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Alpraquil (Alprazolam)
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Alpraquil

Alpraquil is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpraquil, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpraquil is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Alfix, Alpradol, Alpramax, Alpron, Alprosym, Alzep, Anzal, Belfa, Benzolam, Calmef, Cooltime, Endolam, Flunix, Fluprax, Fluxozam, Restyl, Samitol, Silam, Somaspas, Tenan, Trazopin, Trustin, Xylonite, Zolark

Similar Products:
Trandate, Prometrium, Aricept, Priligy, Prograf, Floxin, Pamelor, Zantac, Bacfen, Sumet, Vestil, Norex, Diarlop, Citalent, Clomiprop,

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpraquil dosage information

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpraquil XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpraquil XR dosage information

Side effects

The most common side effects associated with Alpraquil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Calcium current inactivation in identified neurones of Helix aspersa. Determination of methoxyl and ethoxyl groups in organic compounds in micro, decimilligram and centimilligram scales. A Multivariate Analysis on the Sedimentation of Aqueous Silica Suspensions as Studied by Means of Time Domain Dielectric Spectroscopy. These results show strong support for the hypothesis that IgE class switching occurs locally within the nasal mucosa of subjects with seasonal allergic rhinitis and that this response can be inhibited through strategies directed against local IgE production. Airway pressure release ventilation (APRV) is a mode of mechanical ventilation, which has demonstrated potential benefits in trauma patients. So, Dok-4 and Dok-5 molecules constitute a new group of adapter proteins in T cells, requiring further functional analysis. To study the role of myf5 in vivo, we generated transgenic mice harboring the bovine homolog, bmyf, under control of the murine sarcoma virus promoter.

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Starting out - It was a surprise and an inspiration to meet someone unafraid of dying. Information comprising invasive haemodynamics, TEE measurements, and 12-lead ECG was obtained on arrival of the patient in the intensive care unit (ICU), and then hourly in the ICU for 5 h. Recently, percutaneous transluminal angioscopy has been clinically used. Guaiacol oxidation has been considered to be a more reliable method than the iodide one, especially when the substrate concentration and temperature vary, and when the activity of relatively rich in protein samples, as well as of some other substances that might interfere with the I3- formation, are going to be measured. National death rates from 1916 to 1979 are presented by sex, age and 2 broad social-class groups covering manual and non-manual occupations. The comparison of the free and bound conformations of the RNA shows that two universally conserved residues of the A site of 16 S rRNA, A1492 and A1493, are displaced towards the minor groove of the RNA helix in presence of antibiotic. Hepatitis viruses A, B, C, D and E are all well-characterized, molecularly defined agents with unequivocal disease association. Reduction of methylglyoxal in Escherichia coli K12 by an aldehyde reductase and alcohol dehydrogenase.

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Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53. The relationships among TP level, TNM classification, histological subtypes, V factor and prognosis, and of tumour TP to normal tissue TP levels were investigated. Additionally, a density functional theory (DFT) investigation explained the stability of the pesticide at pH 7 and the high reactivity of the pesticide in alkaline medium. Studies use recombinant inbred mice to demonstrate that BHR in mouse models of asthma is associated with a genetic alteration at the IL-9 locus, where IL-9 expression in lung is strongly associated with bronchial responsiveness. The aim of this study was to investigate the predictors of successful MTX treatment. Measurements were performed adding spherical correction to test the different foci of the IOL.

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Despite the expense, despite the frustration, and beyond the pain of failure and uncertainty, we are compelled to employ our current knowledge if we are not to waste the many young people who can be brought to productive adulthood through hospital treatment. There are several clinical challenges for the treatment of intractable cardiovascular diseases, including restenosis, atherosclerotic complications resulting from plaque rupture, severe tissue ischemia, and heart failure. These interactions can be regulated by various effector molecules including chemokines, growth factors, and other cell surface proteins by a mechanism termed inside-out signaling of integrin function. Faecal isolates had the highest percentage of resistance, especially to high level-gentamicin, ciprofloxacin and norfloxacin. Apart from this exception, endourological techniques often represent the most appropriate therapeutic solution, but they are associated with significant morbidity. Cefepime is a fourth generation cephalosporin with the gram-positive activity of cefotaxime and the gram-negative spectrum of ceftazidime. Development of an algorithm to predict serum vitamin D levels using a simple questionnaire based on sunlight exposure. The multi-domain structure of protein maxolon nausea medication disulfide isomerase is essential for high catalytic efficiency. This study was performed to evaluate the role of HGV infection in patients with acute posttransfusion hepatitis in Taiwan.

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The low abundance of renin in brain, spleen, lung and thymus compared to kidney, adrenal, heart, testes, and submandibular gland may suggest that there are both tissue renin-angiotensin systems (RAS) and nonrenin-angiotensin systems (NRAS). Using a simplified human immunodeficiency virus type 1 p24 antigen assay to diagnose pediatric HIV-infection in Malawi. On the other hand, tyrosine phosphorylation and activation of tyrosine kinases including Syk have been shown to play a critical role in the induction of platelet responses to thrombin stimulation. Among aerobic Gram-positive bacteria, the isolation rate of Enterococcus faecalis was the highest, followed by that of Staphylococcus aureus from postoperative infections. A new antithrombotic strategy, the selective inhibition of coagulation factors, and its importance to the orthopedic specialist. Direct interaction of the EpsL and EpsM proteins of the general secretion apparatus in Vibrio cholerae. Evaluation of metabolic risk marker in obesity-related glomerulopathy. Suicidal behaviors in adult psychiatric outpatients, I: Description and prevalence. These differences may contribute to the different immunogenic properties of the two basement membranes reported in the literature.

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Bolus-chase MR digital subtraction angiography in the lower extremity. The present results are indicative of cleavage of the Fe-S bond in the nNOS mutants in their ferrous-NO state and imply a significant role of the conserved tryptophan in stabilization of the Fe-S bond. Nature and biological role of the lymphocytosis developing in bone marrow hematopoietic tissue when locally irradiated. Molecular simulation of cyclohexanyl nucleic acid (CNA) duplexes with CNA, DNA and RNA and CNA triloop and tetraloop hairpin structures. We have demonstrated that NO participates in hypoxia/reoxygenation (H/R) injury in isolated rat proximal tubules (PT) suspensions. The results of these studies showed that the problem of drug resistant tubercle bacilli is sizable and important. The dose to water energy response, that is, the dosimeter reading per absorbed dose to water relative to that for 60Co gamma-rays, was estimated for each beam quality. During a 10-y follow-up, incident type 2 diabetes cases were identified in 54 men and 102 women from a nationwide register. Oral combined treatment of diabetes mellitus (chlorpropamide--phenethylbiguanice).

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We analyzed total RNA in muscle specimens from six patients who had one of three pathogenetic point mutations in the mitochondrial tRNA(Leu(UUR)) gene, including A3243G, T3271C, and T3303C. This article reports our use of intraoperative sonography to guide in real time, the removal of radiolucent foreign bodies from five patients. Morphology of the reparative process in the urinary bladder following plastic surgery with a lyophilized homograft. Proline-rich cytokine from neurosecretory granules: a new natural substrate for dipeptidyl peptidase IV. The use of intramuscular cefoperazone versus intramuscular ceftriaxone in patients with nursing home-acquired pneumonia. Expression of cyclin-dependent kinase 5 and its activator p35 in rat brain after middle cerebral artery occlusion. Cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts ((6-4)photoproducts) are the two major classes of cytotoxic, mutagenic and carcinogenic DNA photoproducts can i consume alcohol while taking bactrim produced by ultraviolet light irradiation of cells. Large amounts of cytokines and chemokines were released in the coculture supernatants.

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