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Nolvadex (Tamoxifen)
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Nolvadex

Nolvadex is a type of hormonal therapy known as a selective estrogen receptor modulator (SERM). The drug attaches to hormone receptors (specific proteins) in breast cancer cells. Once the medication is inside the cells, it stops the cancer from accessing the hormones they need to multiply and grow.

Other names for this medication:
Caditam, Mamofen, Oncomox, Oncotam, Tamodex, Tamoxifen, Tamtero, Tevafen, Tomifen, Valodex, Xifen

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Also known as: Tamoxifen

Description

Nolvadex target is the treatment of breast cancer. Nolvadex is also taken to decrease the risk of breast cancer development, especially in women after surgery and radiation due to DCIS (ductal carcinoma in situ). Sometimes Nolvadex is taken to produce female ovulation and to treat McCune-Albright syndrome. Nolvadex is acting by blocking effect of female hormone called estrogen. It is antiestrogen. Nolvadex is also known as Tamoxifen, Blastofen, Istubal, Valodex, Soltamox, Genox, Tamofen.

Dosage

This section provides information on the proper use of a number of products that contain tamoxifen. It may not be specific to Nolvadex. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not take it for a longer time than your doctor ordered.

Medicines used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Shake the oral liquid well before each use. Measure the medicine with a marked medicine cup. The average household teaspoon may not hold the right amount of liquid.

Swallow the tablets whole with a glass of water. Do not break, divide, crush, or chew it. You can take the tablets with or without food.

Tamoxifen sometimes causes mild nausea and vomiting. However, it may have to be taken for several weeks or months to be effective. Even if you begin to feel ill, do not stop using this medicine without first checking with your doctor. Ask your health care professional for ways to lessen these effects.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (solution, tablets): For breast cancer: Adults—20 to 40 milligrams (mg) per day. Doses greater than 20 mg are given as 2 divided doses per day (morning and evening). Children—Use and dose must be determined by your doctor. For breast cancer as additional treatment: Adults—20 milligrams (mg) per day for 5 to 10 years. Children—Use and dose must be determined by your doctor. For reducing the risk of developing breast cancer in high-risk women: Adults—20 milligrams (mg) per day for 5 years. Children—Use and dose must be determined by your doctor. For reducing the risk of developing invasive breast cancer in women with ductal carcinoma in situ: Adults—20 milligrams (mg) per day for 5 years. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Nolvadex and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Nolvadex overdosage: uncontrolled body shaking, unsteadiness, problems with walking, convulsions, lightheadedness, exaggerated reflexes, problems with breathing, tremor.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Nolvadex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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