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Apomatine (Metoclopramide)

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Apomatine is used to treat the symptoms of gastroesophageal reflux disease (GERD) like heartburn. It is also used to treat people with slow emptying of the stomach and intestinal tract. Apomatine is available only with your doctor's prescription.

Other names for this medication:
Acimet, Actinorm, Cepar, Clomet, Copar, Cosmet, Donmet, Elinorm, Emenil, Emenorm, Maxeron, Maxinorm, Megatech, Metajex, Metcon, Metoclopramide, Metocontin, Metopar, Metoz, Metpar, Migrosh, Naushi, Nausifar, Pacimol, Paramet, Paranorm, Peripan, Peronorm, Promet, Propamid, Pymet, Rivnorm, Vomitex, Vomitran, Zerinorm

Similar Products:
Evista, Dramamine, Nimotop, Detrol, Cenforce, Adipex, Lioresal, Thorazine, Motrin, Zyloprim, Clomate, Ceter, Donogen, Exporil, Exazol,

Also known as: Metoclopramide


Apomatine (tamsulosin) is an alpha-blocker that relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Apomatine is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Apomatine is not approved for use in women or children.


This section provides information on the proper use of a number of products that contain estradiol. It may not be specific to Apomatine. Please read with care.

It is very important that you use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects.

This medicine is to be used only in the vagina. Use it at bedtime unless your doctor tells you otherwise.

This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.

To use the vaginal ring:

This medicine is contained in a ring that you or your caregiver will put into your vagina. The ring will slowly release small amounts of medicine for your body to absorb. Your caregiver will show you how to insert the ring. Do not remove the ring from the sealed pouch until you are ready to use it. Once the ring is in place inside your vagina, you should not be able to feel it. If you feel uncomfortable, the ring may not be inserted far enough. Gently push the ring farther into your vagina. If you feel pain, talk to your doctor. You will leave the ring inside for 90 days (3 months), unless your doctor tells you a different schedule. After that time, remove the ring and insert a new one. If you forget to remove the ring after 90 days, call your doctor for instructions. The ring may move down into the lower part of your vagina accidently. This can happen if you strain to have a bowel movement. Use your finger to gently push the ring back into place. If the ring comes all the way out of your vagina, rinse it off with warm water and put it back in. Call your doctor if the ring comes out several times. If you need to remove the ring, hook your finger through the ring and pull it out.

To use the Imvexxy™ vaginal insert:

The insert should be used only in your vagina. Do not swallow. Keep your hands clean and dry while handling the insert. Push an insert through the foil of the blister package and hold it with the larger end between your fingers. You may choose to put the insert into your vagina using the lying down or standing up position. Put the insert about 2 inches into your vagina, with the smaller end up, using your finger. Most women will start by using a new insert every day for two weeks, then change to using a new insert only 2 days each week. Carefully follow the schedule that your health caregiver tells you to.

To use the Vagifem® vaginal insert:

The tablet should be used only in your vagina. Do not swallow the tablet. Each vaginal tablet comes packaged inside an applicator. Do not take the tablet out of the applicator. If the tablet comes out of the applicator but has not fallen out of the package, carefully put it back into the applicator for insertion. If the tablet falls out of the applicator, throw it away and use a new applicator that still has the tablet inside it. Keep your hands clean and dry while handling the tablet. Take the applicator out of the plastic wrap before using it. Use the applicator only one time and then throw it away. Use a new applicator for each dose. Most women will start by inserting a new tablet every day for two weeks, then change to inserting a new tablet only 2 days each week. Carefully follow the schedule that your health caregiver tells you to.

To use the Divigel®:

Open the packet and use the entire contents of a packet on the skin of either right or left upper thigh once a day. Apply the gel to the right or left upper thigh on alternate days to avoid potential skin irritation. Do not apply the gel on the face, breasts, or irritated skin or in or around the vagina. Allow the gel to dry after application before dressing. Avoid fire, flame, or smoking until the gel has dried. Do not wash the application site within 1 hour after applying the gel. Avoid getting the gel into your eyes. Wash your hands after each application.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For vaginal dosage form (gel): For atrophic vaginitis, hot flashes, and other symptoms caused by menopause: Adults—At first, 0.25 grams applied on the skin of either right or left upper thigh once a day. Your doctor may adjust your dose as needed up to a maximum of 1.25 grams once a day. Children—Use is not recommended. For vaginal dosage form (ring): For atrophic vaginitis, hot flashes, and other symptoms caused by menopause: Adults—One vaginal ring inserted into the vagina for 3 months. Your doctor may adjust your dose as needed. Children—Use is not recommended. For vaginal dosage form (insert): For treatment of atrophic vaginitis caused by menopause: Adults—10 micrograms (mcg) or one insert into the vagina once a day for 2 weeks, followed by one insert 2 times a week. Children—Use is not recommended. For treatment of painful sexual intercourse caused by menopause: Adults—At first, 4 micrograms (mcg) or one insert into the vagina once a day for 2 weeks, followed by one insert 2 times a week (every 3 to 4 days). Your doctor may adjust your dose as needed. Children—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw this medicine away after you have used 120 sprays.

Detailed Apomatine dosage information

Side effects

The most common side effects associated with Apomatine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Many drugs can interact with Apomatine. There is a partial list. Tell your doctor if you are using: arsenic trioxide (Trisenox); cyclosporine (Neoral, Sandimmune); pimozide (Orap); tacrolimus (Prograf); theophylline (Theo-Dur, Theolair, Theochron); warfarin (Coumadin, Jantoven); another antibiotic, especially clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam); an antidepressant such as amitriptylline (Elavil, Vanatrip, Limbitrol), clomipramine (Anafranil), or desipramine (Norpramin); anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam); cholesterol-lowering medicines such as lovastatin (Mevacor), atorvastatin (Lipitor), or simvastatin (Zocor); ergot medicine such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray); heart or blood pressure medication such as digoxin (Lanoxin, Lanoxicaps), diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others; heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), dronedarone (Multaq), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace); HIV medicines such as nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Invirase); medicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran); medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon); migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig); narcotic medication such as methadone (Methadose, Diskets, Dolophine); a sedative or tranquilizer, such as alprazolam (Xanax), diazepam (Valium), midazolam (Versed), or triazolam (Halcion); or seizure medicine such as carbamazepine (Carbatrol, Tegretol) or phenytoin (Dilantin).

This list is not complete and there are many other drugs that can interact with azithromycin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

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To assess the efficacy and safety of bimanual microphacoemulsification combined with vitrectomy in eyes with clinically evident cataract and vitreoretinal pathology. The aim of this study was to explore the relationship between ADH1 and drug resistance in C. A rotation device carrying MH or SJM valves was implanted in 4 pigs. Macrophage depletion and iNOS antagonism represent 2 promising approaches for preventing aortic aneurysms related to SMAD3 mutations and merit further investigation as adjunctive strategies for the life-threatening manifestations of AOS. Recirculatory models are capable of accurately describing first-pass pharmacokinetics and the influence of cardiac output (CO), which is important for drugs with a fast onset of effect. Delayed myocardial protection to infarction mediated by alpha1-adrenoceptor activation involves an increased bclx/bax ratio, thereby limiting apoptotic cell death. The NGF messenger RNA (mRNA) was measured at various times after incision by polymerase chain reaction. These result in increased plaque accumulation, and particularly in increased interdental effective plaque thickness.

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The influence of age on the susceptibility of sheep to infestation with Schistosoma mattheei. We found 1) LCC values following capture were lower in solitary bears than in bears in family groups suggesting capture caused relatively more stress in solitary bears, 2) ability to cope with handling stress was better (greater LCC values) in bears with good body condition, and 3) LCC values did not appear to be influenced by surgery. The BEACH program, a continuous national study of general practice activity in Australia, gives us an overview of encounters at which chronic musculoskeletal problems were managed. p73, a candidate tumour suppressor gene identified recently in chromosome band 1p36.33, encodes a protein highly homologous to p53. Much of our current understanding of how motors function stems from studies of single motors moving cargos in vitro. Allergic bronchial asthma is one of the most common chronic diseases worldwide. Gallium fluorescence is linear in both the GaCl partial pressure and the laser energy under specified conditions. Especially with smaller volume, military, and third-party uses, documenting a use and/or differentiating between a commercial use and an experimental test batch is not possible.

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Forty-nine subjects aged 55 to 88 years participated in the trial, who received either a TM or NTM on at least 2 occasions during the course of care, and were extracted from the clozaril psych medication larger data set. In this study, HAdV-5 adenovirus death protein (ADP) gene was used to replace the open reading frames (ORFs) of the HAdV-41 E3 region to construct a backbone plasmid pAdbone41ADP. As the time course of neointimal hyperplasia is unknown, a causal relationship between the development of new blood vessels and clinical restenosis cannot be firmly established. Preparation of a novel sorptive stir bar based on vinylpyrrolidone-ethylene glycol dimethacrylate monolithic polymer for the simultaneous extraction of diazepam and nordazepam from human plasma. Patients treated with AZ and SCMC had superior improvements in their nasal symptom GIRs compared to controls overall across the 8 week trial, but not in their ear symptom GIRs. Larger aneurysms and younger age were significantly associated with recoiling. These data suggest that LPS exposure attenuates EDHF-mediated both relaxation and hyperpolarization in the rat mesenteric artery. Nursing care of the CAPD patient with complication of peritonitis.

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Incidental detection of an invasive thymoma during thallium-201 imaging for coronary artery disease. Relative values of the interventions of diversion and improved donor-arm disinfection to reduce the bacterial risk from blood transfusion. Intracellular recordings demonstrated that tetanic stimulation at an intensity equal to that used for synaptic sampling produced, on average, a slight long-term depression of excitatory postsynaptic potentials. Nine hundred eighty-five infants, stratified by site and weight (less than or equal to 2000 g or 2001 to 2500 g), were randomly assigned to receive an educational curriculum focused on child development, as well as family support and pediatric follow-up, or only pediatric follow-up. Whether preoperative knowledge of the BRAF mutation status would help to determine the extent of surgery for thyroid nodules is still under investigation.

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Gender influenced body temperature: the naturally cycling women and the women taking hormonal contraceptives attained their nocturnal minimum body temperatures earlier than the men, and the naturally cycling women had blunted nocturnal casodex class of drug body temperature drops compared with the men. Study of visual evoked potentials during normal monthly cycle in normal female subjects. We report here that in HeLa cells, the abundance of the CDC2Hs mRNA and the rate of synthesis of the encoded protein, p34, vary in a cell cycle-dependent manner. FGF-2 mRNA expression was detected by real-time reverse transcriptase polymerase chain reaction. With the development of newer forms of technology such as low-dose spiral computed tomography, there has been a resurgent interest in screening for lung cancer. Thermoresponsive polymer surface coatings are a promising tool for cell culture applications. Effect of plasma proteins on the specificity of steroid immunoassay. We critically examined the gene frequency data for 11 genetic markers commonly available in the literature for 22 populations of northeastern India in the light of their geographic, linguistic, and ethnic affiliations. The virtual averaging method successfully improved nontracking nonframe-averaged OCT image quality and made the images comparable to active eye-tracking frame-averaged OCT images. Whereas essentially all migration to fMLP across T84 monolayers was prevented by anti-CD18 antibody, significant migration to C5a, IL-8 or LTB(4) persisted despite anti-CD18 antibody, indicating PMN are capable of beta(2) integrin-independent transepithelial migration.

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Low concentrations of thermostable direct hemolysin from Vibrio parahaemolyticus stopped the spontaneous beating of cultured mouse and rat myocardial cells. Topiramate and acute myopia with angle-closure glaucoma: case report and literature review. Radiographically visible vascular plaques should alert the surgeon to potential vascular complications of traction and center-post compression. This study used the well-established Delphi survey, which involves adalat 30 mg asking experts a recurring progression of questions through a series of questionnaires. Hydroxyurea-induced fever in cervical carcinoma: case report and review of the literature. The results highlight both national and regional issues in the provision of health-care services for patients with SCD. The Regulation establishes a European paediatric clinical trials network and a paediatric study programme for off-patent medicines, the latter to be funded through the Community Framework Programmes. Young people often report a protracted journey to diagnosis and frequently report perceived delays. The VAs with greater widths may reasonably be considered enlarged.

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