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Acquire (Levofloxacin)

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Acquire is an antibiotic. It is used orally to treat different types of bacterial infections of the throat, lungs, ears, nose, urinary tract, and skin. Acquire is also used with other medications to stop the growth and kill Helicobacter pylori bacteria that cause stomach ulcer(s). It is not effective against infections caused by viruses or fungus.

Other names for this medication:
Alevokem, Armolev, Cinacol, Cravit, Cravox, Elequine, Exolev, Floximax, Iquix, Laiwoxing, Ledric, Lefex, Leflox, Lefoxin, Levobac, Levocin, Levocine, Levoday, Levoflox, Levofloxacinum, Levonidin, Levoprolin, Levox, Levoxa, Levoxin, Locin, Mosardal, Nevotek, Nufalev, Prolecin, Reskuin, Tamiram, Trevox, Volox, Voxin, Xenoxin

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Also known as: Levofloxacin


Acquire (levofloxacin) is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body.

Acquire is used to treat different types of bacterial infections. Levofloxacin is also used to treat people who have been exposed to anthrax or certain types of plague.

Fluoroquinolone antibiotics can cause serious or disabling side effects.

Acquire should be used only for infections that cannot be treated with a safer antibiotic.


To reduce the development of drug-resistant bacteria and maintain the effectiveness of Acquire and other antibacterial drugs, Acquire should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Acquire Oral Solution are indicated for the treatment of adults ( ≥ 18 years of age) with mild, moderate, and severe infections caused by susceptible isolates of the designated microorganisms in the conditions listed in this section.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep in a tightly closed container. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acquire are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use this medicine if you are allergic to levofloxacin or other fluoroquinolones (ciprofloxacin, gemifloxacin, moxifloxacin, ofloxacin, norfloxacin, and others).

Levofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop using levofloxacin. Tendon problems may be more likely in certain people (children and older adults, or people who use steroid medicine or have had an organ transplant).

Tell your doctor if you have ever had:

tendon problems, bone problems, arthritis or other joint problems (especially in children); blood circulation problems, aneurysm, narrowing or hardening of the arteries; heart problems, high blood pressure; a genetic disease such as Marfan syndrome or Ehler's-Danlos syndrome; diabetes; a muscle or nerve disorder, such as myasthenia gravis; liver disease; kidney disease; seizures or epilepsy; a head injury or brain tumor; long QT syndrome (in you or a family member); or low levels of potassium in your blood (hypokalemia).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

You should not breast-feed while using this medicine.

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Evidence for and implications of follicular heterogeneity in pigs. We invited all Piedmont hospital units that had treated at least 5 cases of colon-rectal or breast cancer in 2002 to participate to the survey. Determination of residual DMSO in PAN-Based carbon fiber precursors by HPLC. A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described. These remodelings might be important for the enhancement of freezing tolerance. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2). These chromosomal deletions represent an important resource for genetic studies to dissect the functional content of a genomic region, and several developmental defects have been associated with mice homozygous for distinct piebald deletion alleles. Omega3 fatty acids may inhibit neuronal signal transduction pathways in a manner similar to that of lithium carbonate and valproate, 2 effective treatments for bipolar disorder. The definition, diagnosis and classification of osteonecrosis have evolved since Marx reported the first cases in 2003.

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Relaxing the requirement of orthogonality may allow factor axes to be unduly influenced by chance variation, resulting in spuriously high factor loadings. Ontogenetic diet shifts result in niche partitioning between two consumer species irrespective of competitive abilities. In either case, the timing of regression and molt cannot be explained by absolute prevailing photoperiod or rate of change in photoperiod - birds appear to be using more subtle cues from the pattern of change in photoperiod. Although these studies are heterogeneous and of varied quality, a descriptive synthesis of results suggests that psychoeducational interventions may improve urinary incontinence, bowel bother, sexual function and sexual bother to some extent. The effect of three types of rasps on the occlusal surface of equine cheek teeth: a scanning electron microscopic study.

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The African mosquito Anopheles gambiae is the major vector of human malaria. Did the Sciara SXL protein acquire Drosophila sex-specific functions when the Drosophila N- and C-terminal domains replaced those of Sciara?. Superoxide generation from the reduction of oxygen at the carbon-oil-water triple phase boundary. Assessing participation bias in a population-based study of measles-mumps-rubella vaccine immunity in children and adolescents aged 12-18. The Geriatric Mental State schedule was developed in response to the need to answer the question whether functional psychiatric disorders were being misdiagnosed as organic brain syndrome and, if so, to what extent this influenced treatment and outcome. Consumption of antihistamines and antiasthmatics in Hungary during 1992-1996. Genetic variation was found in the following systems: serum albumin, 6-PGD, haemoglobin, esterase, IDA and GPI.

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Patients initiating therapy on sertraline or paroxetine were less likely than patients initiating therapy on fluoxetine to have four or more prescriptions of their initial antidepressant within the first 6 months. In this paper, we present a case of near hanging with neck soft tissue injury, tracheal and esophageal rupture that is complicated by a displaced intubation and false passage to the trachea. Sector transducers with frequencies between 5 and 10 MHz are useful for dogs and cats. By using manual aspiration, cells were then processed by aspiration alone, by 20-G vitrectomy at 600 cuts per minute (cpm) and 1,500 cpm, or by 25-G vitrectomy at both 600 and 1,500 cpm. The present studies were undertaken to investigate whether or not decreased ambulatory activity, including abnormal feeding behavior in diabetic rats, will be simultaneously normalized by insulin administration. Estimating the change of carbon in the terrestrial biosphere from 18 000 BP to present using a carbon cycle model.

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Although prolonged expression of Sox2 caused cell proliferation and epithelial hyperplasia, Sox2 did not induce pulmonary tumors. Sensitometric characteristics of medical roentgenographic and fluorographic films. The highest airborne levels of culturable bacteria and gram-negative bacteria were identified in the finishing units. An oval shaped piece of cartilage with perichondrium on one side was harvested from the cavum conchae. This accelerated damage was not reversed by subsequent restoration of calcium. The ability to utilize double-stranded RNA (dsRNA) to inhibit specific gene function in this organism has dramatically increased its value for these kinds of studies and has provided more flexibility in experimental design that include procedures. Alpha 2-adrenergic receptor-mediated presynaptic inhibition of GABAergic IPSPs in rat histaminergic neurons. is determined by the molecular weight of individual metabolites.

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It was found that apparently healthy adult deer were shedding low numbers of oocysts in their faeces throughout the year and that there appeared to be a periparturient increase in the numbers of oocysts shed. Aortic tissue samples were evaluated by real-time polymerase chain reaction (RT-PCR) for MMP-9, by immunohistochemistry for elastin. We have previously documented that Akt activates integrins and Akt1 deficiency results in matrix abnormalities in skin and blood vessels in vivo. A novel interaction of CLN3 with nonmuscle myosin-IIB and defects in cell motility of Cln3(-/-) cells. One hundred and one urticaria patients who showed positivity to at least one allergen on a MAST completed a questionnaire regarding their test results. ducreyi 35000HP bound to fibronectin, laminin, and type I and III collagen but not to type IV, V, or VI collagen or elastin. Biological macromolecules, and the complexes that they form, can be described in a variety of ways ranging from quantum mechanical and atomic chemical models, to coarser grained models of secondary structure and domains, to continuum models. Ch 7alpha-OOH and Ch 7beta-OOH were present in each sample, being significantly higher in alcoholic samples than in control samples. Whilst ascorbyl palmitate had a similar action in reducing or eliminating NOPyr production, no synergistic effect between it and alpha-tocopherol was noted in an experiment combining the two antioxidants.

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Bactericidal activity of antimicrobial coated polyurethane sleeves for external fixation pins. Insufficient data are provided by a review of the pros and the cons of dummy use to encourage or discourage this habit. In this study, we show that parabasalids, including hypermastigids, can be classified as belonging to the animal--parabasalids clade and the early-branching eukaryote oxymonads can be classified as belonging to the plant--protists clade. Here we report for the first time that electrophoresis of the sample through the short noncooled capillary inlet can lead to large systematic errors in quantitative CE-based affinity analyses. This research used the empirical mode decomposition (EMD) method to de-trend the suicide data into a set of intrinsic oscillations, called intrinsic mode functions (IMFs). These results demonstrate sex dimorphism with respect to thioredoxin, oxidative stress and inflammation, and suggest the differential regulation of blood pressure, the cardiac thioredoxin system and NAD(P)H oxidase activity by angiotensin II in male and female mice. Several alternative design strategies were considered for protecting against incorrectly guessing the Weibull model parameters when their true values are not known. The amount of 5-hydroxythalidomide formed was high in mice, lower in rabbits, and barely detectable in humans. Radiation therapy (RT) and chemotherapy have increased long-term survival with certain cancers. The identified virulence genes included hemolytic toxin cylZ of Streptococcus agalactiae and sortase associated with colonization of pathogenic streptococci.

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In all fracture planes, decoration of individual thin filaments by crossbridges is variable, but usually one (singlet) or two (doublet) closely spaced crossbridges mark each actin target zone, at intervals of 35-38 nm. Anti-parvovirus B19 IgM antibody were positive in the serum and parvovirus B19 DNA was detected in the bone marrow cells by polymerase chain reaction. AS events have been shown to significantly occur in regions where a protein interaction domain or a short linear motif is present. Vibrational characterization and fluorescence optimization of polycyclic polymers. Response assessment of patients with chronic myeloid leukemia receiving imatinib mesylate (Glivec) therapy: experience from a single center in a developing country. The clinical data of 6 patients with aneurysm in the common trunk of malformed superior mesenteric artery and celiac trunk, who were operated on under general anesthesia from 1998 to 2006, were analyzed. With a low detection limit at 0.005 ng mL(-1), this novel immunosensor worked well over the broad linear range of 0.05-30 ng mL(-1). Aneurysmal forms of cervical artery dissection : associated factors and outcome.

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Biochemical parameters of liver function, fasting glucose levels, body mass index (BMI) as well as blood pressure were monitored at 0, 3, 6, and 12 months of therapy. Use of scoring systems to evaluate prognosis and outcome of critical patients. Altered Intrinsic Functional Brain Architecture in Children at Familial Risk of Major Depression. Bronchiolitis Obliterans Syndrome (BOS) remains a major cause of long term morbidity and mortality in lung transplantation, and occurs despite significant immunosuppression. The adopted laser was semi-conducted with a wavelength of 810 nm.

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Induction of the RpoS regulon helps to diminish that sensitivity. Three months after the surgery, control intravenous urography revealed normal findings. Among the 28 metalloproteinases described so far, 23 can be found in the human organism, but only few are expressed in the human brain. Stability and reusability of the catalyst was also investigated. Data were analyzed using conditional logistic regression, adjusted for vaccination target groups, cardiovascular risk factors, treatment medications and attendances at a general practice. Habitat evaluation of wild Amur tiger (Panthera tigris altaica) and conservation priority setting in north-eastern China. GEITP promises to address the need for a rapid and robust method to deliver DNA from crude samples to aid the forensic community in human identification. A new approach to hypoplastic left heart syndrome with an intact atrial septum. Rising of cesarean section rate without any measure to regulate it is the problem in the developing countries. However, conclusions about whether there is a distinct prodrome to BD are restricted by the limitations of current evidence.

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Discussion on the interactions with a boy who experienced death of his friend in a hospital. These findings demonstrate that IL-10 serves a previously unrecognized protective role in muscle progenitors by overcoming TNFalpha-induced resistance to IGF-I. This phenotypic feature is not normally associated with CPHD resulting from PROP1 mutation. Sports-related concussion is a frequently-occurring, serious neurological event that can produce a spectrum of potentially debilitating primary and secondary problems. Based on a YF deletion mutant that requires NS1 in trans, a genetic screen for suppressor mutants was used to select virus variants able to utilize DEN NS1. To differentiate, over a 5-year period, non-compliant (NC) from compliant (C) consumers of psychotropic drugs according to their demographic characteristics and views on: their faith in the prescriber, the effects of consumption, opinion of family and friends and information received.

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Linkage isomers of bis(bipyridine)(1,2-dihydroxy-9,10-anthraquinonato)ruthenium(II), 1,2- and 1,9-coordinated complexes, and several of their oxidation products have been prepared chemically and/or electrochemically. Aerobic exercise, such as running, enhances adult hippocampal neurogenesis (AHN) in rodents. To assess whether Cd modifies expression of two major clock genes, period (Per) 1 and Per 2, in the hypothalamic-pituitary unit and to what extent the changes could be prevented by melatonin, rats were exposed to CdCl(2) (5ppm in drinking water) with or without melatonin (3 microg/mL drinking water) for 1 month and were killed at two time intervals, i.e. A new acylated flavone glycoside from the fruits of Stocksia brauhica. To describe trends and characteristics of foreign-born persons with TB and the implications for TB program planning and policy development. Impact of the biofilm mode of growth on the inner membrane phospholipid composition and lipid domains in Pseudomonas aeruginosa. Platelet activation independent of pulmonary inflammation contributes to diesel exhaust particulate-induced promotion of arterial thrombosis.

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Can we reduce the cardiovascular risk in peritoneal dialysis patients?. One way to perform gene editing in the mouse using the CRISPR/CAS system, guide RNA (gRNA) and CAS9 mRNA transcribed in vitro are microinjected into fertilized eggs that are then allowed to develop to term. The DUOX2 mRNA and protein levels in the gastric cancer and CRC were increased compared to the adjacent nonmalignant tissues. However, during metaphase, this complex is replaced by an astrin-CLASP1 complex, which promotes kMT stability, chromosome alignment, and silencing of the SAC. Blood and plasma viscosity, erythrocyte filtrability and blood gas analysis were determined in 25 subjects with arteriosclerosis obliterans of the lower limbs before and after a muscle exercise test. The purpose of this study was to design a valid questionnaire to the Iranian culture for dementia diagnosis and more specifically in its early stage. Commentary: why the educational effect is so strong in differentials of mortality in Korea?. For a clearance of less than 30 ml/min/1.73 m2, the cut-off value was 177 mumol/liter for men and 146 mumol/liter for women. This protease inhibitory effect could also be found in kidney homogenates in vitro on casein plates and lasted until 48 h post injection. FUSE and its binding protein may contribute to cell line- and differentiation-specific modes of c-myc regulation.

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Whether improved methods of dysphonia screening leads to better outcomes and reduced societal impact needs investigation. Samples taken from 6-month-old deer calves, both in-house and on pasture, had low numbers of Cryptosporidium oocysts, indicating that the calves were also asymptomatically shedding oocysts. These variables were used together with D1D2MFS indices in multiple regression models. In serum of the family, 43-truncated CD13 was extremely concentrated, suggesting that proteolytic cleavage of CD13 amino acids 43 and 44 (43-truncation) is abnormally promoted. Various forms of misunderstanding and culturally ignorant practices were found in the treatment of eight Japanese clients by these Western therapists. Dabigatran is an oral direct thrombin inhibitor for which routine laboratory monitoring is currently not recommended. The roxithromycin side effects with alcohol relation between stress, stress coping behavior and job satisfaction was investigated for psychiatric nurses who work in the northern part of Kyushu and the Chugoku district of Japan.

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Role of Akt inhibition on Notch1 expression in hepatocellular carcinoma: potential role for dual targeted therapy. Vimentin IF were observed to be attached to these organelles laterally or terminally. The results obtained suggest that an increase in the content of cobalt results in an increase in amorphicity level and in an increase in the number of hydroxyl groups. In addition to serving a large number of citizens, oral health care in Texas faces challenges of geographic diversity and a long border with Mexico. Constricted life space is associated with greater risk of death in older community-based persons. These findings strongly support the concept that thyroid hormone of maternal origin exerts specific receptor-mediated effects on fetal brain development. Using cDNA library screening, we have documented the freeze-induced up-regulation of a number of genes in wood frogs including both identifiable genes (fibrinogen, ATP/ADP translocase, and mitochondrial inorganic phosphate carrier) and novel proteins (FR10, FR47, and Li16). Fellowship training can play an integral role in does flagyl treat stomach infection the preparation of family physicians for rural practice. Multiple reflections between two surfaces of a window introduce a fixed pattern error in optical measurements. A polylactide film placed inside the pericardium or between the heart and sternum was able to limit adhesion formation and maintain the anatomical planes, which would facilitate reentry.

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Such inhibitors represent a potential therapeutic approach, offering a mechanism to slow or even redress established renal fibrosis. Education about cancer risk may be more effective if delivered in a health-promoting rather than disease-detection framework. It has been shown, compared with placebo, to be an effective and well-tolerated treatment for major depressive disorders (MDD) in both primary and specialist care settings. Black widow bites do not produce marked skin changes but primarily produce muscle cramping, pain, and other neuromuscular-related symptoms. Immunochemistry revealed a lack of proliferating cell nuclear antigen-positive hepatocytes and F4/80-positive macrophages in and around areas of centrilobular necrosis in APAP-treated Vnn1 knockouts. To study the ability to control magnetic nanoparticles within micrometer-sized channels, Fe2O3, MnFe2O4, and Au nanoparticle samples were compared.

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In contrast, hypoxia did not induce bFGF expression in pulp cells. Cutaneous manifestations of hydroxyurea therapy in childhood: case report and review. In families with two or three children the highest fertility rates were seen in families who had same-sexed children. The effect of the exogenous protein kinase C (PKC) activator phorbol-12,13-diacetate (PDAc) on the early (0-10 min) time course of long-term potentiation (LTP) has been studied in the CA1 region of the guinea pig hippocampal slice. While glycogen provides the only source of energy for the white fibres, glycogen as well as fat serves as fuel for the red fibres. Study 1 described the development of a scale that measures negative interpretations of positive social events, the interpretation of positive events scale (IPES). It is possible that downstream signaling pathways diverge in distinct classes of vertebrates.

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The high and specific reactivity of Hsp90 cysteine groups toward cytochrome c may indicate a role of this chaperone in modulation of the redox status of the cytosol in resting and apoptotic cells. self-organising maps (SOMs), trained with 11 of the 27 variables, were used to extract knowledge about the variable values for each group of patients. The harmful effects could appear not only in mother, but also in fetus. Biobehavioral variables and mortality or cardiac arrest in the Cardiac Arrhythmia Pilot Study (CAPS). We found that endothelial cells in PPH plexiform lesions demonstrated microsatellite instability within the human MutS Homolog 2 gene (10 of 20 lesions) and displayed microsatellite site mutations and reduced protein expression of transforming growth factor-beta receptor type II (6 of 19 lesions) and Bax (4 of 19 lesions). Antibody H7-7 selected against cells expressing Vlp7 in vitro and in vivo, an indication that Vlp7 was a conformation-sensitive antigen for the antibody. We therefore investigated the molecular mechanism by which extracellular hIAPP mediates pancreatic beta-cell apoptosis. Molecular cloning and expression of the nucleoside deoxyribosyltransferase-II gene from Lactobacillus helveticus.

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This adhesion molecule might serve as a treatment target for the fully humanized anti-L1CAM antibody currently under development for clinical use. Electrorotation is a noninvasive technique that is capable of detecting changes in the morphology and physicochemical properties of microorganisms. The effects of a selective protein kinase C inhibitor, H-7 on the proliferation of HuH-7 and 3T3 fibroblasts stimulated by hepatoma-derived growth factor were examined by DNA synthesis and cell growth assay. Type 1 and 2 patterns required no surgical treatment and were rated good to excellent according to the Hospital for Special Surgery Disability Score Sheet. Comparative evaluation of the myocardial resistance of animals with hereditary hypertension and normal arterial pressure to the damaging action of stress. Forty years of biochemical and physiological research illustrate the great difficulty in translating research at the basic level into improvements in crop yield. A Longitudinal Study of Skeletal Histomorphometry at 6 and 24 Months Across Four Bone Envelopes in Postmenopausal Women With Osteoporosis Receiving Teriparatide or Zoledronic Acid in the SHOTZ Trial. This short review describes the distribution of functional Na,K-ATPase activity and Ca-ATPase activity in the lens. Fetus exists in a complex, dynamic, and yet intriguing symbiosis with its mother as far as fuel metabolism is concerned. Two phase II studies published to date demonstrate both efficacy and safety.

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Serious adverse liver reactions associated with herbal weight-loss supplements. Phosphorus deficiency is one of the major nutrient stresses affecting plant growth. Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults, with a median survival of 13 months despite surgery and chemoradiation. The inhibitors ventolin inhaler dose medscape of MRP(2) and BCRP can promote transportation of scutellarin. In reconstructing the scalp defect, this method was found to adhere to principles of scalp reconstruction. Invisible scar endoscopic dorsal approach thyroidectomy: a clinical feasibility study. Enzymology studies have enabled different models for their action mechanism to be proposed.

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