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Altiazem (Diltiazem)

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Altiazem works well for chest pain caused by poor blood flow to the heart. Altiazem is a calcium channel blocker that slows your heart rate and relaxes your blood vessels. This gets more oxygen to the heart so it doesn't have to work as hard to pump, which relieves chest pain.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Xanax, Catapres, Pyridium, Anafranil, Medrol, Epivir, Sovaldi, Paxil, Altace, Enaril, Kezop, Torid, Domiv, Mycosyst, Piosafe, Eptanol, Aristrol, Floxelena, Tinapax,

Also known as: Diltiazem


Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Altiazem LA. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Altiazem LA dosage information

Side effects

The most common side effects associated with Altiazem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of diltiazem in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving diltiazem.

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Significance of hepatic arterial responsiveness for adequate tissue oxygenation upon portal vein occlusion in cirrhotic livers. Age- and procedure-specific rates of general surgery were obtained from the National Hospital Discharge Survey and National Survey of Ambulatory Surgery. They find expression in a variety of staff behaviors in anxiety and defensiveness about treatment, in staff ambivalence about the value of methadone, and in extreme cases, in cynical and suboptimal treatment practices. the most promising conditions for a monoclonal antibody variant separation. Injection sclerotherapy for variceal bleeding in patients with irresectable hepatocellular carcinoma.

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Artemia nauplii challenged with a fluorescently labelled highly pathogenic strain (IPEY54) showed patches in the digestive tract. Detection of experimental thrombi in rabbits with an 131I-labelled fibrin-specific monoclonal antibody. Some of these measures are discussed according to the commonly accepted classification of wounds. Does continuity of carer matter to women from minority ethnic groups?. We report the results of experiments on video microscopy recordings and three-dimensional confocal animations of biological specimens to evaluate the compression efficiencies of the principal video compression-decompression algorithms (codecs) and to document the artefacts associated with each of them. In addition, hemolysis is associated with surgical procedures, hemodialysis, blood transfusion, and other conditions in which mechanical forces can lead to red blood cell rupture.

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Randomised clinical trial comparing a 12 week programme of either drop squat exercises or leg extension/leg curl exercises. To examine the results of lacrimal bypass surgery in patients with sarcoidosis. In both cases pregnancy were ended by cesarean section: in first case due to obstetric indications, in second due to neurological indications. Hypoxia from hypoventilation and low levels of inspired oxygen appeared to be the chief cause of cardiac arrest in this study. Postoperative assessments were conducted every 6 h for the first 48 h after surgery. Cytochrome c in cytosolic fraction was determined using a human cytochrome c immunoassay. Thus, catalase appears to have a novel protective role(s) against electrophile toxicity. Delay and probability discounting among payday and title loan recipients. This study examines whether self-efficacy is a mediator in the association between occupational social class (OSC) and emotional symptoms. Genetic evidence that the yopA gene-encoded Yersinia outer membrane protein Yop1 mediates inhibition of the anti-invasive effect of interferon.

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The present investigation was done to elucidate the role of cAMP-response element-binding (CREB) protein in this system. Nonmelanoma skin cancers (NMSCs), the most common malignancy in kidney transplant recipients (KTRs), are more frequent and aggressive in KTR than in the general population. The search of bibliographic databases (MEDLINE, IME, ISBN and Teseo), was completed with an extensive search of the gray literature and of unpublished studies through contact with public and private institutions which may fund such studies. Fingernails represent an attractive wearable platform, merging beauty products with chemical sensing, to enable monitoring of our surrounding environment. Literature also strongly emphasizes the role of spatial scale for the patterns of diversity and suggests that patterns are affected by species traits as well as ecosystem characteristics. Comparative molecular field analysis and comparative molecular similarity indices analysis of thalidomide analogues as angiogenesis inhibitors.

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Early and correct diagnosis of synchronous meningioma in F-18 fluoride bone scans might prevent relevant neurologic comorbidity. Stratified random sampling was utilized to obtain a sample of 2349 young adults. The results suggest that localization of KLF4 in the nucleus of breast cancer cells is a prognostic factor and identify KLF4 as a marker of an aggressive phenotype in early-stage infiltrating ductal carcinoma. Factors influencing the progesterone-induced luteinizing hormone surge in rhesus monkeys: diurnal influence and time interval after estrogen. For men, the death risk at the age of 40-69 years stagnated or increased during the first 20-30 years after 1950.

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Here we report the complex structure of the LGR4 extracellular domain (ECD) with the RSPO1 N-terminal fragment (RSPO1-2F) containing two adjacent furin-like cysteine-rich domains (FU-CRDs). Neuromedin B and C immunoreactivities have similar regional distribution in rat brain, but the content of immunoreactive neuromedin B is 2-6 times higher than that of immunoreactive neuromedin C in every region. EUS was superior to other imaging techniques in the detection, staging, and follow-up of submucosal smooth muscle tumors because of clear imaging of the intramural abnormality and adjacent lymph nodes. Recent research has implicated the lymphatic system in the pathogenesis of cardiovascular diseases including obesity and metabolic disease, dyslipidemia, inflammation, atherosclerosis, hypertension, and myocardial infarction. We describe here several of these systems and highlight some potential applications of these technologies. The cutaneous lesions were cured leaving behind scars by secondary suture after times of epluchage, and the fine nodular shadows over lungs disappeared finally. Cationic Re(V) oxo complexes with poly(pyrazolyl)borates: synthesis, characterization, and stability. In this introductory chapter we first describe the reasons why organized activities, like sports, arts, and school clubs, are ideal settings to examine peer processes. Cross-sectional study with 573 NIT-T2DM patients from 83 primary care surgeries. Distribution of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in human tissues.

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This article uses a mock curriculum design scenario as a framework for the introduction of five major learning theories. The incidence of spontaneous abortion more than doubled when the IUD remained in utero. Characteristic Schwann cells were present, with cytoplasm and elongated cytoplasmic processes coated with a basal lamina. We further evaluated this WBH protocol by performing multiple and interrupted WBH treatments. Researchers can provide the feedback needed to improve DSS cost estimates. This study suggests that AJBVFS is an appropriate scaffold for the delivery of osteogenic cells and the addition of CMC gel as a handling agent promotes osteogenic proliferation and differentiation and is therefore likely to encourage bone healing.

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During maintenance treatment, median vitamin K1 levels settled in the low normal range. Comparison of past developments in the NHS with new methods of health care organisation in the United Kingdom (UK). Our design exploits a time-dependent index modulation obtained with conventional phase modulators such as the one widely available in silicon photonics platforms. The relationships between heart rate deceleration capacity and spectral indices of heart rate variability during different breathing frequencies. Applications of electron data processing in all fields of medicine and especially in medical microbiology are increasing rapidly. Since lectins such as Con A, WGA, PHA-L, and PSA inhibited the induction of attachment, attachment-inducing proteins were suspected to be glycoproteins. New concepts in the regulation of follicle growth should permit the introduction of improved methods of ovarian stimulation, eg through the use of LHRH antagonists or growth factors. Nerve conduction could not be measured for one severely ataxic rat and the electromyogram indicated a loss of motor unit function.

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It appears to participate in morphogenetic processes leading to the formation of boundaries and substrates for early axon growth, processes which are in the end largely based on site-specific expression of cell adhesion molecules. A clear difference lies in the greater resistance of cerebral microvessels to diabetic damage. This paper describes an ongoing randomized controlled trial designed to assess the impact of genetic and environmental risk assessment (GERA) on colorectal cancer (CRC) screening. For each model, the governing differential equations were used to compute the system matrix. This study demonstrates, for the first time, the presence of both gallic acid derivatives and polysaccharides as major antioxidant principles of the aqueous extract of rose flowers. The colorimetric assay was reproducible, and its results were compared in parallel with that of the imaging analysis method. In total, 1125 female mosquitoes were collected during the hut trial, mainly Culex quinquefasciatus Say. Inhibitory activity of four demethoxy fluorinated anthracycline analogs against five human-tumor cell lines.

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The aim of this study was to purify mouse MSCs from adult bone marrow and to functionally characterise their abilities to differentiate along diverse lineages. After siRNA-mediated knockdown of c-Myb expression, the expression levels of two out of three ChIP positive Myb target genes, ADA and c-MYC, were strongly affected. Primary end points were pre-discharge hematuria necessitating the restoration of bladder irrigation or the cessation of aspirin treatment and late hematuria treated in an urgent care setting, requiring hospital admission or compelling the cessation of aspirin treatment. Here, we use multiple depolymerization methods in order to directly demonstrate that cross-linking and bundling proteins effectively suppress the actin depolymerization in a concentration dependent manner. We describe a simple method using membrane potential ramps for rapidly determining the ion-channel selectivity of drugs that affect action-potential duration in isolated cardiac myocytes.

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The vibrational bands associated with the N-H stretching mode of the free base are broader in the first electronically excited state, accessed via the Q band of protoporphyrin IX, than the corresponding bands in the ground-electronic state. In order to assess the validity of this theory, 8 dyslexic children and 14 controls were examined with a motion-onset visual evoked potential (VEP) paradigm at three different velocities (2, 8, and 16 deg/s). Women were randomly assigned to receive BD information and/or imaging technology information via 2 by 2 factorial design, and completed planned behavior measures (e.g., attitudes, intentions) related to BC screening. Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells. Coughs and headaches due to other people smoking at work enhances support for a completely theolair drug information tobacco-free campus among non-smokers.

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Clinical status and dependency of the elderly requiring long-term care in Japan. The samples are driven by ac and dc voltages that generate a dielectrophoretic potential at the ridge as well as (linear) electrokinetics. Higher linear cutting velocities and greater cutting depths independently resulted in higher forces. Hematopoietic growth factors (HGF) can suppress chemotherapy-induced programmed cell death (apoptosis) in hematopoietic cells. Partial-thickness burns in children can be effectively treated with BGC with good results, even in infants and toddlers. The impact of methadone and drug-free treatment on criminal behavior. Left ventricular dyssynchrony in patients showing diastolic dysfunction without overt symptoms of heart failure. Estrogen can reduce hepatic gluconeogenesis which could affect insulin concentrations.

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Identification of ZNF200 as a novel binding partner of histone H3 methyltransferase G9a. Complete primary structure of the human estrogen-responsive gene (pS2) product. Their evaluation before subjecting the patient to the embryo transfer may help to increase the pregnancy rate. This study demonstrates how the expression of these integrins are modulated in vitro by trace elements. Forty-seven epidemiological WEA cases were employed asthma patients treated at a health maintenance organization in the United States who completed a questionnaire and spirometry, and fulfilled criteria for WEA based on self-reported, work-related what drug class is vasotec worsening of asthma and relevant workplace exposures as judged by an expert panel. During the rare mode, the excystation vacuole breaks the thin membrane instead of the cyst wall that ruptures under the pressure of the body of the regenerating specimen.

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In vivo, whereas the size of spontaneously formed and diet-induced aortic atheromas was indistinguishable in apoE-KO and Super-p53/apoE-KO mice, the latter exhibited attenuated neointimal thickening in mechanically injured femoral artery. General dental practitioners should be aware of this phenomenon when providing care for these susceptible patients. It is concluded that repeated dose inhalation exposure of small numbers of animals is a useful mode of exposure for studying parameters that may elucidate toxic effects of air pollutants emitted from automotive engines, with a possibility to evaluate engine and fuel with regard to health hazards. Breast and prostate cancers are hormone amethopterin -sensitive malignancies that afflict millions of women and men. BOLD fMRI deactivation of limbic and temporal brain structures and mood enhancing effect by transcutaneous vagus nerve stimulation.

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Here, we describe the effects of schistosomiasis, and its treatment, on human basophil function by following changes in total cellular histamine and in vitro histamine-release induced by schistosome Ags or anti-IgE, in blood samples from infected Ugandan fishermen, who are continuously exposed to S. Biomimetic synthesis of silver nanoparticles by Citrus limon (lemon) aqueous extract and theoretical prediction of particle size. We accurately assessed the patterns of geographic distribution in actual genetic species of a marine meiofaunal animal model: Ototyphlonemertes. Serotype 6D of Streptococcus pneumoniae has been reported in Asia and the Fijian islands among nasopharyngeal carriage isolates. We investigated the clinical characteristics and cytokine profiles of patients with RA-OP treated with bDMARD or conventional synthetic DMARD (csDMARD). Except for patients with bilateral vitreous hemorrhages, early vitrectomy may not be necessary in most cases of intraocular hemorrhages associated with nontraumatic SAH. Genetic predisposition is proposed as a what drug is ticlopidine major risk factor and there are several controversial reports on the association of PCa and gene polymorphism such as the receptors of the androgen receptor (AR) and the vitamin D (VDR).

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These behavioral data suggest that early experience with a CVS facilitated the onset of escape deficit induced by a brief IS event, an effect that can be prevented by chronic DMI. Variables which predict burnout experienced by oncology clinical nurse specialists. The LPS projects a regular grid on the vocal fold surfaces and in combination with the HSC allows a three-dimensional reconstruction of the vocal fold surface. This automated methodology provides a high-throughput drug screening system for the targeting of ion channels and a data-intensive analysis technique for studying ion channel gating mechanisms. En bloc esophagectomy in patients with transmural esophageal adenocarcinoma is required to obtain the survival benefit of an R0 resection, to adequately assess lymphatic tumor burden, and to be able to predict the likelihood of recurrence and death and thereby guide the use of postoperative adjuvant therapy. Co-culturing syngeneic tumor cells and NK cells resulted in enhanced MHC class I expression on the surviving tumor cell fraction, which was less susceptible to NK lysis.

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Gender, stage, and treatment partially accounted for worsened survival in African Americans and Hispanics at all ages. The latest developments in insulin therapy will help to better manage this unique inpatient population. The systemic and renal effect of omapatrilat was evaluated and compared with that of enalapril (30 and 10 mg/kg per day) in sodium-depleted, one-kidney, one-clip hypertensive rats. The automatic movement of tabletop after protonix medication iv stability image match is satisfactory. The use of arteriovenous graft is indicated in patients if the subcutaneous venous bed is exhausted or unsuitable for arteriovenous fistula creation. Adding value to the electronic health record through secondary use of data for quality assurance, research, and surveillance. Elevated levels of EROD activity in dab were found at the two stations nearest to the incident up to three months after the spill but no clear relationship to putative contaminant levels was determined. For the set of subjects involved in the study, ocular diattenuation presented individual differences, however significant changes were not found across the different wavelengths. At autopsy the posterior pharynx was obstructed by blood clot with aspirated blood within the distal airways of the lungs, and melena throughout both small and large intestines. The flap is useful for covering wounds around the knee, as well as the proximal and the middle thirds of the leg.

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Role of frailty and sarcopenia in predicting outcomes among patients undergoing gastrointestinal surgery. Cadmium and lead concentrations in the amniotic fluid of pregnant smokers and non-smokers. Stripping of the small saphenous vein and subfascial endoscopic perforator surgery utilizing screw-type ports was successfully conducted in the prone position. A novel culture system was developed that does not use live virions and in which the APCs are monocyte-derived dendritic cells (DCs). Photoreceptor axons induce the outgrowth of these scaffold axons. We propose the names FMO 7P, 8P, 9P, 10P and 11P for these genes. No reasons based in ethical concerns have surfaced that would in any way discredit the program. This paper presents the results of the detailed energy audits of six full-scale MBRs operated by Suez Environnement in glyburide action of drug France, Spain and the USA based on on-site energy measurement and analysis of plant operation parameters and treatment performance.

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