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Alprozam (Alprazolam)
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Alprozam

Alprozam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprozam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprozam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Actirax, Alcicalm, Alparazole, Alpose, Alprine, Alprop, Anzal, Aryalam, Azicalm, Azoslip, Belfa, Besquil, Diprex, Fledore, Mentolift, Nitril, Notens, Plaxid, Prozolam, Pyrex, Sertamax, Serxanti, Sinzolam, Somnirest, Zedep, Zodia, Zotin

Similar Products:
Desyrel, Cordarone, Lasix, Ventolin, Fasigyn, Diamox, Buspar, Nitrofurantoin, Finster, Cetiminic, Tricef, Zydero,

Also known as: Alprazolam

Description

Alprozam (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alprozam is used to treat anxiety disorders and anxiety caused by depression.

Alprozam is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alprozam on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprozam XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprozam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprozam XR dosage information

Side effects

The most common side effects associated with Alprozam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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This technique allows the complete and unequivocal assignment of all heme resonances, including methylene resonances of the propionic groups, directly implicated in the pH dependence of the redox properties of cytochrome c551. Postprandial dyslipidemia: a risk factor for coronary heart disease. Biologic markers are familiar tools for monitoring human absorption of, and reaction to, potentially toxic chemicals. However, current distributions using multiple pathways are largely determined by electrode type and location. Tag1 is an autonomous transposable element (3.3 kb in length) first identified as an insertion in the CHL1 (NRT1) gene of Arabidopsis thaliana. The thyroid gland is not present at birth in marsupials and thyroid function begins during the latter half of pouch life. To further understand this hormonal control, we studied the short-term regulation by cyclic adenosine monophosphate (cAMP) of the glucose-6-phosphatase (G6Pase) enzyme, which catalyzes the last reaction of EGP. Proton nuclear nagnetic resonance characterization of heme disorder in monomeric insect hemoglobins. We evaluated trends in Hib disease associated with licensure of Hib conjugate vaccines. We evaluated the efficacy and safety of a novel intradermal injection device, the MicronJet600(TM) microneedle, compared with conventional injection in terms of skin reactivity to the TST.

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To evaluate whether introduction of treatment alternatives would improve compliance with hormonal replacement therapy (HRT) as primary osteoporosis prevention in women not tolerating the first line osteoporosis prevention schedule. Intake of sugar-sweetened beverages (SSBs), which are the main dietary source of added sugar, has been shown to interact with genetic factors in affecting CAD risk factors such as obesity. The American Antarctic Ridge will take advantage of the MAR/SWIR duel by capturing an approximately 70-kilometer stretch of MAR, whereas the Antarctic plate will increase its size. Biochar affects soil organic matter cycling and microbial functions but does not alter microbial community structure in a paddy soil. Myristicin markedly suppressed LPS/D-GalN-induced enhancement of serum TNF-alpha concentrations and hepatic DNA fragmentation in mice. The effect of alcohol exposure and hypoxia on the heart rate orienting response and RSA development was studied in preweanling rats. Structural characterization of lipid membranes from clear and cataractous human lenses. Empathizing and systemizing were assessed using the Combined Empathy Quotient-Child (EQ-C) and Systemizing Quotient-Child (SQ-C). The gene coding for the Mycobacterium tuberculosis homologue of LexA has been cloned and sequenced.

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Salicylic acid treatment significantly reduced the clinical score of eyes and bacterial load in eyes during microbial keratitis but had no effect on numbers of infiltrating neutrophils. Ensuring HL7-based information model requirements within an ontology framework. Soluble glucan protects against endotoxin shock in the rat: the role of the scavenger receptor. Conventional ultrasonographic evaluation (grey scale and Doppler) represents the first line investigation in the acute pathology of the scrotum. We hypothesized that either local endogenous nitric oxide (NO) synthesis or local reactivity to endogenous NO might be impaired in patients with IDDM and that this may contribute to the development of diabetic retinopathy. Transient high affinity binding of tissue factor pathway inhibitor-factor Xa complexes to negatively charged phospholipid membranes. Midodrine hydrochloride, an alpha-agonist, could improve orthostatic BP by increasing vasomotor and venomotor tone. This illustrates the negative motivational properties of morphine withdrawal or the establishment of psychic dependence on the drug.

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The purpose of this study was to elucidate the efficacy and safety of a low dose, fractional administration of CPT-11 and cisplatin that is principally based on recently acquired knowledge of the synergistic antitumor activities between these two agents. These conformational modifications were found to be fast and fully reversible and required only low oxidation potentials. European society of cardiology (ESC) guidelines recommend that cardiovascular disease (CVD) risk stratification in asymptomatic individuals is based on the Systematic Coronary Risk Evaluation (SCORE) algorithm, which estimates individual 10-year risk of death from CVD. An empirical approach using factor and cluster analyses and conjunctive decision rules. Cervical cancer patterns with automation-assisted and conventional cytological screening: a randomized study. The primary treatment for obstetric sphincter injury is overlapping sphincteroplasty.

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Snapping shoulder caused by glenoid labral bone apposition: A case report. These results suggest that the activation of MrgC receptors can relieve pain hypersensitivity by the inhibition of nNOS increase in DRG neurons and microglia activation in the spinal dorsal horn in the early time following peripheral nerve injury. Eimeria acervulina infection in the chicken: a model system for estimating nutrient requirements during coccidiosis. LPI is a common event in colonic cancer and is a consistent predictor of subsequent intraperitoneal recurrence. Trazodone for the treatment of neuroleptic-induced acute akathisia: a placebo-controlled, double-blind, crossover study. The human gene transcript and the corresponding proteins were detected in a cell subset of the medial habenula. However, whether these increases in MOR-IR are restricted to certain cell types or cellular compartments (i.e., presynaptic, postsynaptic, or glial profiles) has not been determined. Therion Biologics, in collaboration with Aventis Pasteur, is developing ALVAC-CEA/B7.1, a recombinant, pox virus-based vaccine that targets carcinoembryonic antigen (CEA) found on the surface of lung and colorectal tumor cells, for the potential treatment of lung and colorectal cancer. Separating distractor rejection and target detection in posterior parietal cortex--an event-related fMRI study of visual marking.

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Polypharmacy is associated with an increased risk of inappropriate use of medicines and drug-related problems. Hepatic transplantation has previously been reported in the treatment of hereditary amyloidosis associated with variant transthyretin proteins, which are mainly synthesized in the liver. Metformin improved the glucose rate and the homeostasis model assessment-insulin resistance (HOMA-IR) index and caused partial reversion of ovaries and uterine morphology in female rats androgenized with testosterone. An investigation has been carried out into the formation of dilated lateral intercellular spaces in the medullary collecting duct of the rat kidney following water deprivation or infusion of vasopressin. Whether the potential of HMG-CoA reductase inhibitors to prevent AGAS is due to their lipid-lowering effect, immunomodulating properties, or a combination of both is also not completely known at present. In 51 patients the ECG and left pulmonary end-diastolic pressure (LPEDP) were investigated additionally at rest and during exercise (bicycle ergometre).

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The heart is located centrally in our body, and its pumping motion demands the attention of the observer. Neuroimaging and patient research has emphasized the importance of left inferior frontal gyrus (IFG)--however, impaired semantic control can also follow left temporoparietal lesions, suggesting that this function may be underpinned by a large-scale cortical network. Targeted proteomics identify metabolism-dependent interactors of yeast cytochrome c peroxidase: implications in stress response and heme trafficking. Arthroscopic subacromial decompression and postoperative management. Reactive hyperemia was significantly less in PVD than in controls. Regulation of beta-lactamase synthesis as a novel site of action for suppression of methicillin resistance in Staphylococcus aureus. Construct validation of measures of three kinds of experimental fatigue. Generation of a monoclonal antibody specific for ganglioside GM4: evidence for GM4 expression on astrocytes in chicken cerebellum. Arguments, based on biological and anatomical characteristics are put forward regarding Schistosoma hippopotami Thurston, 1963 as synonymous with Schistosoma mansoni.

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Theophylline-associated status epilepticus resulting in quadriplegia. One of these developments is the reworking of the concept of generalized anxiety disorder (GAD) from that of a residual category (anxiety after all other anxiety disorders are removed) to a generalized anxiety syndrome that includes symptoms of mild depression that are less severe than the symptoms of anxiety. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. The influence of the time interval (TI) between drug administration and laser activation on selectivity of meta-tetrahydroxyphenylchlorin(mTHPC)-mediated photodynamic therapy (PDT) for tumour tissue was assessed in BALB/c nude mice bearing human malignant mesothelioma xenografts. AUM was capable of forming crystals and encrustations resembling those found in natural urinary tract infections. A new treatment principle in the therapy of postoperative paralytic ileus. The region from intron 4 of the last genes, to the nearest neighbor gene, TEX28, was also efficiently amplified by the long-range PCR and the gel-purified products (27.5 kb) were used as the template in the second PCR for exon 5. We examined the phylogenetic relationships among five heterothallic species of Neurospora using restriction fragment polymorphisms derived from cosmid probes and sequence data from the upstream regions of two genes, al-1 and frq. Acid fast bacilli positive on Ziehl Neelsen stain were labeled as mycobacterial infection possibly tuberculosis. Together, our data suggest that encoding and retrieval in episodic memory depend on the interplay between domain-specific structures, most of which are involved in memory as well as perception, and domain-general structures, some of which operate more at encoding and others more at retrieval.

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The patient was a 75-year-old male who had a right empyema with bronchopleural fistula, which had developed after right upper lobectomy for pulmonary tuberculosis performed 18 years previously. We demonstrated that vMyx-M011L-KO induces apoptosis in BTICs, dramatically increasing sensitivity to the virus. Sunrise at the synapse: the FMRP mRNP shaping the synaptic interface. Trypan blue staining was seen in all three types of lesion, with both the neuropil and some neurones being stained. Pattern of Pseudomonas aeruginosa drug resistance in Tabriz Children Hospital. RFLP typing with transmembrane probes detected significantly less polymorphism than typing with cDNA or exon probes. One group of bars was invested with gypsum-bonded investment and the other group invested with phosphate-bonded investment. Erectile impotence has been a problem for the patient and a frustration for the physician since the beginning of medical history. Functional magnetic resonance imaging of internet addiction in young adults. Three veins were severely kinked as they descended lamivudine medication across the transverse process of the atlas.

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Transport of radiolabelled cholyl-L-Lys-epsilon-tBOC ester and cholyl-D-Asp-beta-benzyl ester was inhibited by taurocholic acid. This project includes a more formal means of communicating QI interventions. results suggest that the protective effect of HP on myocardial contractile function may be mediated by receptor(s) that can you take tylenol with etodolac 400 mg can be inhibited by low concentrations of antagonist but may not have a primary role in the reduction of cellular damage by HP in rats. Similar filopodial processes are present less conspicuously among cells in the margin of the area pellucida. Children living with epilepsy in the developing world are faced with challenges of lack of access to appropriate diagnostic evaluation and a high risk of misdiagnosis and inappropriate therapy. Outcome was the following: 4 were aborted, 1 died neonatally, and 13 survived.

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