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Atacor (Atorvastatin)
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Atacor

Atacor is a lipid-lowering drug included in the statin class of medications. It ultimately reduces the risk of cardiovascular disease. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase, which catalyzes the conversion of HMG-CoA to mevalonic acid.

Other names for this medication:
Alvastin, Ampliar, Anzitor, Atacor, Atasin, Atenfar, Ateroclar, Atorin, Atoris, Atorvin, Atorvox, Atovin, Atroact, Avascare, Biger, Danelip, Divator, Lipivastin, Lipizem, Lipizim, Lipofin, Liporest, Lipostop, Prevencor, Tarden, Tarimyl, Taven, Trova, Voredanin

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Also known as: Atorvastatin

Description

Atacor (atorvastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins."

Atacor is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Atacor is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors such as genetically high cholesterol.

Atacor is for use in adults and children who are at least 10 years old.

Dosage

Take Atacor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Atacor is usually taken once a day, with or without food. Take the medicine at the same time each day.

Do not break an Atacor tablet before taking it, unless your doctor has told you to.

You may need to stop using this medicine for a short time if you have:

uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood); severely low blood pressure; a severe infection or illness; or surgery or a medical emergency.

It may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. Even if you have no symptoms, tests can help your doctor determine if Atacor is effective.

Atacor is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Atacor dosage information

Overdose

If you overdose Generic Atacor and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Atacor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid eating foods that are high in fat or cholesterol. Atacor will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

Grapefruit and grapefruit juice may interact with atorvastatin and lead to unwanted side effects. Avoid drinking more than 1 liter of grapefruit juice per day while taking this medicine.

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Image-guided implantation of pre-calibrated catheters in the ICU: a feasibility study. The individual number of pathological scores showed a decrease already within the first treatment week and a further decrease by the end of the trial, especially for the items of capriciousness, obstinacy, irritability and restlessness. ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells. Numerical results show that, irrespective of the pacemaker introduced to one single neuron or all neurons of the network, the phenomenon of stochastic resonance occurs. However, there are abnormalities in the immune system which may be implied in the pathogenesis.

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International efforts should be devoted to developing a minimum standard data set for trauma patients. Novel phenotypes related to the breeding of purple-fruited tomatoes and effect of peel extracts on human cancer cell proliferation. The PASSIST was designed to be simple, fully autoclavable, slender, and stiff. Further, late peaks were observed in the parietal, sensory-motor and left temporal regions. We evaluate the approach with a simulated example of thorax imaging, and also with experimental data from a laboratory setting, with absolute imaging considered in both cases.

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Detection of this species strongly argues for obligate coupling of histone deacetylation to NAD breakdown by Sir2. Participants with T2DM, with T1DM, and without any indication or known family history of diabetes were fingerprinted with a Crossmatch Verifier 320 LC scanner. The population of the initial streptomycin-sensitive culture was characterized by high homogeneity with respect to the cultural, morphological and some physiological properties. They should also be encouraged to have proper therapy so that they may be returned to a more normal ocular status at the earliest possible age. Bacteria such as Escherichia coli and Salmonella typhimurium swim by rotating their flagella, each of which consists of an external helical filament and a rotary motor embedded in the cell surface. We present a framework for optical tomography based on a path integral. Single and double immunoelectron microscopic labeling showed vimentin filaments in all these neoplastic myoepithelial cells. To evaluate the sensitivity of microorganisms to bactericidal activity of phagocytes, monocytes and granulocytes separated from peripheral blood by standard density gradient and by counter-current centrifugal evaluation these cells were incubated with suspensions of opsonized bacteria. Radiofrequency transmission to monitoring devices in the operating room: a simulation study.

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Matrix metalloproteinase-9 in myeloid cells: implications for allergic inflammation. When used appropriately, QUS devices can play an important role in the assessment of osteoporosis. We found that a significant shift in the abundance and relative distribution of bacterial species in the ileum of mice is associated with H. Seasonal variations of lipid content and composition in Perna viridis. Reference values of diffusing capacity of non-smoking Chinese in Hong Kong. Due consideration should be given to these potential barriers to address the underrepresentation of BME groups in physiotherapy. To estimate the proportion of group B streptococci (GBS)-colonized women with a reported penicillin allergy without anaphylaxis receiving appropriate intrapartum antibiotic prophylaxis. These data together with others reported in the literature show the possible clinical applications of this technique. A large set of arguments advocates that reverse-transport plays a role in the maintenance of basal extracellular DA concentration in striatum. The novel duplex RT-PCR described in this study enables the early diagnosis of these two encephalitic flaviviruses.

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The small Maf proteins, MafF, MafG, and MafK, possess a leucine zipper (Zip) domain that is required for homodimer or heterodimer complex formation with other bZip transcription factors. We found that under the proteolytic conditions where the enzyme was present in nanomolar concentration or higher, in excess over the substrate, the proteolysis of substrate phage was a single exponential event and the observed rate linear with respect to enzyme concentration. Ratings on Likert scales about perceived healthfulness, helpfulness for weight management, and caloric content. At the high cadmium concentrations, significant changes occurred in plant length and in the amounts of dry weight, chlorophyll, total soluble phenolics, and free proline. There is much interest in defining the nutrient dependencies of cancer cells and their mechanisms of adaptation to nutrient depletion. Samples were collected in the intensive care units of a 600-bed university hospital over a period of 2 months. Monocytes, present in every phase of atherogenesis, are the principal cells accumulating in atherosclerotic plaque.

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Inhibitory effects of grape procyanidins on free radical-induced cell damage in rat hepatocytes in vitro. Inheritance and meiotic behaviour of a de novo chromosome fusion in the aphid Myzus persicae (Sulzer). Here, we used targeted mutagenesis to examine a potential role of S. In this study, to compare the MPA-inducible osteopenia with the ovariectomy (OVX)-inducible one, female rats were used instead of male rats and a time-course study of development was made. Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity. Lesions produced by splinters of wood in the soft tissues and bones of the limbs are not uncommon and may be difficult to diagnose. Experience overseas suggests that radiographer reporting can reduce patient waiting times, release radiologists for other duties and improve the retention of radiographers. Adrenal changes in response to an acute stress-effect (5 h-immobilization stress) were investigated in female rats exposed to hypokinesia for 3 months. This retrospective series provides preliminary data on effective dose and appropriate time of intervention to aid in the design of a prospective trial to further define the role of ketamine in the treatment of RSE.

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Drug therapy in cats: mechanisms and avoidance of adverse drug reactions. Spines present in soft tissue sections contained no calcium but did contain chitin as shown by a von Wisseling reaction for chitosan. Variation of pKa in the N-terminal tyrosine side chain in octapeptide analogs of tendamistat influences alpha-amylase inhibition. In the second method, random domain-localized (RDL) mutagenesis, a mutation is introduced at random within a specific domain of a gene. Most of methane in flooded rice fields is emitted via transport through the plant gas vascular system. Antiemetic procedure is now an indispensable supportive care for cisplatin-based combination chemotherapy. While only minor changes in anodic DPV response of guanine and adenine could be seen after 60 min exposition to UV-B and visible light, total degradation of DNA bases was observed after 20 min exposure to UV-C.

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Functionally acceptable substitutions in two alpha-helical regions of lambda repressor. Ultrasound screening for fetal urinary tract malformations: a prospective study in general population. The absence of bone remodelling shows that the sutures, at the time of sampling, were in a resting stage. It is important to identify the possible risk factors for the occurrence of large for gestational age (LGA) in newborns and to determine the effect of birth weight and metabolic parameters on subsequent growth. Transplantation of the bear microbiota from summer and winter to germ-free mice transferred some of the seasonal metabolic features and demonstrated that the summer microbiota promoted adiposity without impairing glucose tolerance, suggesting that seasonal variation in the microbiota may contribute to host energy metabolism in the hibernating brown bear. Here evidence is provided that glomerular damage in this murine model is due to overproduction of oxygen radicals and accumulation of lipid peroxidation adducts that were found in isolated glomeruli of Mpv17-/- mice. Longitudinal contraction venoplasty may be an effective new method for prevention of internal jugular vein thrombosis after free flap vascular anastomosis.

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Understanding the mechanism of its formation has enabled isotope (D) labeling. Where there were fewer than 100 prescriptions in a month, all the prescriptions available were sampled for analysis. This evidences a decreased function of the epiphysis in these groups of tumor patients. Sodium taste detectability in rats is independent of anion size: the psychophysical characteristics of the transcellular sodium taste transduction pathway. Rigorous assessment of the value of predictors is crucial before implementation. Data from collaborative trials clearly indicate that the primary effect of adjuvant therapy is to delay death from breast cancer by months or years. Nutrient sensing molecules are central to cell growth and metabolism and are implicated flagyl contraindications with alcohol in cancer and the metabolic syndrome. Preclinical safety evaluation of avasimibe in beagle dogs: an ACAT inhibitor with minimal adrenal effects. The parental strains differed by the adrenal weight, plasma corticosterone level and in vitro adrenal secretion rate. In contrast, sensitivity to direction of motion and to differences in surface texture may be greater on skin sites located on the lower face.

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Optimization of nonlinear optical localization using electromagnetic surface fields (NOLES) imaging. Cytokine and endotoxin concentrations increased significantly in all groups. The objective was to investigate the effect of individual fatty acid intakes on postprandial plasma lipoprotein triacylglycerol and cholesterol concentrations, plasma fatty acids, and preheparin lipoprotein lipase and cholesterol ester transfer protein (CETP) activities. Molecular structures of some vertebrate-type messenger peptides in invertebrates. Enteric stem cells have been proposed as an appropriate cell source to provide an alternative therapeutic option for a number of neurogastrointestinal diseases, however a better understanding of these cells would be crucial for the translation of cell-based therapies into clinic.

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Here screening and trapping were combined in one tool to control mosquito populations. Findings indicated that SES, age, race/ethnicity, gender and marital status independently predicted changes in mental health ratings at wave 2. Paraquat induces cyclooxygenase-2 (COX-2) implicated toxicity in human neuroblastoma SH-SY5Y cells. Recent achievements in organ bioengineering and regeneration have provided proof of principle that the application of organ bioengineering and regeneration technologies to manufacture organs for transplant purposes may offer the quickest route to clinical application. In a longitudinal experimental study, 8 representative Kansas City communities were assigned randomly to program (school, parent, mass media, and community organization) and control (mass media and community organization only) conditions. giganteus differ from the small Lower Muschelkalk (Nothosaurus marchicus/N. We assessed whether the pleiotropic effects of statins can reduce delirium in intensive care and decrease subsequent cognitive impairment in a randomised controlled trial. Halothane anesthesia reversibly inhibited metabolic rhodopsin regeneration and thus prevented rhodopsin from absorbing high numbers of photons during light exposure. The long-term antimicrobial efficacy of silver dressings against bacterial biofilms was investigated in a 7-day treatment in vitro model where the protein-rich medium was refreshed daily in order to mimic the conditions found in a wound bed. Role of glutathione in the regulation of hepatic cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme of bile acid biosynthesis.

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