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Actazid (Acetazolamide)

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Actazid is a carbonic anhydrase inhibitor that affects your body's fluid balance. It helps remove water and electrolytes in your urine, lowers the amount of fluid in your eyes. It calms your nervous system, and allows your body to use oxygen better at high altitudes.

Other names for this medication:
Abzole, Aceact, Acetamide, Acetamin, Acetariv, Acetazolamide, Actamid, Actamide, Actazid, Antilep, Axytex, Carbadac, Iopar, Mazetol, Mezapin, Synomax, Tegrital, Zolamide

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Also known as: Acetazolamide


Actazid reduces the activity of a protein in your body called carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body.

Actazid is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.

Actazid is also used as a diuretic ("water pill") in people with congestive heart failure, to reduce the build-up of fluid in the body. This build-up is called edema.

Actazid is also used to treat certain types of seizures, and to treat or prevent altitude sickness.


Actazid is available in tablets. The dosage depends on the disease and its prescribed treatmen. Glaucoma treatment: 250 mg to 1 gram per 24 hours in 2 or more smaller doses. In secondary glaucoma and before surgery in acute congestive (closed-angle) glaucoma, the usual dosage is 250 mg every 4 hours or, in some cases, 250 mg twice a day. Epilepsy treatment: The daily dosage is 8 to 30 mg per 2.2 pounds of body weight in 2 or more doses. Typical dosage may range from 375 to 1,000 mg per day. Congestive Heart Failure treatment: The usual dosage is 250 mg to 375 mg per day or 5 mg per 2.2 pounds of body weight, taken in the morning. Actazid can be used by children. If you want to achieve most effective results do not stop taking Actazid suddenly.


If you overdose Actazid and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actazid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Actazid if you are allergic to Actazid components. Be careful with Actazid if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Actazid if your sodium or potassium levels are low. Do not take Actazid if you have kidney or liver disease, including cirrhosis. Be careful with Actazid if you suffer from or have a history of emphysema or other breathing disorders. Be careful with Actazid if you take high doses of aspirin. Be careful with Actazid if you are taking Amitriptyline, Cyclosporine, Lithium, Methenamine, oral diabetes drugs such as Glyburide, Quinidine. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Do not stop taking Actazid suddenly.

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The amount of five-coordinated high-spin iron and a positive reduction potential were found to promote the oxygenase activity of the proteins. Artifactual support derived from base pairs was generally reinforced by the incorporation of gap characters for progressive pairwise alignment, local pairwise alignment, and implied alignments. Lidocaine treatment improved early electrophysiological recovery and reduced the size of the cortical infarct at 24 h, but had no significant effect on cerebral blood flow in either the penumbra or core during ischemia. The National Cholesterol Education Program recently issued guidelines for treatment of hyperlipidemia in adults including diabetic patients. A study was made of the genotype distribution of the different polymorphisms in our group of patients with neovascular AMD and those with the atrophic type, and a comparison was made of the results for each one of the genes studied. Although multiple methods of operative and nonoperative drainage of pericardial effusions have been described, surgical pericardial window remains the standard approach to long-term drainage.

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We provide an overview of the four specific projects funded by the CDC as well as a short discussion of some of the many challenges encountered during their implementation. Regulation of PDGFR-alpha in rat pulmonary myofibroblasts by staurosporine. Differences in the production of methemoglobin during high-dose treatment with isosorbide dinitrate or isosorbide 5-mononitrate. To investigate the effect of dehydroepiandrosterone (DHEA) on mouse decidual endometrial stromal cells (ESCs) and to explore mechanisms regulating endometrial receptivity. The Alterations of Erythrocyte Phospholipids in Type 2 Diabetes Observed after Oral High-Fat Meal Loading: The FTIR Spectroscopic and Mass Spectrometric Studies. As a result, it has been determined that development of a modern trauma system and trauma centers have significant roles in decreasing preventable death ratios. These contacts were classified as 1) synaptic input, with asymmetric synapses seen between a nonimmunoreactive axon terminal and a LHRH-immunoreactive cell body or a nonimmunoreactive axon terminal and a LHRH-immunoreactive dendritic process. A greater endothelial dysfunction was observed in patients with ischemic heart failure compared to those with dilated cardiomyopathy, implying that the underlying atherosclerosis may participate in this process. Low-dose IFN-alpha therapy is associated with significant prefrontal hypometabolism.

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The use of Gn-RH-a in the context of hirsutism is not duration-limited in that the induced hypoestrogenism and its consequent complications are likely to be effectively managed by the concurrent provision of estrogen replacement therapy. Variations in telomere length have been reported in severe aplastic anemia but their clinical significance is unknown. Biconcave contact lenses: a critical analysis of their optical properties. We conclude with an overview of some current major issues and future prospects, ranging from the search for disease markers to challenging developments such as stem-cell and gene therapy. Results of intravesical CDDP or CDDP combined with external beam radiation are compared in a group of 13 patients with low-stage bladder cancer. Ethics approval has been obtained from the ethics committees of the participating hospitals and universities. Consequently, autonomic physiology may serve as a window into non-motor PD progression and allow the development of mechanistically based treatment strategies for several non-motor features of PD. Atrial fibrillation (AF) ablation relies increasingly on three-dimensional (3D) visualisation tools to help guide an operator in performing a procedure safely and successfully.

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Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data. In this study, a kind of green waste (perennial ryegrass) was used as carbon source to adjust carbon to nitrogen ratio (C/N) in WAS to enhance SCFAs production. The inhibitor had no effect on thrombin activity as measured with the synthetic, chromogenic substrate BZ-Phe-Val-Arg-pNA. Because of the inordinate fragility of the blood vessels in patients with this syndrome, conservative treatment is always indicated. A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host/parasite model. The Trypsin-like-immunoreactivity test is recommended for establishing the diagnosis. Provirus was not detected in another 6, all of whom were neurologically normal.

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The primary outcome was in-hospital mortality and mortality at 30, 60, 90, 180, and 365 days. Two general types of cristopathies are defined predicated on the abnormal mechanism involved in production of the defect or condition. Detecting brain activation in FMRI data without prior knowledge of mental event timing. We retrospectively analyzed data from all patients undergoing orthotopic liver transplantation in our unit from December 1999 to November 2005, on the admission day MELD and CTP scores were calculated for each patient according to the original formula. Inverse scattering from phaseless measurements of the total field on a closed curve. Perfusion MRI had moderate sensitivity and specificity in the differential diagnosis between lesions with high or low biological activity. In an attempt to determine whether the finding of human ocular lesions due to B. Among children with higher RBP4, the association with obesity increased significantly (from 3.1 to 8.5) in the presence of insulin resistance, when compared to higher RBP4 and non-insulin resistance.

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As a theoretical model, sensemaking may offer an alternative lens through which to view the phenomenon of nurse/physician communication and advance our understanding of how nurse/physician communication can promote patient safety. Finally, because the 5-HT1B receptor inhibits glutamate release, our results suggest that visual and somatosensory projections must release glutamate for proper segregation. Clinical performance of a levonorgestrel-releasing intrauterine system and oral contraceptives in young nulliparous women: a comparative study. The increase in Isc induced by GR-73632 was significantly attenuated by tetrodotoxin (TTX, 1 microM), indicating that TAK-637 inhibits neuronal NK(1) receptors. Because bile secretion by hepatocytes is apparently mediated by the microfilamentous system of actin, the proposed hormonally induced dysfunction of this system could be translated to cholestasis. In addition, ZNF668 knockdown decreased RPA phosphorylation and its recruitment to DNA damage foci in response to UV. In addition, mean PEF variability decreased significantly in the treatment group.

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Debriefing in the intensive care unit: a personal experience of critical incident stress. Our goal was to determine the effects of enriched foods and exercise on blood vitamins, Hcy, MMA, and neuropsychological functioning in the frail. Gonadotropin-releasing hormone inhibition of LH stimulated progesterone secretion by porcine granulosa cells in vitro. Vertical transmission of human immunodeficiency virus (HIV) represents an important worldwide health problem and rapid decline in viral load is essential for HIV pregnant women to prevent mother to child transmission. The results reported in this paper show that the performance of such a pulsed jet is far superior to that of a continuous jet operating at the same parameters. Genistein-sensitive tyrosine kinases may therefore abrogate a latent sensitivity of neural crest cells to contact-mediated inhibition of movement. A worldwide spread is conceivable and norovirus diagnostic assays need to be evaluated to investigate if they adequately detect this emerging genotype. This work theoretically presents a new heating strategy which is capable of both increasing the treatment conformability and shortening the treatment time, when using a 2D ultrasound phased array transducer. Antiphospholipid antibodies and the risk of recurrence after a first episode of venous thromboembolism: a systematic review. An escape from this physiological process may be associated with certain myeloproliferative neoplasms leading to abnormal megakaryocytic proliferation.

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