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Actidrox (Cefadroxil)

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Actidrox is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic. It was patented in 1967 and approved for medical use in 1978.

Other names for this medication:
Actidrox, Cedrox, Cefadil, Cefadroxil, Cefastar, Eliminate, Paxyl

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Also known as: Cefadroxil


Actidrox (formerly trademarked as Duricef) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic.

Actidrox is a first-generation cephalosporin antibacterial drug that is the para-hydroxy derivative of cefalexin, and is used similarly in the treatment of mild to moderate susceptible infections such as the bacterium Streptococcus pyogenes, causing the disease popularly called strep throat or streptococcal tonsillitis, urinary tract infection, reproductive tract infection, and skin infections.


Actidrox is acid-stable and may be administered orally without regard to meals. Administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with oral cephalosporin therapy.

Urinary Tract Infections: For uncomplicated lower urinary tract infections (i.e., cystitis) the usual dosage is 1 or 2 g per day in a single (q.d.) or divided doses (b.i.d.).

For all other urinary tract infections the usual dosage is 2 g per day in divided doses (b.i.d.).

Skin and Skin Structure Infections: For skin and skin structure infections the usual dosage is 1 g per day in single (q.d.) or divided doses (b.i.d.).

Pharyngitis and Tonsillitis: Treatment of group A beta-hemolytic streptococcal pharyngitis and tonsillitis—1 g per day in single (q.d.) or divided doses (b.i.d.) for 10 days.


If the patient misses a dose, the dose should be taken as soon as it is remembered. Doses thereafter should then be evenly spaced with approximately 4-6 hours between doses, depending on the prescription dosing. Patients should not make up a missed dose by doubling up on their medication. Taking double doses will not speed recovery time, either. Taking doses close together or self administering a double dose is likely to cause an overdose which may lead to other health complications. An overdose may cause nausea, vomiting, diarrhea, dehydration, and abdominal cramps and requires immediate medical assessment.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days.

Detailed Actidrox dosage information

Side effects

The most common side effects associated with Actidrox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefadroxil in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefadroxil.

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Gastric body cholinergic contractile signal transduction in M2 and M3 receptor knockout mice. In this study, we show that a functional ubiquitin pathway is not required for the proteasomal degradation of the endogenous Daxx protein by tegument-delivered pp71 in HCMV-infected cells, demonstrating that the pp71-mediated degradation of Daxx occurs through a proteasome-dependent, ubiquitin-independent pathway. It is well known that high sodium intake is closely associated with the risk of cardiovascular disease, but the effect of low sodium intake on insulin resistance is not clear. The presence of deoxycytidine (dCyd) caused a reduction of AP-induced SCEs to about control level while addition of deoxythymidine (dThd) enhanced SCE induction. Integrated electromyography was used to compare activation between the 14 massage techniques used.

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Three patients with branch vein occlusion (BVO) were studied, with duration of symptoms less than 25 days, and mean follow-up period of 18.8 months. Our results showed that repeated predatory stresses may result in a pattern of intensive behavioral and endocrinal responses, and lead to the neuronal cell loss in hippocampus. It has been shown previously that osteoblast differentiation and maintenance of bone mass are impaired in endothelial nitric oxide synthase gene knockout mice. Nerve growth factor-induced growth of sympathetic axons into the optic tract of mature mice is enhanced by an absence of p75NTR expression. It is related to the concept of kinetic trapping, which often occurs during self-assembly. There were no other significant differences in either population in times to provision of clinical care or in clinical outcome. To describe the traditional diet of Crete and evaluate the nutrient composition of 3 types of diet common in Crete by means of chemical analyses of composite food samples. One reference tertiary amine and three families of structurally related trialkylamines and dendrimers have been synthesized, characterized, and studied by molecular dynamics simulations. The skin texture and color match is ideal for pinna reconstruction. Furthermore, the fluorescence polarization of epsilon-ADP bound to F-actin which is oriented in the field of flow shows that the emission dipole is nearly perpendicular to the long axis of F-actin.

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We compared the ultrasonographic parameters for endometrial receptivity between 2 consecutive in vitro fertilization (IVF) cycles in the same patients. This activity of GAP, which can increase with cell density in contact-inhibited cells, suggests that it functions as a negative, upstream regulator of ras. Etiologic characteristics of food-borne Vibrio parahaemolyticus strains isolated in Guangdong, 2014. Pulmonary function tests were performed before and after PE lesson. Mice bearing human xenografts were treated with weekly intravenous injections of volasertib. The use of daily IGRT is beneficial for reducing the incidence of late toxicities. Stool specimens and clinical data were collected from 346 inpatients with acute diarrhea from children less than 5 years old. Our data also suggested that inhibition of pAkt and activation of p53 pathway are the main molecular events involved in inhibitory effects of TSA. The other mutations introduced led to greatly reduced levels of enzyme activity which correlated with a reduced or altered ability of the mutant enzymes to bind ATP as determined by ATP-agarose affinity chromatography.

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Procedure for outpatient argon laser iridectomies for angle-closure glaucoma. The patients with OCD demonstrated a significant reduction of GM volume in the bilateral medial prefrontal cortex, right premotor area, right orbitofrontal cortex (OFC), right dorsolateral prefrontal cortex, and bilateral temporal and occipital regions. Using Madin-Darby canine kidney (MDCK) cells as an in vitro model of polarized epithelia, our laboratory has previously shown that the COOH-terminal cytoplasmic 22 amino acids of the GAT-2 isoform of the gamma-amino butyric acid (GABA) transporter are necessary for its basolateral distribution. The present study describes the interaction of two nonsteroidal anti-inflammatory drugs (ibuprofen and piroxicam) with PLA(2) from Naja mossambica mossambica and seeks to deepen the knowledge about the influence of the biophysical properties of biomembranes, and the inhibitory effect of the drugs on the enzymatic activity. Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs: importance of gastric hypermotility. Heteroanionic Materials Based on Copper Clusters, Bisphosphonates, and Polyoxometalates: Magnetic Properties and Comparative Electrocatalytic NO(x) Reduction Studies. Attention to long-term side-effects, including cardiovascular toxicity, is therefore of growing importance.

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Abdominal pain is the most frequent symptom of chronic pancreatitis and may, on occasions, lead to great treatment problems. Implications for the clinical researcher and practitioner are briefly discussed. Schwann cell-derived factors modulate synaptic activities at developing neuromuscular synapses. PARP knockout mice and the derived mouse embryonic fibroblasts (MEFs) were acutely sensitive to monofunctional alkylating agents and gamma-irradiation demonstrating that PARP is involved in recovery from DNA damage that triggers the base excision repair (BER) process. LeVeen shunt (LS): long-term therapy for idiopathic ascites of chronic renal failure. The positive likelihood ratio was smaller than 1, thus indicating lack of diagnostic power of the exfoliation of the deciduous second molars with regard to CS3. Effect of mexidol on hemopoietic system in conditions of an emotional stress after exposure to ionizing radiation. To appraise the composition effect of the composite compared with pure materials, the quantitative formula of the composition effect has been provided for the first time in this paper. Variability in aggressiveness of rice blast (Magnaporthe oryzae) isolates originating from rice leaves and necks: a case of pathogen specialization?.

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Isolation of Ross River virus from mosquitoes and from horses with signs of musculo-skeletal disease. The inclusion of such visualizations within other CG or VR environments may ultimately provide the potential for alternative exploratory directions, processes, and results within forensic pathology investigations. Elevation in any plane anterior to the scapula required external humeral rotation, and maximal elevation was associated with approximately 35 degrees of external humeral rotation. This phenomenon of Reverse Crossed Cerebellar Diaschisis is rare and has been describe only in Single Photon Emission Computed Tomography (SPECT). The 100 responses from four Australian states were subject to analysis of suture type and size used for various procedures and correlated with practice type, location and state. Epitope-specific acticin antibodies to the M1 and M2 subunits of mammalian ribonucleotide reductase were prepared using peptides predicted to have a high antigenic index. Asparagine synthetase was overexpressed and knocked down in HCC cell lines to assess the influence of the enzyme on cell proliferation, migration and tumourigenicity.

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Intratracheal administration of interleukin-10 (IL-10) has been reported to inhibit allergic inflammation but augment airway hyperresponsiveness (AHR). We detected a substitution Glu480Lys that would be located in its second ectoplasmic loop. Despite primary care reforms and incentives, and promotion of cancer-screening programs among individuals, participation is suboptimal. Based on the favorable clinical results of this study, it can be summarized that the flexible RPDs is a glucotrol medication class viable alternative to cast RPDs in Kennedy Applegate class II partially edentulous situation in the short term. Dynamic CTP has a potential to detect abnormal perfused myocardium and severe infarction assessed by SPECT/CMR using comparable cut-off MBF. The electrically evoked and voluntary contractile properties of the first dorsal interosseous muscle were measured on both hands in 10 healthy adults. Implications of the results for translational selection are discussed. Effects of supranormal liver glycogen content on hyperglucagonemia-induced liver glycogen breakdown.

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Carotid artery stenting for carotid bifurcation stenosis usually uses the transfemoral approach. A comparative study on the impact of phthalate esters on soil microbial activity. Our data indicate that normal ECM formation requires Chts, which potentially hydrolyze chitin-polymers. Hepatitis B antigen in children with chronic hepatitis and liver cirrhosis. Study of GeSn based heterostructures: towards optimized group IV MQW LEDs. Serum zinc levels were not significantly higher in patients treated with dapsone for approximately 18 months. Use of higher contrast enhancement can compensate for the degradation of image quality resulting from use of a low radiation dose for CT.

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