, Zopimin, Benex, Glimaday, Aloric, Coldar,

Also known as: Adapalene


Acnovate is a third-generation topical retinoid primarily used in the treatment of acne. Acnovate is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Acnovate gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Acnovate works under the skin surface to unclog pores and clear up pimples. Acnovate is also known as Adapalene, Adapen, Adaferin. Generic name of Acnovate is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Acnovate exactly as directed. Acnovate is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Acnovate. Acnovate should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Acnovate. Continue using Acnovate until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Acnovate promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Acnovate and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acnovate dosage information

Side effects

The most common side effects associated with Acnovate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of adapalene in the elderly with use in other age groups. Older adults are not likely to develop acne.

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Receiver operator characteristic (ROC) curves generated by performing linear discriminant analysis (LDA), artificial neural networks (ANNs), and classification and regression trees (CART) on OCT-based parameters were compared with the Moorfield regression analysis (MRA), R Bathija (RB), and FS Mickelberg (FSM) functions in the HRT, to classify eyes as either glaucomatous or normal. Histochemical and ultrastructural studies of the heart muscle during electrically induced fibrillation with and without perfusion of the coronary vessels under conditions of moderate hypothermia. In addition, stimulation of purified T cell preparations with rC5a produced little IL-6 activity, suggesting that monocytes are the major source of IL-6 in this system. To assess the incidence and risk factors of early rebleeding after coiling of a ruptured IA and to analyze the outcome of the patients suffering early rehemorrhage. All enrollees were followed after discharge from the clinic or hospital for 4 wk with hematocrit determination and clinical assessments. The effect of heat stress on the growth, physiological state, cell activity and cell morphology of the tropical Sinorhizobium arboris strain HAMBI 2190 was studied. This study presents a comprehensive examination of housing satisfaction in Finland and how it associates with different types of residential area, dwelling and tenure status taking into account socio-demographic and socioeconomic variables. We evaluated the potential of embryonic stem cells for correcting hemophilia A in mice. This minimally invasive procedure requires pneumoperitoneum for adequate visualization and operative manipulation. By means of splice variant-specific in situ hybridization, we could confirm that apoEr2 mRNA is abundantly expressed in brain tissue and, with exception of the newly identified ligand binding domain, all mRNA splice variants exhibited a similar expression pattern.

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