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Avodart

Avodart can be taken any time of the day but it works best when taken at the same time each day. If you are also taking other medications for your prostate like Flomax (tamsulosin), it might be a good idea to take these together.

Other names for this medication:
Alfuprost, Alfusin, Duagen, Duprost, Durize, Dutalfa, Dutas, Dutasteride, Dutride, Flodart, Jalyn, Jyotam, Sterdu, Tamcontin, Tamdura, Urifine, Urimax, Uritin, Veltam, Veltride

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Also known as: Dutasteride

Description

Avodart is produced by GlaxoSmithKline. Benign prostatic hyperplasia (benign prostatic hypertrophy or benign prostatic adenoma) is an overgrowth of cells of the prostate due to the aging process and hormonal changes. The enlarged prostate squeezes the urethra, obstructs the urine flow and makes it difficult for the patient to void his bladder. BPH is characterized by frequent urination, urgency to urinate (compelling need to void that cannot be deferred), involuntary urination, urge incontinence, urinary hesitancy (a delay between trying to urinate and the flow actually beginning), intermittency (not continuous), involuntary interruption of voiding, weak urinary stream etc. Avodart soft gelatin capsules (softgels) contain the active ingredient Dutasteride which aim is to inhibit the action of both isoforms (type I and type II) of the enzyme 5α-reductase, that converts the male sex hormone testosterone to dihydrotestosterone (DHT). DHT is another male sex hormone (androgen) that causes the growth of prostate gland. This helps to relieve such symptoms of BPH as starting to urinate, weak stream, and the need to urinate frequently or urgently (including during the middle of the night). Taking Avodart may also reduce the need for surgery to treat BPH. Avodart can be used for the treatment of male pattern baldness (MPB) or androgenetic alopecia (AGA) off-label. DHT, which is also found in hair follicles, is the androgen responsible for hair loss, as it causes hair follicles to miniaturize and atrophy. Avodart softgels reverse hair loss process as it blocks the build-up of DHT in the hair follicles of the scalp, allowing the hair to grow normally.

Dosage

For the treatment of BPH: Take one softgel orally (by mouth) once a day, with or without food. You should take the Avodart softgels at the same time every day. Take Avodart daily for at least 6 months or more if necessary before any noticeable results occur. If Avodart has not worked for you over a 12 months course then it is unlikely that further treatment will benefit. Do not stop taking Avodart suddenly, as any therapeutic benefits will be reversed. Always consult your doctor or pharmacist if you want to stop the treatment before time or if you are intended to prolong treatment. For the treatment of MPHL (off-label): Take one softgel orally (by mouth) once a day, with or without food. You should take the Avodart softgels at the same time every day. Take Avodart softgels daily for at least 3 months or more if necessary before any noticeable results occur. If Dutasteride has not worked for you over a 12 months course then it is unlikely that further treatment will benefit. Do not stop taking Avodart capsules suddenly, as any therapeutic benefits will be reversed. Always consult your Avodart or pharmacist if you want to stop the treatment before time or if you are intended to prolong treatment.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Avodart are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Avodart if you are allergic to Generic Avodart components. Be careful using Generic Avodart if you take ritonavir, nefazodone, diltiazem, verapamil, ketoconazole taken by mouth, itraconazole, indinavir. It can be dangerous to use Generic Avodart if you suffer from or have a history of severe decreasing liver function, urinary tract disease, mild to moderate decreasing liver function, prostate cancer, liver disease. If a woman of a man who is taking Generic Avodart is a pregnant or plans to be pregnant he should use a condom while sex. Generic Avodart can pass into semen and harm the baby. Avoid alcohol. Do not stop taking Generic Avodart suddenly.

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