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Calmef (Alprazolam)

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Calmef is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Albiz, Aleez, Alpkair, Alprac, Alpraday, Alprocalm, Alproz, Alwe, Alzin, Ambutech, Andep, Anzal, Axizox, Betapax, Depflu, Depten, Dizeral, Erazol, Esteem, Fultop, Hipose, Mediprex, Meloprax, Nitril, Normatine, Oclam, Pizolam, Poize, Prazolam, Propnix, Prozolam, Riolam, Samprex, Sertamax, Setex, Somnia, Tenan, Tensyn, Tranax, Trapose, Trazopin, Trika, Tryzo, Unixl, Viprax, Xanti, Zoldac, Zomark, Zopain

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Calmef XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Calmef XR may be habit-forming and should be used only by the person it was prescribed for. Calmef XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Calmef extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Calmef XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Calmef XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Calmef XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Calmef XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Calmef XR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Calmef are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Calmef from your body, which may affect how Calmef works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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Many of premalignant cervical lesions will never progress to invasive malignancy, or even may regress over the time. This case describes a rare late complication secondary to surgical treatment of an acetabular fracture. Infrared spectroscopy and magnesium content of bone mineral in osteoporotic women. Whether COX-2 inhibitor therapy would be beneficial in the prevention and/or treatment of ovarian cancer, the most lethal gynecological malignancy worldwide, is not known. However, there is growing experience with the off-label use of PCCs to treat patients with surgical coagulopathic bleeding. Reversible folding of the polypeptide domain of GroEL guarantees highly efficient chaperonin activity within the GroEL toroid. The regional cerebral perfusion rate of the grey matter was compared with angiographic data. Longitudinal data were also collected for 279 of the subjects after a mean of 139 days. Wistar male rats, 3 months of age were given ad-libitum a nutritionally adequate diet and demineralized drinking water. The WHO/UNICEF international code of marketing of breast milk substitutes: principal provisions.

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Tranquilization and sedation by the use of a combination of small doses of reserpine and pentobarbital sodium. Allantoin transport protein, PucI, from Bacillus subtilis: evolutionary relationships, amplified expression, activity and specificity. Part two addresses how to apply an appropriate valuation methodology to determine worth. An unusual case is presented in which a fragment of herniated lumbar disc was found within the sheath of the right S-1 nerve root. Effects of SR140333, a selective non-peptide NK1 receptor antagonist, on trigemino-thalamic nociceptive pathways in the rat. temperata, and the relationships among these subgroups were confirmed by gyrase subunit B (gyrB) gene sequence analysis. FATTY MUSCLE INFILTRATION IN CUFF TEAR: PRE AND POST OPERATIVE EVALUATION BY MRI. If hospitals are to succeed in their efforts in cost control, they must segregate the influence of efficiency and effectiveness and integrate the medical staff into the management structure. Nitrogen sparing action of neutral fat and fatty acids in the phlorhizinized rat.

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A novel testosterone gel formulation normalizes androgen levels in hypogonadal men, with improvements in body composition and sexual function. Despite this risk, we hypothesize that the good use of these new technologies might be useful to develop new methods of cognitive training. Replacement of failing tunneled hemodialysis catheters through pre-existing subcutaneous tunnels: a comparison of catheter function and infection rates for de novo placements and over-the-wire exchanges. Furthermore, suppression of EVI1 expression decreased the proliferation of HCC cells overexpressing HBx in vitro and in vivo. The conserved serine-tyrosine dipeptide in Leishmania donovani hypoxanthine-guanine phosphoribosyltransferase is essential for catalytic activity. Comparison of observed costs with estimated costs of adherence to the treatment standard. Restricting the expression of this gene to the bundle sheath led to the establishment of a photorespiratory CO2 pump. Pups of both ages reduced rates of ultrasonic vocalization (USV) when an adult was placed into the test cage, independent of whether the adult was their dam or an unrelated male. Nifedipine induces overgrowth of gingival tissues in some patients.

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The 36-year-old patient recently sought medical treatment for a reported ankle sprain, but the pain was recalcitrant to conservative care. Unexpected results of the Childhood Acute Myelogenous Leukemia Study BFM-87. coli associated with UTI in Galicia and consider the most appropriate antibiotics for empirical treatment. Sperm with an abnormal tail (most of them were sperm with a folded tail) increased at the cauda epididymis before the epididymal sperm reduction became apparent. Circulating fibroblast growth factor-23 increases following intermittent parathyroid hormone (1-34) in postmenopausal osteoporosis: association with biomarker of bone formation. Finally, given that other systems than the CNS can be involved in histological or biochemical abnormalities, such as the reproductive system, we must ask what other types of functional pathology can be induced by interventions on gametes, the embryo and the fetus. Articular cartilage calcification of the humeral head is highly prevalent and associated with osteoarthritis in the general population. This longitudinal case study is based on an interpretive approach, whereby data were gathered through 440h of participant observation, 22 semi-structured interviews and extensive document studies over 4 years. Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival.

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GABA(A) receptors in the pontine reticular formation of C57BL/6J mouse modulate neurochemical, electrographic, and behavioral phenotypes of wakefulness. It is also found that introducing tetraethyltin (TESn) doping during nanowire growth severely degrades the Dit profile. In cultured granule cells, the increase in p21cip1 expression induced by BDNF occurred after dividing granule cells had left the cell cycle and thus was not required to direct granule neuron precursors out of the cell cycle. We studied the effects of surgical task complexity on the gaze metrics of surgical trainees. Generation of major histocompatibility complex class I antigens. CPA signals in hepatic hemangiomas appear to be related more to architecture than to true capillary flow. Each detection group contained three to four crop-specific primers designed to the same region of the gene encoding the highly conserved RNA-dependent RNA polymerase gene (RdRp) of criniviruses for rapid, single-reaction determination of which crinivirus(es) may be infecting a plant. This may become particularly critical in a few years when the Congress and HEW are less patient and more insistent that evidence of clear cost control benefits will have to be produced if the nation is to continue to invest in health planning. The case of a pediatric patient with myositis ossificans progressiva in whom it became increasingly difficult to obtain local anesthesia is presented.

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Both acoustic and perceptual analyses suggest that the influence of the Lombard effect on male and female speakers is different. Oxyradical-mediated chromosome damage in patients with familial Mediterranean fever. ACTs are relatively safe and tolerable with no reported resistance in sub-Saharan Africa despite indications of delayed clearance of infections in south-east Asia. In this chapter, we focus on the initial steps of O2 sensing in tissues most commonly studied, i.e. In this work, we present a systematic study of the optimization of leaf sequencing algorithms for segmental multileaf collimator beam delivery and provide rigorous mathematical proofs of optimized leaf sequence settings in terms of monitor unit (MU) efficiency under most common leaf movement constraints that include minimum leaf separation constraint and leaf interdigitation constraint.

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Cutaneous leukocytoclastic vasculitis and renal cancer: two cases. 2 min before killing by perfusion fixation showed substantial leakage. So the aim of the study was to investigate the effects of TCM on stroke risk among patients with vertigo. In Hif1a-/- knockout mice, complete deficiency of HIF-1alpha resulted in cardiac and vascular malformations and embryonic lethality at E10.5. The rat pancreatic development in utero could be divided into four representative stages as follows: (1) initial epithelial buds (12 days of gestation), (2) elongated and branching epithelium (13-14 days), (3) tubular structure (15-16 days), and (4) acinar structure (17 days or more). A longer follow-up may be necessary to confirm the stability of results. This nonresective, recurrence-free procedure provides a cure for nongangrenous sigmoid volvulus.

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These data confirm the association of douching and anal sex with various STD and suggest that sex during menses is associated with chlamydial infection. Public concern surrounding the effects video games have on players has inspired a large body of research, and policy makers in China and South Korea have even mandated systems that limit the amount of time players spend in game. The formation of the biaxial texture in Al film relies on the existence of the CaF(2) buffer layer prepared using oblique angle physical vapor deposition, which consists of single-crystalline nanorods with caps that are in the form of inverted nanopyramids. The role of adjuvant therapy in biliary malignancies needs further evaluation. Inappropriate referrals have extended already lengthy outpatient waiting times in other specialities. Alcohol consumption level in Russia: a viewpoint on monitoring health conditions in the Russian Federation (RLMS). In most cases these receptors share common signal transducing receptor components in the same family, which explains the functional redundancy of haematopoietic cytokines.

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We found out that NT-proBNP is significantly elevated in patients with AF with preserved left ventricular function and in absence of heart failure and significantly correlates with age, left ventricular ejection fraction, left atrial diameter, body mass index and the furosemide dose necessary to achieve cardiac compensation. A Purkinje potential recorded at the junction of the left ventricular mid-septum and inferior wall preceded the ventricular complex by 40 msec in both tachycardias. These findings suggest that activation by OBF-1 is not obtained by simple recruitment of the coactivator to the promoter but requires interaction with DNA-bound Oct-1 to stimulate a step distinct from those regulated by classical activation domains. Two experienced blinded observers reviewed all cases both from films and from the computer screen with contrast adjustment when needed. Instantaneous and causal connectivity in resting state brain networks derived from functional MRI data. These studies were complemented by neurofilament protein immunocytochemistry on the sciatic nerve 20 days after an operation, in which an 8-mm piece of the nerve was removed and replaced by a graft of laminin, its neurite outgrowth-promoting peptide, a control peptide, collagen, or by resuturing of the removed piece of the nerve. The application of testosterone and its analogues for people exceeds, by their effectiveness, the known treatment methods. To examine the extent to which outcomes from traumatic brain clozapine pill image injury differ as a function of time and can be predicted at discharge from inpatient rehabilitation. A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. After surgery, the patient experienced hearing loss and a right internal capsule infarct, in addition to complete vision loss in the left eye.

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When managing hypertension, therapy should be focused on medications with the strongest evidence for CV event reduction, substituting alternatives only when a primary choice is not appropriate. These results demonstrate that the studied species have different strategies for acquisition and use of mineral resources and acclimation to light, which are determinant for them to coexist in the forest environment. However piribedil, which is a dopaminergic receptor agonist, reduced the concentrations of all 3 metabolites considered, while nomifensine produced an increase, and quipazine caused an early rise in 3-MT followed by a lowering of the concentration of dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA). Protein assemblies are zyrtec d generic modeled using a recently introduced coarse-grained modeling framework based on the finite element method, which is used to compute equilibrium thermal fluctuations, elastic strain energy distributions associated with specific conformational transitions, and dynamical correlations in distant molecular domains. To determine whether intrapartum magnesium sulfate (MgSO4) therapy for seizure prophylaxis in pre-eclampsia-eclampsia is associated with biochemical evidence of subacute fetal myocardial damage at delivery. Isolation, purification and characterization of chymosin from riverine buffalo (Bubalos bubalis). Our results strongly suggest differences in cocaine and cannabis consumption between US and German plasmapheresis donors.

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Here, we report the use of DiI-labeled acetylated low-density lipoprotein (DiI-Ac-LDL) to label endothelial cells and characterize the vasculature of live Xenopus embryos. The dispersions emerged as categories that repeat themselves as subjects of note or as smaller punctuation. A tool for the qualitative comparison of membrane-embedded and detergent-solubilized membrane protein structures in projection. Longitudinal findings from a Norwegian case-cohort study on internalizing problems in children with congenital heart defects. The occlusion of the fistula by transcatheter or cardiac surgery is appropriate, especially as the risks of the interventions are limited. SLE-associated HS might be underdiagnosed due to the overlap in clinical findings.

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The diagnosis of posttraumatic BPPV is not different from the idiopathic form, but the treatment may require more maneuvers to achieve satisfactory results. Formation of N-2-fluorenylhydroxylamine adducts of DNA in vivo and in vitro and some of their properties. To examine the long-term effects of space-like proton exposures on immune status, we treated female C57BL/6 mice with 3 or 4 Gy of 250 MeV monoenergetic protons or the complex space-like radiation field produced after 250 MeV protons are transported through 15 g x cm(-2) aluminum shielding. Mechanism of action of Rauwolfia alkaloids and phenothiazine derivatives in schizophrenia. Of the 1,204 men who met the initial eligibility criteria 420 had a negative prostate needle biopsy (noncancer comparison group). Local and systemic immune responses also were detected in monkeys immunized intravaginally with recombinant S. Uptake of 99mTc-pertechnetate in salivary glands reflects intact salivary gland parenchyma. The lobus parolfactorius (LPO) has been implicated in memory formation associated with passive avoidance training of young posthatch domestic chicks. We address three questions: Do comparisons of LE cases with non-LE cases that have suggestive skin lesions yield criteria for use in dermatology clinics for primary classification of cases with photo distributions of skin lesions?. High-affinity ammonium transporters and nitrogen sensing in mycorrhizas.

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Suspended Wi38 lung cells also adhered to the tumor cell aggregates. Both gamma and zeta were observed to induce a phagocytic signal, but gamma was at least sixfold more effective than zeta. Preoperative computed tomography analysis of cochlear anatomy was compared with operative findings, complications, and postoperative cozaar brand name coverage device use. The influence of heat-induced epitope retrieval on endogenous avidin-binding activity (EABA) and blocking of EABA in immunohistochemistry. Fracture healing was similarly enhanced in the groups with cyclic compression and cyclic distraction. Different asparaginase preparations were monitored in children on the ALL-BFM induction and reinduction treatment (10,000 U/m2 every 3-4 days).

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Water purifying system could save lives in developing countries. In this study, we clarify the GA biosynthetic pathway from GGPP to ent-kaurenoic acid and provide a foundation for further characterization of the subsequent enzymes involved in this pathway. All responses were recorded electronically and the data were subsequently analysed. This group is often allocated a donor after cardiac death (DCD) liver as a diflucan dose urinary tract infection solution for waiting times. Administration of rHb1.1 to conscious humans is associated with some side effects, such as gastrointestinal upset, fever, chills, headache, and backache. This greatly simplifies any calculations in which dioptric power matrices are obtained in intermediate steps, including separated obliquely crossed spherocylindrical lens calculations.

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In the later stage of the clinical development of new vaccines it is required to demonstrate their efficacy with the immunogenicity measures established as correlates for disease protection. Five mixed analyses of variance with follow-up tests showed a significant difference for all outcome measures in the treatment group compared with the control group. To study the distribution of clinically important red cell antibodies in pregnancy, and the associated fetal and neonatal morbidity and mortality. Return cycle mapping after entrainment of ventricular tachycardia. Brief note on modern orientations in the health fight against pinta. The authors report a patient who developed a mononucleotic syndrome after 2 months treatment with diphenylhydantoin. The demonstration of a who makes the drug abilify unilateral spondylolysis is important because there is a potential for full healing if the athletic activity is modified, whereas bilateral spondylolysis frequently leads to established nonunion. Maternity exclusion in disability plans continues to be major legal issue.

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Although BPD was unidimensional in terms of its symptoms, BPD as a disorder showed associations with both the distress subfactor of the internalizing dimension and the externalizing dimension. Implants were inserted in contact with the periodontal ligament of root tips retained in the mandibular jaws of 7 monkeys. The utility of gammagraphy with Tc 99-labelled dimercaptosuccinic acid (DMSA) in the protocol for studying urinary infection in a 2nd-level hospital. The clinical and radiological features most helpful in defining and classifying each case are identified. The polarity defects of vasa mutants appear to be caused by a reduction in the amount of Gurken protein at stages of oogenesis critical for the establishment of polarity. Effect of methylandrostenediol (neosteron) on vascular changes occurring in experimental steroid-diabetes. The FISH generated one ELN signal in 20 metaphases read and found the presence of ELN deletion, with compatible Williams-Beuren syndrome. Furthermore, nocturnal blood pressure anafranil and alcohol interaction elevation (non-dippers) occurs more frequently in patients with nephropathy. According to these results indocyanine green angiography is useful to differentiate occult choroidal neovascularization from areas of retinal pigment epithelium atrophy. In this study, 16 corticotropic adenomas of dogs with pituitary-dependent hyperadrenocorticism were screened for mutations in the Gs alpha, H-, K-, N-ras genes and the coding region of the DNA-binding domain of the glucocorticoid receptor.

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Intramuscular preparations of antipsychotics: uses and relevance in clinical practice. Teratogenic action of hypoxia under normal atmospheric pressure. Data on the use of cancer screening tests and coverage in two age groups from a 1992 nationally representative cross-sectional survey of approximately 9,400 adults were analyzed. This study describes the exact location of alpha 6, beta 4, and alpha 6 beta 4 and that their responses in focal cerebral ischemia are relevant to astrocyte-matrix interactions. They admitted to our hospital with the symptoms of aortic dissection. A slight delay in the outgrowth of endothelial cells was noted within the first seven days in the severely defibrinogenated group, in which the fibrinogen concentration was below 0.40 gm/L. Diffuse tumor microembolism: a rare cause of a high-probability perfusion scan. beta 2 GPI was modified with the crosslinking agent, glutardialdehyde (GDA), which induced exposure of the anti-beta 2 GPI epitope at GDA:beta 2 GPI mol ratios in the range of 500-2000. Time of incubation had less effect (increases of between two- and threefold in approximately half of the geometric mean MICs), and temperature especially had little effect (the increases were no higher than twofold).

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Establishment of an in vitro assay system mimicking human immunodeficiency virus type 1-induced neural cell death and evaluation of inhibitors thereof. The long-term results were comparable, if not superior to traction, and patient comfort and mobilization were much improved. As a striking feature, one interdomain insertion comprises four KSP repeats analogous to the multi-phosphorylation repeats of neurofilament subunits H and M. For halogenated pyrimidines, however, clinically relevant numbers of ISI are generated within each cell. Proposed new bladder volume monitoring device based on impedance measurement. IgM antibodies to dsDNA and IgM antibodies to ssDNA were not correlated with renal histological features. Improving care of patients with alcohol withdrawal syndrome in a community hospital. The GA2 locus of Arabidopsis thaliana encodes ent-kaurene synthase of gibberellin biosynthesis. Both of these compounds were found to effectively inhibit the TCD-associated differentiation induced by DMSO, HMBA, and Na butyrate and to abrogate the differentiation-associated reduction in lactate accumulation due to these agents.

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