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Mazetol (Acetazolamide)

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Mazetol is used to prevent and reduce the symptoms of altitude sickness. This medication can decrease headache, tiredness, nausea, dizziness, and shortness of breath that can occur when you climb quickly to high altitudes.

Other names for this medication:
Abzole, Aceact, Acetamide, Acetamin, Acetariv, Acetazolamide, Actamid, Actamide, Actazid, Antilep, Axytex, Carbadac, Iopar, Mazetol, Mezapin, Synomax, Tegrital, Zolamide

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Also known as: Acetazolamide


Mazetol reduces the activity of a protein in your body called carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body.

Mazetol is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.

Mazetol is also used as a diuretic ("water pill") in people with congestive heart failure, to reduce the build-up of fluid in the body. This build-up is called edema.

Mazetol is also used to treat certain types of seizures, and to treat or prevent altitude sickness.


Mazetol is available in tablets. The dosage depends on the disease and its prescribed treatmen. Glaucoma treatment: 250 mg to 1 gram per 24 hours in 2 or more smaller doses. In secondary glaucoma and before surgery in acute congestive (closed-angle) glaucoma, the usual dosage is 250 mg every 4 hours or, in some cases, 250 mg twice a day. Epilepsy treatment: The daily dosage is 8 to 30 mg per 2.2 pounds of body weight in 2 or more doses. Typical dosage may range from 375 to 1,000 mg per day. Congestive Heart Failure treatment: The usual dosage is 250 mg to 375 mg per day or 5 mg per 2.2 pounds of body weight, taken in the morning. Mazetol can be used by children. If you want to achieve most effective results do not stop taking Mazetol suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Mazetol if you are allergic to it, or if you have:

severe liver disease, or cirrhosis; severe kidney disease; an electrolyte imbalance (such as acidosis or low levels of potassium or sodium in your blood); adrenal gland failure; or an allergy to sulfa drugs.

To make sure Mazetol is safe for you, tell your doctor if you have:

severe breathing problems; angle closure glaucoma; or if you also take aspirin in high doses.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Acetazolamide can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Mazetol is not approved for use by anyone younger than 18 years old.

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