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Apcical (Calcitriol)
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Apcical

Apcical is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Apcical is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Actical, Alcee, Alfabond, Apcical, Arcium, Aristrol, Bonestat, Calcicare, Calcikind, Calcimet, Calcit, Caldikind, Caldix, Calosto, Calsure, Caltin, Calvical, Carcal, Cholical, Dmcal, Duracal, Fovit, Lctrol, Minroset, Netxod, Nutribone, Ostonex, Primacal, Romical, Septriol, Vitalpha, Zaxial

Similar Products:
Mysoline, Sumycin, Elocon, Reminyl, Altace, Myambutol, Aygestin, Depakote, Microzide, Caverta, Sinobid, Siopelmin, Amlovas, Fexokast, Decet, Retoz, Theostan, Tetra, Alfresh, Triamtereen,

Also known as: Calcitriol

Description

Generic Apcical is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Apcical are intestine and bone. Generic Apcical receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Apcical may also act on the kidney and the parathyroid glands. Generic Apcical is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Apcical has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Apcical, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Apcical in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Apcical produces other independent beneficial effects. Apcical is also known as Calcitriol. Generic Apcical treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Apcical is Calcitriol. Brand name of Generic Apcical is Apcical.

Dosage

Generic Apcical is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Apcical suddenly.

Overdose

If you overdose Generic Apcical and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Apcical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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The purpose of this study was to examine the extent to which executive cognitive dysfunction and frontally-mediated behavioral disturbances are associated with functional impairment in patients with mild-to-moderate Alzheimer disease (AD). Neuromuscular relaxants such as pancuronium bind to M2 and M3 muscarinic receptors as antagonists. Determination of the nucleotide composition of Pasteurella multocida strains. We consider that with the development of modern neuro-imaging techniques, intensive care units, neurological monitorization, developments in neurosurgical techniques with the use of magnification, the ultrasonic aspirator and stereotactic techniques, there will be more and more patients with spontaneous intracranial haematomas who can be successfully treated surgically in the next few years. American Association of Gynecologic Laparoscopists 1991 membership survey. All the products were tested for their H(3)-antagonistic and H(2)-agonistic properties on electrically-simulated guinea-pig ileum segments and guinea-pig papillary muscle, respectively. We examined the location of the IUD in 97 normal women 45-60 days post-insertion, and in 25 pregnant women with the device in situ. Doxorubicin entrapped in sterically stabilized liposomes: effects on bacterial blood clearance capacity of the mononuclear phagocyte system.

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Resistance to doxorubicin (DOX) is mainly due to the effect of P-glycoprotein encoded by the multidrug resistance (MDR) gene. Our results show that the percentage of shunted babies was identical in treated and control patients despite the enhancement of endoventricular fibrinolysis obtained in all treated patients. Vertebrate cone and rod photoreceptor cells use similar mechanisms to transduce light signals into electrical signals, but their responses to light differ in sensitivity and kinetics. Cloning of four growth hormone/chorionic somatomammotropin-related complementary deoxyribonucleic acids differentially expressed during pregnancy in the rhesus monkey placenta. Development of macrovascular diseases in NIDDM patients in northern Taiwan. Role of Salmonella arizonae and other infective agents in enteric disease of lambs. Sections from 82 lung carcinomas, including squamous cell carcinomas, adenocarcinomas, and large cell and small cell carcinomas, as well as sections of developing and adult human lung were studied using the lectin amaranthin and a monoclonal antibody. Hemangioblastomas, which are associated with von Hippel-Lindau disease, represent the third most common type of intramedullary spinal cord tumour. A successful pediatric nuclear medicine examination can be defined as a high-quality study coupled with the child and parent feeling that their emotional needs have been considered.

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The mechanism involved in the blockade of M-current by linopirdine was studied in cultured rat superior cervical sympathetic ganglia using whole-cell patch clamp recording. We first consider the extent of genetic variation found in Schistosoma mansoni and some factors that may be contributing to this variation. Laparoscopic repair of inguinal hernias using a totally extraperitoneal prosthetic approach. In addition, the distribution of 22:6n-3 in the pellet and supernatant of diluted rumen fluid was measured. ETA and ETB receptor antagonists synergistically increase extracellular endothelin-1 levels in primary rat astrocyte cultures. Species specificity in the expression of LIF receptor as well as ligand binding may play a role in LIF signaling in these germ cells. This short communication describes a case of human conjunctival dirofilariosis by Dirofilaria immitis. Second, a molecular explantation of why Th2 cells fail to reverse phenotype in response to IL-12 may allow treatment of atopic individuals to remove the disease-promoting T lymphocyte compartment. Development of a technique for recording and transferring natural head position in 3 dimensions.

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