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Addaprin (Ibuprofen)

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Addaprin is a pain-relieving medicine. It is used to treat many conditions such as headache, fever, period pain, toothache, colds, and mild arthritis. It is also a common ingredient in many cold and flu remedies.

Other names for this medication:
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Also known as: Ibuprofen


Addaprin is produced with efficacious pharmacy formula making Addaprin wonderful weapon against pain, fever, inflammation. Target of Addaprin is to prevent pain. Addaprin acts as popular medicine which can not only provide protection from painful sensation but also it protects from fever. Addaprin acts blocking hormones of pain. Addaprin is also known as Ibuprofen, Brufen, Ibugesic, Advil, Anadin Ibuprofen, Arthrofen, Cuprofen, Fenbid, Galprofen, Hedex Ibuprofen, Ibufem, Librofem, Mandafen, Manorfen, Migrafen, Nurofen, Obifen, Relcofen. Addaprin is NSAIDs (nonsteroidal anti-inflammatory drugs). Addaprin can't be used by patients under 2 years.


This section provides information on the proper use of a number of products that contain ibuprofen. It may not be specific to Children's Addaprin. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients .

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine .

To lessen stomach upset, you may take this medicine with food or milk .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets and suspension): For fever: Children over 2 years of age—Use and dose must be determined by your doctor. Children 6 months of age up to 2 years—Dose is based on body weight and body temperature, and must be determined by your doctor. For fever lower than 102.5 °F (39.2 °C), the dose usually is 5 milligrams (mg) per kilogram (kg) (about 2.2 mg per pound) of body weight. For higher fever, the dose usually is 10 mg per kg (about 4.5 mg per pound) of body weight. The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For menstrual cramps: Adults—400 milligrams (mg) every four hours, as needed. Children—Use and dose must be determined by your doctor . For mild to moderate pain: Adults and teenagers—400 milligrams (mg) every four to six hours, as needed. Children over 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose usually is 10 milligrams (mg) per kilogram (kg) of body weight every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For osteoarthritis and rheumatoid arthritis: Adults and teenagers—1200 milligrams (mg) up to 3200 mg per day divided into three or four equal doses. Children—Dose is based on body weight and must be determined by your doctor. The dose usually is 30 milligrams (mg) to 40 mg per kilogram (kg) of body weight per day, divided into three or four doses. Infants younger than 6 months of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Addaprin Childrens dosage information

Side effects

The most common side effects associated with Addaprin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Ibuprofen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use Addaprin PM just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Addaprin PM, especially in older adults.

You should not use this medicine if you are allergic to diphenhydramine or ibuprofen, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

heart disease, high blood pressure; a heart attack, stroke, or blood clot; stomach ulcers or bleeding; a breathing problem, such as asthma, emphysema, or bronchitis; liver or kidney disease; glaucoma; enlarged prostate or problems with urination; or if you take aspirin to prevent heart attack or stroke.

Ask a doctor before using this medicine if you are pregnant or plan to become pregnant. Taking ibuprofen during the last 20 weeks of pregnancy may result in serious kidney problems in the unborn baby.

Ask a doctor before using this medicine if you are breastfeeding.

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In contrast, all three cell lines were found to express desmoglein, desmoplakin and c-Met. Physician-patient interactions regarding diet, exercise, and smoking. This MSA seems to be an effective and safe treatment alternative to microsurgery, above all in patients with regrowing/recurrent cystic CPs. Records were examined for demographics, diagnoses, procedures, and complications. We have previously shown that continuous intra-arterial combination chemotherapy (IACC) might be more effective for advanced hepatocellular carcinoma (aHCC) in patients with HCV-related liver cirrhosis (C-LC) or alcoholic liver cirrhosis (A-LC) than in patients with HBV-related LC (B-LC). To conduct targeted outreach within an intervention trial to recruit HIV-infected drug users and assess HIV disease and nutritional status. We conclude that mesangial cells might be a target for the treatment of inflammatory glomerulopathies with 9-cRA. Dexamethasone modulates ErbB tyrosine kinase expression and signaling through multiple and redundant mechanisms in cultured rat hepatocytes. Inhaled nitric oxide (NO) was used to improve oxygenation, thereby facilitating cerebral aneurysm clipping.

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Postmenopause hormone treatment in women with NIDDM or impaired glucose tolerance: the MEDIA randomized clinical trial. A hospitalwide preintervention-postintervention study was conducted over 2 years (July 1, 2004, through June 30, 2006). Redescription and new locality record of Choleoeimeria turcicus from the gallbladder of Hemidactylus turcicus in Egypt, with notes on its endogenous development. Magnetic resonance imaging (MRI) tomography or X-ray computed tomography visualized lacunar lesion(s) in the upper brainstem tegmentum in all of three cases. The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging.

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These results suggest that heme adduct formation may result from mifepristone metabolism by CYP3A monooxygenases which undergo self-catalysed irreversible inactivation with this drug as substrate. We conducted a retrospective multicenter study, involving eight centers, of PI from January 2001 to December 2010. This paper reviews the literature on potential causes of chronic hepatitis in dogs (infectious, autoimmune, metabolic, toxic, and breed-associated) together with the literature on the progression of the disease and on treatments. The association of sexual and physical abuse with somatization: characteristics of patients presenting with irritable bowel syndrome and non-epileptic attack disorder. These results indicated that the chronic lymphatic inflammation occurring in pelvis or behind peritoneum due to perennial stimulation of adult filariae, caused the high concentration of inflammatory medium tissues, the expansion of micro-vessels and the increase of lymph-vessel pressure. Risk for malignant tumors after oral contraceptive use: is it related to organ size while taking the pill?. Very few shocks were required, and documented retropulsion was minor. The purpose of this study was to clarify the role of fibroblasts in tumor progression in non-small cell lung cancer (NSCLC). The present results confirm this hypothesis, since intracerebroventricular (i.c.v., 50 ng) and local (0.5 ng) injections of OXT and Z-Pro-D-Leu into the dorsal hippocampus and the mesolimbic nucleus accumbens attenuate morphine tolerance/dependence, similarly to systemic injections of these peptides in higher amounts (5-50 micrograms). Decreased placental protein synthesis and increased protein degradation were observed in both the tumour-bearing and the ascitic fluid-injected groups that were fed a normoprotein diet.

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Incidence of disorders of the Q wave, the S-T segment and the T wave in the population of Cracow. METHODS: A long-term prospective study of all-cause mortality and cardiovascular mortality has been conducted in Ohasama, Japan since 1987. Verapamil and amlodipine produced a potent antiischemic effect and reduced the area of myocardial infarction in rats. Acromegalic patients treated three times daily with subcutaneous injections of the somatostatin analogue octreotide frequently develop gallstones, due to suppressed cholecystokinin release and impaired gall-bladder emptying. After an esophagectomy, most patients struggle with nutrition-related symptoms, are confronted with nutrition-related adjustments and a reduced body weight. Fructose concentration was studied in the ejaculates of 20 intact and 19 vasectomised rams over a two year period. The radio frequency (RF)-induced heating is a major concern when patients with medical devices are placed inside a magnetic resonance imaging (MRI) system.

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Maximum principal stresses in the molar with amalgam restoration occurred at the pulpal floor and lingual wall junction and resulted from large occlusal loads. Pharmacokinetic drug interactions may result in a decrease or increase in the oral bioavailability of some drugs. Expression of bovine (Bos indicus) interleukin-18 in Escherichia coli and its biological activity. Significance of vascular changes in the colposcopic diagnosis of precancerous and early stages of cervical cancer. MDMA appears to produce a major release of dopamine from its nerve endings in all species investigated. They draw on a synthesis of the literature and their research experience and propose a three-stage checklist summarizing strategies that worked for them and addressed some of the problems described in the literature.

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Adult cardiac myocytes are terminally differentiated cells that are no longer able to divide. As the RBE depends on the linear energy transfer (LET), we present a fast method for three-dimensional calculations of the dose-averaged LET. A shift towards a T cell cytokine deficiency along with an anti-inflammatory/regulatory microenvironment may enable the synthesis of anti-FVIII inhibitors in haemophilia A patients. Although quorum sensing (QS), a bacterial signaling mechanism, coordinates differentiation of biofilms in vitro, wild-type and QS-deficient P. Injection is into the abdominal cavity, posterior to the pelvic girdle. The procedure is both an accurate diagnostic tool and an effective treatment of many thyroid nodules. The concentrations of both these inhibitors were highest the day after parturition, and were about one-tenth as much on day 7. The key suggested problem causing the osteonecrosis is vessel thrombosis within the smaller vessels of the bone flap due to the prothrombotic effects of the factors released during drilling of the bone flap.

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To examine the Canadian health system, in particular as it relates to health care, and to assess the functions of the provincial and federal governments in relation to health care, spending, funding, and reform. We report a case of abdominal actinomycosis in a young woman wearing an intrauterine contraceptive device. Non-invasive in vivo quantification of the medial tibial cartilage thickness progression in an osteoarthritis rabbit model with quantitative 3D high resolution micro-MRI. The aim of the research reported here was to better understand the constraints under which medical device design and development take place. These structural features were shared by other activating mutants of the hLHR. Such key benchmarks as similar geographic locality, community of providers, accreditation standards, expert testimony, and res ipsa loquitur are explained. Ferrofluids exhibit unusual hydrodynamic effects owing to the magnetic nature of their constituents. We previously presented FEATURE, a method for describing microenvironments around functional sites in proteins. 3 checklists you can use today: -hospital monthly, -hospital accounting, -purchasing inventory and control.

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Within the hypothalamus, numerous LHRH-immunoreactive like (IL) cell bodies were found mainly in the ventral portion of the infundibular nucleus close to the median eminence and at a lower extent in the medial preoptic area. The device consists of a cross injector, two operation regions, and separate outlets where the analytes are collected. But, high IOP is not diagnostic nor does normal value exclude the disease. BodiMojo: effective Internet-based promotion of positive body image in adolescent girls. Multivariate Hawkes process models of the occurrence of regulatory elements. A leftward shift in the dose-response curve was observed following WIN55,212-2 relative to morphine treatment. We also compared the embryonic thermal tolerances according to six postulated reproductive modes of the study species. The peritoneal elimination of total homocysteine primarily depends on the plasma total homocysteine concentration.

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Otosclerosis patients that underwent primary stapedotomy surgery. Regulation of protein kinase C delta by estrogen in the MCF-7 human breast cancer cell line. Similar results have been achieved for polymer-coated graphene ribbons. The lack of homology between tlyA to tlyC translated sequences and the purified beta-hemolytic toxin sequence resulted in the study that is reported here. Sleep apnea, sleep disturbance, and fasting glucose variability: a pilot study. The segmentation results obtained by combining HypoCS and HyperCS yield high F1-Score of 0.86 and 0.89 with re-spect to the ground truth. Air embolism during surgery in the sitting position: its prevention, detection, and treatment.

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Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine. The protective effects of IP on mitigating acute lung injury induced by lower limb I/R are mediated by HO-1. Instead, mean body temperature seemed to be the determinant of general thermal sensation in these conditions. Genomic DNA was extracted from blood samples recovered from liquid nitrogen storage. High-dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin lymphoma. In the range of concentrations tested, which are representative of electroplating industry wastes, the main part of the toxicity can be attributed to copper and to cadmium-copper synergy. The use of IMRT was associated with excellent local control and did not result in excess PF failures outside of the TB.

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IMRT planning was performed for both CT sets using 15 MV photon beams. The technique consisted of a medium-to-large precut along the midline, above the papillary elevation, using either the common channel or the pancreatic duct in the ampulla of Vater as a guide. Amlodipine prevents apoptotic cell death by correction of elevated intracellular calcium in a primary neuronal model of Batten disease (CLN3 disease). Test images and two phantoms--one low-contrast phantom and one line-pair resolution phantom--were used to evaluate the digital system. Physical properties of solid dispersion of a nonsteroidal anti-inflammatory drug (M flagyl 250 mg pour chien -5011) with Eudragit E.

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NMDA receptor subunit and syntaxin proteins were analyzed with Western blotting. Inasmuch as this association applies to methamphetamine (MA) abuse, an understanding of the course of MA withdrawal symptoms may help to direct treatment for MA dependence. The goal of the present study was to investigate whether influenza infection was a risk factor for AF. Removal of nitrogenous compounds by catalytic wet air oxidation. Heterogeneity in actionable molecular aberrations was observed, suggesting that multi-assay molecular profiling and individualizing treatment merits investigation. Taken together, our results indicate that Chlamydia infection elicits the production of ROS, which is dependent on LMP at least partially, followed by induction of host-cell necrosis. Recently, papers suggest that the increased cholinergic tone in the heart by cholinesterase inhibitors has a positive effect on some cardiovascular disorders such as heart failure.

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The large size (36 kb) of MudP and MudQ is a favorable trait for duplication formation, probably because homology length is a limiting factor for the central crossover. The experiences of two dental Total Purchasing Pilots are used to describe where the dental profession now stands in relation to current NHS developments. Here, we investigate empirically whether it is possible to quantitatively predict future conflict in small teams using parameter-free models of social network structure. Adolescent interventions fall into 3 main categories: biomedical, behavioral, and structural. The aim of this study was to test whether sevoflurane, which is increasingly used in neuroanaesthesia, affects mitochondrial function in the central nervous system by altering the mitochondrial membrane potential (DeltaPsi(m)). Haloperidol (1 mg/kg IV in cold experiments and 0.2 mg/kg IV in LPS experiments) did not reverse ear pinna vasoconstriction, or affect body temperature. Change of the names Haloanaerobiales, Haloanaerobiaceae and Haloanaerobium to Halanaerobiales, Halanaerobiaceae and Halanaerobium, respectively, and further nomenclatural changes within the order Halanaerobiales. Comparisons between genetically identified maternally expressed genes in Drosophila and maternal mRNAs biochemically characterized in other species are made when possible. Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology.

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A structure/activity analysis with structurally similar compounds approved by the US Food and Drug Administration revealed a defined pharmacophore for inducing neuronal autophagy. Due to its broad applicability and proven validation across multiple foot and ankle pathologies, the FAOS represents a patient-centered outcome measure that can be reliably used for the assessment of patients with hallux rigidus. After microwave treatment, there was little change in the surface max daily dose of ambien microstructure but the epidermis was of uneven thickness and the four outer layers of the cuticle were thinner. Virulence factor profiles were determined by multiplex polymerase chain reaction, probe hybridization, and hemagglutination testing. Among these are a series of diamines and polyamines, as well as the diaminodisulfide cystamine. We investigated brain samples of patients with multiple sclerosis (MS) and controls with immunohistochemistry using monoclonal antibodies (MoAbs) against canine distemper virus (CDV) and measles virus (MV) proteins.

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Cancellous screw fixation is a relatively safe and useful operation. Consequently, there may be interference of cellular functions, breakdown of immune cost of detrol la 4mg tolerance and induction of autoantibodies towards the resulting neoantigens. In this review, the current strategies of antifungal prophylaxis are discussed. Comparative pharmacokinetics of the organophosphorus insecticide chlorpyrifos and its major metabolites diethylphosphate, diethylthiophosphate and 3,5,6-trichloro-2-pyridinol in the rat. It has the added benefit of being brief, with average administration time of 46 minutes for an inpatient sample and 36 minutes for an outpatient sample. Using religious orientation paradigm, this twofold study examined the relationship between euthanasia attitude and religiosity, and compared single-item and multi-item scales of euthanasia attitude. We treated 75 patients with benign bone tumours by curettage and filling the defect with calcium hydroxyapatite (HA). The method developed was successfully applied to the analysis of short chain aldehydes in 30 typical LFC excipients. Hydrocellular foam dressings can be effectively used in the management of many acute and chronic wounds.

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Rhesus macaques dose oxytetracycline in chickens were exposed to x-irradiation during the first trimester of development to disrupt neurogenesis. Glycogen level in pinealocytes at 09:00 to 10:00 showed bimodal seasonal changes, with lower levels in fall and spring and higher levels in winter and summer. In contrast to MyD88 deficiency, double deficiency of TLR2 and TLR4 -- despite the two receptors being activated by specific endogenous molecules associated to danger and signal through MyD88 -- altered neither immune response nor extent of tissue lesion size on injury. Lysine-specific gingipain K and heme/hemoglobin receptor HmuR are involved in heme utilization in Porphyromonas gingivalis. As a result, the diagnosis of BAC has been used in association with small, solitary, and well-differentiated adenocarcinoma as well as tumors with advanced clinical stage. In all the cases tested, the two methods showed a virtually identical antigen distribution. The present communication reports investigations into the effect of MIC on brain cells in culture. Rings may represent a conserved functional theme exhibited by diverse molecular systems and have implications for the understanding of the axon in development, maturity, and disease. Infectious causes have been associated with secondary HLH, with viruses being the most common. To develop experimental approaches to detection of inactive forms of Helicobacter pylori (HP) in patients treated for gastroduodenal ulcer, to try the role of such HP forms in emergence of ulcer recurrences.

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The prevalence and incidence of MG were consistent with those of previous studies. Immunohistochemistry assay and in-situ nucleic acid hybridization were carried out to analyze the protein and mRNA expression of DR-nm23 in patient samples. This paper provides a brief review of the radiochemistry of radiopharmaceuticals used in positron emission tomography (PET). Rodent and primate studies have strongly demonstrated that combining cortical stimulation (CS) with skilled motor rehabilitative training enhances functional motor recovery following stroke. Direction selectivity in the visual system of the zebrafish larva. In cases of cervical incompetence, the Shirodkar procedure is occasionally necessary when the McDonald procedure cannot be used due to poor cervical anatomic conditions. Mutational analysis of CP gene revealed a novel homozygous mutation in exon 18, resulting in prematurely truncated W1017X protein. The mutant mice lacking TLCN had no detectable abnormalities in their neural development and synaptic structures. We developed four spectrally distinct near-infrared FPs--iRFP670, iRFP682, iRFP702 and iRFP720--from bacterial phytochromes.

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Three patients presented with recurrent fever for more than nine months and in two of these cases, delay before diagnosis was long because repeated blood cultures were sterile. Differential expression of manganese peroxidase and laccase in white-rot fungi in the presence of manganese protonix medication dosage tablets or aromatic compounds. Radiographs are a diagnostic tool, widely used in dental practices, hospitals and other health disciplines. Biochemical response of Norway spruce (Picea abies (L.) karst.) towards 14-month exposure to ozone and acid mist: part II--Effects on protein biosynthesis. cerevisiae yeast directly applicable for the production of cellulosic ethanol with substantially improved productivity and yield, without of the need to use genetically modified microorganisms. In conjunction with modern methods of phalloplasty, a two-stage reconstruction of the entire phallus, including a functioning urethra, can be performed by combining the bladder wall flap with a modern (axial vessel) abdominal or groin skin flap. Evaluating children with otitis media for bacteremia or urinary tract infection. Frequency of individuals shorter than the CDC-1st centile and shorter than an empirically defined 1st centile. Large-Scale Analyses of Angiosperm Nucleotide-Binding Site-Leucine-Rich Repeat Genes Reveal Three Anciently Diverged Classes with Distinct Evolutionary Patterns.

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Among all reported cases of intravenous leiomyomatosis, this patient and another were the oldest at 72 years old, severe calcification of intravenous leiomyomatosis was infrequent, and the delay (30 years) from hysterectomy to removal of the intracardiac tumor was the longest. A series of alanine mutants within the three cytoplasmic loops of rhodopsin were expressed in HEK-293 cells, reconstituted with 11-cis what is 800 mg motrin -retinal, prephosphorylated with rhodopsin kinase, and examined for their ability to bind in vitro-translated, 35S-labeled arrestin. The epithelium in the mesonephros-derived tissues, including rete testis and epididymis, appeared to exhibit a higher capacity to express AR than the rest of the testicular tissue. A 12 kDa protein in chicken serum antigenically cross-reactive with, but unrelated to, beta 2-microglobulin. Additionally, we show that the SUN domain of Sun2 is localized to the periplasmic space between the inner and the outer nuclear membranes. Femtosecond laser-assisted corneal surgery may provide a more precise and safer approach to corneal surgery. Pure virus-associated symptoms may be treated with intermittent beta-2 agonist or anticholinergics by inhalation. However, use of a large number of geometry voxels in MCNP only slightly affects the speed of the calculation. Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells.

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