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Askapan (Pantoprazole)

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Askapan is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as heartburn, acid reflux, peptic ulcer disease, and some other stomach conditions associated with excessive acid production.

Other names for this medication:
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Also known as: Pantoprazole


Askapan (pantoprazole) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Askapan is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pantoprazole is usually given for up to 8 weeks at a time while your esophagus heals.

Askapan is also used to treat Zollinger-Ellison syndrome and other conditions involving excess stomach acid.


This section provides information on the proper use of a number of products that contain pantoprazole. It may not be specific to Askapan IV. Please read with care.

A nurse or other trained health professional will give you this medicine in a medical facility. It is given through a needle placed into one of your veins.

It may take several days before this medicine begins to relieve stomach pain. To help relieve this pain, antacids may be taken with pantoprazole, unless your doctor tells you otherwise.

Tell your doctor if you have had problems with your zinc levels in your body. Your doctor may want you to take zinc supplements.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Askapan IV dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Askapan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

You should not use this medicine if:

you also take medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey); if you had breathing problems, kidney problems, or a severe allergic reaction after taking pantoprazole in the past; you are allergic to pantoprazole or similar medicines (lansoprazole, omeprazole, Nexium, Prevacid, Prilosec, and others).

Tell your doctor if you have ever had:

low levels of magnesium in your blood; lupus; or osteoporosis or low bone mineral density.

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

Tell your doctor if you are pregnant or breastfeeding.

Pantoprazole is not approved for use by anyone younger than 5 years old.

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Experimental inoculation of Terminalia catappa seedlings with an environmental isolate of Cryptococcus neoformans var. The original SiCOH surfaces are hydrophobic, an indication that they are alkyl- rather than silanol-terminated and that, consequently, they are fairly unreactive. Initial pH as a determining factor of glucose consumption and lactic and acetic acid production in oral streptococci. Surface level expression of both dimeric and monomeric Cx30 were also found to be significantly up-regulated in both hippocampus and cerebral cortex of PAE animals compared to age-matched controls. Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica. Spinal analgesic activity of orphanin FQ/nociceptin and its fragments. After the separation of sister chromatids in anaphase, it is essential that the cell position a cleavage furrow so that it partitions the chromatids into two daughter cells of roughly equal size. Mathematical model of an arterial stenosis, allowing for tethering. Evaluation of oral mucoadhesive microspheres in man on the basis of the pharmacokinetics of furosemide and riboflavin, compounds with limited gastrointestinal absorption sites. NMDA receptor pharmacology and analysis of patch-clamp recordings.

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One of the hallmarks of apoptosis is the digestion of genomic DNA by an endonuclease, generating a ladder of small fragments of double-stranded DNA. We conclude that neurogenic inflammation caused by tachykinin release may be responsible for ozone-induced bronchial hyperresponsiveness, and that tachykinins may play a role in the initiation of airway inflammation. In addition, US application requires no preparation or sedation, making it particularly attractive in the pediatric population. Increased emphasis by funding agencies, fueled in turn by broadening public interest in the topic, led to this growth. The isolated allergen are used for the specific diagnostics of mold mycosis and mycogenic allergy. The presence of a significant number of putative nociceptive fibers supports a possible role for these structures as a source of low back pain and radicular pain.

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Colloid cysts are rare entities in childhood and are not usually included in the differential diagnosis of pediatric sudden death. They have an important immunoregulatory and effector role in IgE-associated allergic disorders, as well as in certain innate and adaptive immune responses. After the second operation the patient developed a slight hearing impairment 3 days postoperatively which increased over a period of two weeks and ended up with total deafness. Antihyperlipidemic activity of adenosine triphosphate in rabbits fed a high-fat diet and hyperlipidemic patients. The technique of sample preparation and gas chromatography are emphasized. Patients with a nonvisualized gland or patients with images suggesting dyshormonogenesis are reevaluated at age 3-4 y to exclude transient PCH. Micro-TA makes it possible to characterize separate phases of itraconazole and Eudragit E100, thereby confirming the MTDSC results on phase separation. Temperatures as low as 225-233 degrees K permit activity in some media. The first small-molecule inhibitor of 14-3-3s: modulating the master regulator. We postulate that upon entering the cytoplasm, AcMNPV nucleocapsids induce the polymerization of actin cables, which, in conjunction with a myosin-like motor, facilitate their transport to and/or into the nucleus.

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Mohs fixed-tissue excision of dentoalveolar bone in canines: a histologic evaluation. The resolution of the process is sufficient to fabricate pixelated matrix displays. There was no significant difference in the systemic response between perforated and non-perforated groups. Single oral administration of 12-36 mg of anthocyanosides appears to lack significant effect on militarily relevant night vision tests. Differential gene expression for interleukin-13 and other cytokines in the skin of atopic dermatitis patients and healthy subjects. A thorough knowledge of head and neck tuberculosis is important because early diagnosis and therapy may prevent a permanent loss of function or needless surgery. The objective of this study was to explore the feasibility of utilizing n-butyl-2 cyanoacrylate, a polymeric adhesive, for fixation of the zygoma after fracture displacement.

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Both FeCl2 and H2O2 reduced GS activity whereas NMDA produced a large increase in enzyme activity. Assessment of red cell autoantibodies in autoimmune hemolytic anemia of warm type by a radioactive anti-IgG test. Qualitative research could examine specific experiences and contexts of vulnerable women. A plasmid overexpression strategy was used to isolate a new gene, AFR1, which acts together with the receptor C terminus to promote adaptation. Increasing diluent volume led to significantly greater delivery of the albuterol initially placed in the nebulizer.

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Expression of vascular endothelial growth factor in experimental choroidal neovascularization. This sample was selected at random from a set of 350 strains isolated from tuberculosis patients from central and eastern areas of the country. Understanding apoptosis from these perspectives sheds substantial light on processes of biological homeostasis. Neuronal survival did not change with time in culture when cells were treated with C2-ceramide or staurosporine, agents which do not target DNA. The study is a culturally adapted lifestyle intervention aiming at reducing diabetes risk among Pakistani women, Oslo, Norway. Closure of the mesenteric defect was associated with a higher rate of complications, and demonstrated no benefit in abdominal colectomy. Here, we determine the entire microRNAome of three endoderm-derived tissues, liver, jejunum and pancreas, using ultra-high throughput sequencing.

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The broad-host-range plasmid pLA2917 was transferred into Hyphomicrobium species by a triparental mating. It starts with a conversation: a community approach to creating healthy work environments. This paper aims to review and update basic theoretical notions of tooth mobility after evaluation of recent studies. All patients admitted to one psychiatric hospital were followed from date of first admission after 31 July 1980 until 31 December 1992 with regard to death, by linkage to the Norwegian Central Register of Persons. To efficiently translate experimental methods from bench to bedside, it is imperative that laboratory models of cancer mimic human disease as closely as possible. We conclude from these studies that the miRNA biogenesis components Drosha, Dgcr8, Exportin-5 and Dicer1 are expressed in the mouse uterus and that Exportin-5 and Dicer1 appear to be the major steroid regulated components in the miRNA biogenesis pathway. The vaginal flora contains a large variety of bacterial species, including both aerobic and anaerobic organisms. Thus, we suggest that, in addition to being an anti-microbial peptide, LL-37 also plays a part in wound closure and that its reduction in chronic wounds impairs re-epithelialization and may contribute to their failure to heal. Microelectrode recordings were carried out in both groups prior to and during subthalamic nucleus stimulation. With regard to the inverted U-shaped relation between the dose of the drug and the number of self-infusions, it seems that activation of the kappa-opioid receptor with U50,488H produced an almost parallel shift to the left, indicating an increased sensitivity of the animals for the reinforcing effects of cocaine and morphine.

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Neurotrophin receptor mRNA and protein expression were quantified. Numerous cartilage grafts from a number of donor sites have been described, each with a different shape and size. Methionine 4 is the most reactive group, followed by methionines 72 and 178--methionine 123 being the less reactive residue. The purified protein has a molecular mass of about 35 kDa and exhibits binding affinity toward both 5S rRNA and 5S rRNA gene. The only noticeable finding leading to the diagnosis was the pathological result of the routine cervical smear. Early coagulopathy and metabolic acidosis predict transfusion of packed red blood cells in pediatric trauma patients. To assess the potential of physical training to restore better physical capacity after percutaneous transvenous mitral commissurotomy, 26 patients with mitral stenosis were studied after the procedure. The results show that the conversation partners in this case cooperate in making the conversation proceed and evolve, and that verbal repetition is used in a way that works as a strategy for compensating for the what type of medication is plavix impairment. New shuttle vectors for the introduction of cloned DNA in Desulfovibrio.

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Auditory cortex primary response to acoustic signals of various steepness of front increase. AtRZ-1b and AtRZ-1c proteins, being localized to the nucleus, have been shown to bind non-specifically to RNA sequences in vitro, in comparison to AtRZ-1a that is localized to both the nucleus and the cytoplasm and binds preferentially to G- or U-rich RNA sequences. A case of a 31-year-old female with congenital esophageal stenosis presenting with symptoms of chest pain caused by esophageal dysmotility is described. This tumor is equivalent to the polymorphous low-grade adenocarcinoma of minor salivary glands. This study aimed to identify key capsid regions which can be engineered to overcome these limitations. Our results suggest that having a sobriety checkpoint law and conducting checkpoints as well as enforcement of open containers laws may be effective strategies for addressing drinking-driving. Single doses of 200 mg, 400 mg, or 600 mg mifepristone followed, 48 hours later, by vaginal pessary of 1 mg of the prostaglandin E1 analogue gemeprost. However, in SHR insulin did not reduce blood pressure as in WKY but after about 15 min it significantly enhanced blood pressure and reduced iliac conductance.

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Clinical problem-solving: interpreting hoofbeats: can Bayes help clear the haze?. The reappearance of REM sleep at about 3 hr following melatonin administration occurred with a marked rebound. In NHK, NiSO4 and pPD induced ICAM-1 expression to a significantly greater extent in proliferative cells than in differentiated cells, where involucrin expression was measured to assess the differentiation state. GSSG increases the rate of zinc transfer 3-fold, and its concentration is the major determinant for efficient zinc transfer. The endocellular microbe Wolbachia pipientis infects a wide variety of invertebrate species, in which its presence is closely linked to a form of reproductive failure termed cytoplasmic incompatibility (CI). Accordingly, the authors tested the hypothesis that intraoperative core hypothermia triggers nonshivering thermogenesis in infants. Specifically, the existence of a singularity property is pointed out, at which interaction force estimation is impossible, and close to which it may be infeasible. Here we report that FKHR regulates fusion of differentiating primary myoblasts. To study whether prospective measurements of circulating concentrations of brain natriuretic peptide (BNP) could predict mortality in the general elderly population.

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Preparations enriched in syncytiotrophoblastic plasma membrane microvilli have been isolated and their polypeptide composition analysed by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate. Although CON cows appeared to have a less stressful transition into lactation, SM supplementation was effective in alleviating negative effects of energy-overfeeding. In cultured rat-derived smooth muscle cells, LTB4, an active metabolite of 5-lipoxygenase whose biosynthesis in air pouch exudate was suppressed by MK-886, stimulated cell migration. Sympathetic lesions in experimental avitaminosis-induced alopecia. These precursors are then used to generate the entire biomass of the cell.

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Outpatient management of heart failure (HF) is aimed at treating symptoms and preventing hospitalizations and readmissions. Ultimately, definitive diagnosis with sputum, bronchoscopy with bronchoalveolar lavage, or lung tissue is often needed. We enrolled 126 patients with urological dysfunction who were recruited between July 2008 and January 2015 in Beijing Tian Tan Hospital, Capital Medical University and conducted overactive bladder system score (OABSS), urodynamic investigation, and expanded disability status scale (EDSS). Congenital bilateral anophthalmia associated with a severe risperdal medication reviews psychomotor deficit. Commentary On: Self-Care Self-Efficacy, Religious Participation and Depression as Predictors of Post-Stroke Self-Care Among Underserved Ethnic Minorities. Identifying young adult substance abusers: the Rutgers Collegiate Substance Abuse Screening Test. Early cellular and humoral response after vascular prosthesis implantation in the arterial system. Physical activity and health-related quality of life in young adult cancer survivors: a Canadian provincial survey. These results suggest that enhanced neutrophil chemotactic activity distinct from IL-8 may contribute to significant bronchoconstriction induced by grain dust. Formation of a ternary NFAT.C/EBP.DNA complex is required for the transcriptional cooperation.

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