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Elavil

Elavil is used to treat depression. Compared to other antidepressants, it has a higher risk of side effects, such as weight gain and drowsiness. Elavil is a tricyclic antidepressant (TCA). It works on parts of the brain responsible for raising levels of certain chemicals, like serotonin and norepinephrine, to help improve your mood.

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Also known as: Amitriptyline

Description

Elavil (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Elavil is a prescription medicine used to treat symptoms of depression.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Elavil dosage information

Overdose

If you overdose Elavil and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Elavil overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Elavil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Elavil if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Elavil if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Elavil is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Elavil is not approved for use by anyone younger than 12 years old.

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Using RT-PCR and digestion with Hind III and BamHI, Fasciola hepatica secreted cathepsin L1 (FheCL1) cDNA was cloned into the expression vector pcDNA3.1. The sets are composed by a number of stock market indices located all over the world in five continents. A total of 197 randomly selected adults were visited at home using the European Community Respiratory Health Survey (ECRHS) II Indoor protocol. Clinical status was evaluated using the New York Heart Association (NYHA) classification, 6-min walk test, and quality-of-life score. Several methods of transformation are currently available for delivering exogenous DNA into animal and plant cells. Thoracic collateral venous channels: normal and pathologic CT findings. Patients treated with CPG or CCG from 2011 to 2014 were included in the study. The IR, however, is not as efficient as the IGF-IR in protecting mouse embryo fibroblasts from apoptosis, even when IRS-1, one of its major substrates, is over-expressed. Taken together, there is evidence that JME is associated with dysfunctions in networks linking motor and cognitive neuronal centers. A possible implication of mast cells and proteinase-activated receptor-2 (PAR-2) in FSS is also reviewed.

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CIP2A is overexpressed in non-small cell lung cancer and correlates with poor prognosis. Understanding of non-HLA polymorphisms will help elucidate the signalling aberrations involved in MS development and may help to identify novel, personalized approaches to therapy. We have evaluated the use of a discrete proportional-integral-derivative (PID) algorithm to control hyperglycemia in pediatric ICU (PICU) patients both with and without diabetes. We identified 42 men who had undergone left-sided microsurgical subinguinal varicocelectomy at our institution and had at least one semen analysis before and after surgery. The tRNA content of imidazole-treated cells, which do not synthesize hemoglobin although they undergo other changes of erythroid differentiation, decreases initially as described above, but shows no increase from day 4 to day 6. menorrhagia, heavy menstrual bleeding, abnormal uterine bleeding). Premanufactured metal augments can be placed independent of the acetabular component. The involvement of adrenergic, serotonergic and cholinergic mechanisms in the diurnal surge of plasma prolactin (Prl) secretion has been examined using ovariectomized, polyestradiol phosphate-treated (PEP) rats bearing aortic catheters.

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Value of the EEG in detecting postoperative sequelae of cerebral tumors. We used propensity-score matching to select 3 controls for each subject from this database, matched on geography of residence, age, sex, family size and type. In a previous study, we reported marked long-term (at 35-56 days) consequences of increased pulsatile hemodynamics on arterial structure and mechanics. Inhibition of proliferation of ECV304 cells by a disintegrin from Chinese green tree viper. Correction of polyuria by activation of adenylate cyclase in Brattleboro rats. Herein, we report five patients with excessive hemifacial sweating and flushing, two of whom had a syrinx. In relation to the largest AVR quartile, the adjusted relative risks of all-cause mortality were 0.93 for the smallest AVR quartile, 0.71 for the second AVR quartile, and 0.80 for the third AVR quartile.

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Vasopressin-stimulated chloride transport in transimmortalized mouse cell lines derived from the distal convoluted tubule and cortical and inner medullary collecting ducts. Increased gene expression was confirmed by collagen degradation assays and immunocytochemistry of prostaglandin 2, a product of COX2 activity. In addition heparin coating of the extracorporeal circuit was introduced. Part-per-million concentrations of atrazine have been reported in agricultural runoff. The drug inhibits keratinocyte hyperproliferation, granulocyte function and, in addition, may exert an immunosuppressive effect. Cartilage tissue engineering is still a major clinical challenge with optimisation of a suitable source of cells for cartilage repair/regeneration not yet cardizem medicine fully addressed. Enhancing radiotherapy through a greater understanding of homologous recombination.

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