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Armotraz (Anastrozole)

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Armotraz is used to treat breast cancer in women who have gone through menopause. Some types of breast cancer depend on estrogen to grow, and this medicine can stop tumor growth by blocking estrogen production.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

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Avapro, Celexa, Terramycin, Adipex, Ovral, Mitrip, Etsaid, Azyter, Amantadine, Azitrolit, Plavix,

Also known as: Anastrozole


You should take Armotraz according to your doctor’s or healthcare provider’s instructions.

When to take

You can take your Armotraz dose at any time of the day. But try to stick with the same time each day.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Taking Armotraz with food

You can take Armotraz either with or without food.

Can Armotraz be crushed, split, or chewed?

No, you shouldn’t crush, split, or chew Armotraz tablets. Instead, you should swallow them whole. If you have trouble swallowing pills, talk with your doctor or pharmacist.


The following information describes Armotraz dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Armotraz comes as 1-mg tablets that are taken by mouth.

Dosage for breast cancer

The usual dosage of Armotraz for breast cancer is one tablet taken once a day. It’s best to take your dose at the same time each day.

What if I miss a dose?

If you forget to take a dose of Armotraz, take the missed dose as soon as you remember. However, if it’s almost time for your next dose, just skip the missed dose and take your next dose as usual. Don’t take two doses together to make up for a missed dose.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Will I need to use this drug long term?

Armotraz is meant to be used as a long-term treatment for breast cancer. If you and your doctor determine that Armotraz is safe and effective for you, you’ll likely take it long term.

The length of time that you’ll take this drug depends on the type of cancer you’re using it to treat. Below we describe the typical length of time that Armotraz is given. But to know for sure how long you should take Armotraz, talk with your doctor.

For advanced breast cancer

If you’re taking Armotraz to treat advanced breast cancer, you’ll usually take the drug for as long as your doctor feels this treatment is right for you. (With advanced breast cancer, the cancer has either spread to nearby areas or lymph nodes, called locally advanced breast cancer, or spread to other parts of your body, called metastatic breast cancer.)

For early breast cancer

If you’re taking Armotraz as adjuvant treatment of early breast cancer, you’ll usually take the drug for at least 5 years. Adjuvant treatment is used to lower the risk of your breast cancer coming back or spreading after it’s already been treated with surgery. (With early breast cancer, the cancer hasn’t spread out of either your breast or the lymph nodes in your armpit.)

It’s not currently known if Armotraz should be continued after these 5 years. And if so, it’s not known for how long after the first 5 years it should be taken.

Some studies found that breast cancer is less likely to come back if an aromatase inhibitor is taken for an additional 5 years after the first 5 years of adjuvant therapy. (Aromatase inhibitors are a class of medications.) With this approach to treatment, the drug would be taken for a total of 10 years. However, other studies didn’t show a benefit for extending the treatment beyond 5 the usual years.

In addition, one recent study found that taking Armotraz for a total of 10 years didn’t provide any more benefit than taking it for a total of 7 years.

How long you take Armotraz for early breast cancer will depend on how likely your breast cancer is to come back. It will also depend on your risk of side effects from treatment.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Armotraz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Armotraz can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Armotraz and other medications

Below are lists of medications that can interact with Armotraz. These lists do not contain all the drugs that may interact with Armotraz.

Before taking Armotraz, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Armotraz and tamoxifen

Like Armotraz, tamoxifen is a hormone therapy that’s used to treat breast cancer. But taking tamoxifen with Armotraz can lower the amount of Armotraz in your body. This can make Armotraz less effective for you.

Because of this interaction, you shouldn’t take tamoxifen with Armotraz. However, if recommended by your doctor, it’s fine to take Armotraz after you’ve finished taking tamoxifen.

Armotraz and drugs that contain estrogen

Taking Armotraz with drugs that contain estrogen could make Armotraz less effective for you. Because of this, you shouldn’t take these types of drugs while you’re using Armotraz.

Examples of drugs that contain estrogen include:

  • hormone replacement therapy (HRT)
  • vaginal estrogen products, such as creams and tablets
  • birth control medications, such as pills, patches, and vaginal rings
If you have questions about using medications that contain estrogen with Armotraz, talk with your doctor.

Armotraz and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Armotraz. However, you should still check with your doctor or pharmacist before using any of these products while taking Armotraz.

For example, it’s possible that supplements such as red clover or wild yam could make Armotraz less effective. (These supplements are used by some women to reduce menopausal symptoms, such as hot flashes.)

This interaction is possible because these supplements contain phytoestrogens, which are weak estrogen-like substances found in certain plants. There isn’t enough information available to say for sure whether taking phytoestrogens can affect your breast cancer treatment or not.

Be sure to talk with your doctor before taking any herbs or supplements with Armotraz.

Armotraz and foods

There aren’t any foods that are known to interact with Armotraz. Talk with your doctor to find out if there are any foods you should avoid during Armotraz treatment.

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