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Mezapin (Acetazolamide)

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Mezapin is the only carbonic anhydrase inhibitor with significant diuretic effects. It is readily absorbed and undergoes renal elimination by tubular secretion. Its administration is ordinarily marked by a brisk alkaline diuresis.

Other names for this medication:
Abzole, Aceact, Acetamide, Acetamin, Acetariv, Acetazolamide, Actamid, Actamide, Actazid, Antilep, Axytex, Carbadac, Iopar, Mazetol, Mezapin, Synomax, Tegrital, Zolamide

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Also known as: Acetazolamide


Mezapin reduces the activity of a protein in your body called carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body.

Mezapin is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.

Mezapin is also used as a diuretic ("water pill") in people with congestive heart failure, to reduce the build-up of fluid in the body. This build-up is called edema.

Mezapin is also used to treat certain types of seizures, and to treat or prevent altitude sickness.


Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use Mezapin Sequels in larger or smaller amounts or for longer than recommended.

Your dose of this medicine will depend on the condition you are treating. If you take Mezapin Sequels for congestive heart failure, your doctor may tell you to skip your medication for a day. Follow your doctor's dosing instructions very carefully.

Take this medicine with a full glass of water.

While using Mezapin Sequels, you may need frequent blood tests.

Mezapin Sequels may be only part of a complete treatment program that may also include other medications. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Mezapin Sequels dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Mezapin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Mezapin Sequels if you are allergic to it, or if you have:

severe liver disease, or cirrhosis; severe kidney disease; an electrolyte imbalance (such as acidosis or low levels of potassium or sodium in your blood); adrenal gland failure; or an allergy to sulfa drugs.

To make sure Mezapin Sequels is safe for you, tell your doctor if you have:

severe breathing problems; angle closure glaucoma; or if you also take aspirin in high doses.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Acetazolamide can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Mezapin Sequels is not approved for use by anyone younger than 18 years old.

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