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Alrif (Alprazolam)

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Alrif is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Aaram, Alpam, Alpranex, Alpraquil, Alprax, Alpron, Alprotame, Alprowon, Altin, Alzoact, Alzopax, Berest, Cozac, Depoxit, Destres, Enxolam, Fluwel, Kaprolam, Mebrin, Paxor, Plxna, Restam, Richpram, Setlan, Sinaday, Wycalm, Zocam

Similar Products:
Azulfidine, Differin, Lanoxin, Ovral, Glucotrol, Zithromax, Daklinza, Allynol, Theosol, Cardules, Gabamec, Oseben,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alrif. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alrif XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alrif dosage information

Side effects

The most common side effects associated with Alrif are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Alrif if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Alrif is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Alrif while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Alrif is not approved for use by anyone younger than 18 years old.

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Acute myocardial infarct and coronary artery aneurysm during pregnancy. We have explored the relationship between Axin and Dvl-2, a member of the Dishevelled family of proteins that function upstream of GSK-3beta. The human histiocytic lymphoma cell line U937 can be induced to differentiate along the monocyte/macrophage pathway by either phorbol myristate acetate (PMA) or by the combination of retinoic acid (RA) and 1,25-dihydroxyvitamin D3 (VD). The nurses collected information from the medical records and asked study subjects to complete the Beck Depression Inventory questionnaire during their stay in hospital and using a mailed questionnaire 30 days, 6 months and 1 year later. Intralobar and extralobar bronchopulmonary sequestration complicated by Nocardia asteroides infection. The qualitative data served to temper the positive quantitative outcome data in showing that mothers are dependent on the food program. Thus, combination of FISH with the comet assay or MN test proved to be promising techniques for evaluation of the distribution of DNA and chromosome damage in the entire genome of individual cells. The etiopathogeny of gastrointestinal infections in newly imported monkeys with special emphasis on associated parasitic and bacterial infections. We confirmed TSA-mediated activation of the JC virus promoter in the context of natural chromatin structure in stable cell lines. Data from invasive hemodynamic monitoring, radionuclide cineangiography, and echocardiography were also reviewed.

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IgA antibodies to human immunodeficiency virus in serum, saliva and urine for early diagnosis of immunodeficiency virus infection in Ugandan infants. A study on the relationship between Lp(a) and arteriosclerotic cerebral infarction. A literature study shows that 100 years ago was the time in which the veterinarians get at first the possibility to noroxin pills side effects work with synthetic antiinfective, antipyretic, laxative and anesthetic drugs. Eighty percent of the patients had palpable distal pulses observed at follow-up examination. The ratios of nonsynonymous substitution resulting in various forms of physicochemically radical and conserved amino acid change were shown to be largely equal throughout these different parts of the protein. A phased laboratory evaluation similar to that suggested by Ogborn and Crocker facilitates in the evaluation of secondary hypertension.

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Impact experiments of an external hip protector in young volunteers. The clinical features of pediatric GBS differ from those of adults. To our surprise, an important regulator, Ras was not efficiently activated to a significant level in response to VEGF. A number of genes, such as RHO, PDE-beta, RDS, TIMP3, MYO7A, RETGC1, RPGR, CRX and ABCR, are now known to be particularly important. On magnetic resonance (MR) images, EMC was a lobulated mass with high signal intensity on T2-weighted images and enhancement with low-signal-intensity focal areas on contrast-enhanced T1-weighted images. Tracheal temperatures were recorded from a Trachelon tube inserted approximately 21 cm. To identify new Z-linked genes, total RNA from reciprocal hybrid females between the silkworm strains p50 and C108 was compared using the differential display technique. The protein p53 is a universal tumor suppressor in humans and negative regulator of cell proliferation, which is induced in cells in response to the damage of DNA and controls arrest of the cell cycle at specific checkpoints. Functional vif, vpu, and vpr genes were dispensable for virus replication from transfected DNA, but intact nef provided a detectable enhancement of early viral gene expression and promoted maintenance of HIV-1 infection. To determine whether exaggerated natriuresis and exaggerated renal sympathoinhibition during volume loading constitute an intermediate phenotype in spontaneously hypertensive rats.

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