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Imitrex (Sumatriptan)

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Imitrex is used to treat migraines. It helps to relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light/sound). Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications.

Other names for this medication:
Migratan, Sumatriptan, Suminat, Sumitrex

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Also known as: Sumatriptan


Sumatriptan injection is used to treat acute migraine attacks and cluster headaches in adults. Sumatriptan works in the brain to relieve the pain from migraine headaches. It belongs to the group of medicines called triptans.

Many people find that their headaches go away completely after they use sumatriptan. Other people find that their headaches are much less painful, and that they are able to go back to their normal activities even though their headaches are not completely gone. Sumatriptan often relieves other symptoms that occur together with a migraine headache, such as nausea, vomiting, sensitivity to light, and sensitivity to sound.

Sumatriptan is not an ordinary pain reliever. It will not relieve any kind of pain other than migraine headaches. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.

Sumatriptan has caused serious side effects in some people, especially in those who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using this medicine as well as its benefits.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Migraine:

Use only after a clear diagnosis of migraine has been established Oral: Initial dose: 25 mg, 50 mg, or 100 mg orally, once -If some response to first dose occurs, a second dose may be administered at least 2 hours after first dose if needed -Oral doses of 50 and 100 mg may provide greater relief than 25 mg; however, a 100 mg dose may not provide greater effect than a 50 mg dose Maximum dose: 200 mg per 24 hours Intranasal: Nasal spray: Initial dose: 5 mg, 10 mg, or 20 mg into one nostril, once -Administer the 5 and 20 mg doses as a single spray in 1 nostril; the 10 mg dose may be administered as 5 mg into each nostril -If some response to first dose occurs, a second dose may be administered at least 2 hours after first dose if needed Maximum dose: 40 mg per 24 hours Comments: -Treatment should be started at the first sign of a migraine headache, or associated symptoms such as nausea, vomiting, or photophobia; this drug should not be used for migraine prophylaxis. -Higher doses may have a greater effect, but also carry a greater risk of adverse reactions. -The safety of treating an average of more than 4 headaches in a 30 day period has not been established. Use: For the acute treatment of migraine with or without aura.

Detailed Imitrex dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include tremors, skin redness in your arms or legs, weakness, loss of coordination, breathing problems, blue-colored lips or fingernails, vision problems, or a seizure (convulsions).


Store at room temperature between 2 and 30 degrees C (36 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Imitrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use sumatriptan within 24 hours before or after using another migraine headache medicine, including:

sumatriptan tablets or nasal spray, almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, zolmitriptan; or ergot medicine such as dihydroergotamine, ergotamine, ergonovine, or methylergonovine.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.


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