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Thorazine (Chlorpromazine)

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Thorazine, potent synthetic tranquilizing drug that acts selectively upon the higher centres in the brain as a depressant of the central nervous system. It is used in the treatment of persons with psychotic disorders.

Other names for this medication:
Chlorpromazine, Clozine, Megatil, Serectil

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Also known as: Chlorpromazine


Generic Thorazine is an effective preparation developed by medical scientists to treat certain mental or mood disorders (eg, schizophrenia), the manic phase of manic-depressive disorder and severe behavioral problems in children. Generic Thorazine is also used to control nausea and vomiting, nervousness before surgery, and hiccups that will not go away. Generic Thorazine can be used to treat episodes of porphyria and in combination with other medicines to treat tetanus. Generic Thorazine is an anti-psychotic medication in a group of drugs called phenothiazines. Generic Thorazine works by changing the actions of chemicals in your brain. Generic Thorazine may also be used for other purposes. Generic name of Generic Thorazine is Chlorpromazine. Brand name of Generic Thorazine is Thorazine.


Take Generic Thorazine by mouth with a glass of water. Take Generic Thorazine at regular intervals. Do not take it more often than directed. Do not take Generic Thorazine in large amounts. If you want to achieve most effective results do not stop using Generic Thorazine suddenly.


If you overdose Generic Mellaril and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Thorazine overdose: dry mouth, constipation, bloating or stomach cramps, feeling restless or agitated, fever, seizure, muscle stiffness, jerky muscle movements, changes in heart rate, extreme drowsiness, and fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Thorazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Thorazine if you are allergic to Generic Thorazine components, or other phenothiazines such as fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Adgan, Pentazine, Phenergan), thioridazine (Mellaril), or trifluoperazine (Stelazine). Do not take Generic Thorazine if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not use Generic Thorazine in psychotic conditions related to dementia. Do not use Generic Thorazine if you have brain damage, bone marrow depression, or are also using large amounts of alcohol or medicines that make you sleepy. Be very careful with Generic Thorazine if you have liver or kidney disease, heart disease or high blood pressure, glaucoma, severe breathing problems, past or present breast cancer, low levels of calcium in your blood, adrenal gland tumor, enlarged prostate or urination problems, a history of seizures, Parkinson's disease. Do not take Generic Thorazine together with: atropine (Atreza, Sal-Tropine); lithium (Eskalith, Lithobid); phenytoin (Dilantin); an antibiotic; birth control pills or hormone replacement estrogens; blood pressure medication; a blood thinner such as warfarin (Coumadin, Jantoven); certain asthma medications or bronchodilators; incontinence medications; insulin or diabetes medications you take by mouth; medication for nausea, vomiting, or motion sickness; medications to treat or prevent malaria; medications used for general anesthesia; medicines used to prevent organ transplant rejection; numbing medicine such as lidocaine or Novocain; a stimulant or ADHD medication; ulcer or irritable bowel medications; or medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor (prolactinoma). Avoid temperature extremes, such as saunas, hot tubs, or very hot or cold baths or showers. Dress warmly in cold weather. Avoid using other medicines that make you sleepy while using Generic Thorazine. Be careful if you drive or do anything that requires you to be awake and alert while using Generic Thorazine. Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Avoid drinking alcohol. It can be dangerous to stop Generic Thorazine taking suddenly.

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Collectively, these data show that PCho correlates with, and may promote, the maturation of NTHI biofilms. Interestingly enough, no change in anchorage-dependent growth was observed in these cells, and tumorigenic signals were controlled selectively in both positive and negative directions. The ability to strongly exploit the original potential of such nano-objects and access their properties relies on the ability to bridge the gap between the nanoscopic and mesoscopic scale. Chlordane contamination in selected estuarine and coastal marine finfish and shellfish of New Jersey, USA. We used in vitro systems, organ cultures, and dispersed testicular cell cultures, which allow the development of fetal and neonatal germ cells (gonocytes) and Leydig cells.

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The striking disparities between policies for metamizole made us try to determine if there were reasons to ban, limit or liberalize its utilization. Acetone/water extracts contained between 3.2 and 25.9 g CT/100g of extract, had CT with mean degrees of polymerisation of 2.9 to 13.3, procyanidin/prodelphinidin ratios of 1.6/98.4 to 100/0 and cis/trans flavan-3-ol ratios of 17.7/82.3 to 97.3/2.7. Although there is a considerable increase in intracompartmental pressures during and immediately after anterolateral percutaneous bridge plating of comminuted tibial fractures, intraoperative prophylactic fasciotomy is not routinely needed. Case report: pulmonary vein stenosis following RF ablation of paroxysmal atrial fibrillation: successful treatment with balloon dilation. Private madhouses made a significant contribution to the development of psychiatric practices in eighteenth-century England. The mean decimal acuity of each patient was recorded at baseline, Day 1, and Weeks 1 and 6. End structure and neuropeptide immunoreactivity of axons in sciatic neuromas following nerve section in neonatal rats.

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It has been proposed that the auxin-binding protein, ABP1, or a related protein could be involved in the first step of auxin perception at the plasma membrane. Appreciation of the complementary nature of T-cell- and antibody-based immunotherapy stimulated interest in developing approaches that combine their advantages and minimize their limitations. Characterization of an IgG monoclonal antibody targeted to both tissue cyst and sporocyst walls of Toxoplasma gondii. Improvement of early diagnosis and non-pharmacological management of AjD-A would contribute to limit risks of benzodiazepine overuse, particularly in primary care settings. Adaptive remodeling of bone--change of radius shape after resection of ulna in dog. Long-term ambulatory treatment is an attractive alternative to surgery in such patients if the family can cope with the injections and dietary regimens.

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Treatments for chronic stuttering in adults can control stuttering by teaching the speaker to use a new speech pattern. Large trials have established the role of CRT in reducing heart failure hospitalisations and improving symptoms, left ventricular (LV) function and mortality. Gastroenterology has emerged from paediatrics as a separate discipline after 1978, due to the development of basic sciences, i.e., biochemistry, immunology, pathomorphology and introduction of miniaturized endoscopic and radiological equipment. Allene Functionalized Azobenzene Linker Enables Rapid and Light-Responsive Peptide Macrocyclization. We have isolated a complementary cDNA coding for KBF1 and identified the DNA binding and dimerization domain of the protein. Difference in response of NK cell activity in newborns and adult to IL-2, IL-12 and IL-15. Our study validates the ischemia-reperfusion mechanism following laparoscopic surgery. However, anecdotal observations of male prairie voles (Microtus ochrogaster) suggest that castration does not reduce aggressive behavior. The present study was performed to gain insight into the decision-making process that patients go through when asked to participate in a cancer clinical trial.

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Significance of haemoglobin-S in the pathogenesis of hyperleucocytic syndromes in Nigerian patients with chronic myeloid leukaemia. Cobrahead malformation of the Amplatzer septal occluder device: an avoidable compilation of percutaneous ASD closure. Positional reproducibility of pancreatic tumors under end-exhalation breath-hold conditions using a visual feedback technique. Because multiple signaling pathways contribute to the key cellular responses important in lung biology, therapeutic strategies targeting PKCs may be more effective if combined with inhibitors of other pathways for additive or synergistic effect. Interventional Oncology is an exciting area of Interventional Radiology that represents one of the most rapidly expanding areas in the specialty.

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To prospectively investigate and monitor the response to antiandrogen treatment of bone metastases in patients with prostate cancer by using diffusion-weighted (DW) magnetic resonance (MR) imaging with the apparent diffusion coefficient (ADC) and functional diffusion maps (DMs). Echocardiography showed features of myopericarditis, mild pericardial effusion and mitral regurgitation. Various methods have been used in the treatment of trichiasis: epilation, excision, cryosurgery, thermocaustic needle, and argon laser. Cyanotic congenital heart disease with increased pulmonary blood flow. Pronounced hyperviscosity of sputum (no greater than 200 poises) appears also as a limiting factor to the mucociliary transport. Pathological adaptive responses of Schwann cells to endoplasmic reticulum stress in bortezomib-induced peripheral neuropathy.

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Due to acid microenvironment inside tumor, the anti-tumor effect of monocytes/macrophages against tumor cell was decreased, but the secretion of VEGF was gradually increased. The daunting complexity of the splicing reaction, although fascinating, has severely limited our understanding of its mechanistic details. Extended TIP(P) analogues as precursors for labeled delta-opioid receptor ligands. Culture with zinc (10(-5) and 10(-4) M) alone had a stimulatory effect on the bone protein synthesis. Whereas the decline in RMR appears to be related primarily to the loss of muscle tissue, the reason for the lower TEF in older individuals is less clear. Based on published field data from Chakdaha (India), the importance of the phases for arsenic mobility is evaluated quantitatively using models of growing complexity.

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The risk of substance use initiation and progression varied across the four participating communities and by season of the year. Scintigraphy was performed on 110 patients with primary hyperparathyroidism and no prior neck surgery. The formulation was optimized using a three-factor, three-level Box-Behnken design. CYP2D6-mediated conversion of tyramine into dopamine might be an interesting target for the development of new therapeutic strategies in AADC-deficiency. The above mentioned classification does not include the nonbacterial forms of endocarditis and enterococci often give rise to a disease intermediate between acute and subacute endocarditis. During cold, VRN1 expression increases, resulting in the repression of VRN2, which in turn allows activation of FT during long days to induce flowering.

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Therefore, assay results should always be interpreted in conjunction with clinical and epidemiologic findings. Severely diabetic rats develop basement membrane thickening but do not show the early hypertrophy uroxatral cost 10 mg , which is therefore not a necessary condition for basement membrane thickening to occur. Low molecular weight heparins inaugurated a new era in the treatment and prevention of cardiovascular pathology. UV transmission spectra and x-ray photoelectron spectroscopic measurements of the damaged optic and laser-induced photolysis of one of the adhesives used to hold the polarizer in position indicate that the degradation is most probably a result of UV photolysis of adhesive residue. A total of 78 cases esophageal surgical resection specimens were collected, expression of periostin and SNCG in esophageal cancer were detected. What is Established and What is New in Ablation of Persistent Atrial Fibrillation?. 3H-colchicine uptake by the sensitive and resistant lines has also been compared. Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice. Liquiritigenin derivatives and their hepatotoprotective activity. Opioid therapy for chronic pancreatitis: controlling aberrant use through behavioral management.

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Mortality and changes in the Mini-Mental State Examination (MMSE), the Geriatric Depression Scale (GDS-15) and the Activities of Daily Living (ADL) scores were analysed as outcomes from 88 years onwards. Pharmacogenetics initially emphasized observations of interpersonal variability, but the attention on interethnic differences soon followed. Surfactant use decreased mortality, was associated with more ventilator-free days and reduced the duration of ventilation. Effect of ascorbic acid on the growth and safe keeping of chicks. The main originality of the method is to compress for each gyrus the connectivity profiles used for the clustering without any anatomical prior information.

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Judgment of disability stages in Parkinson disease patients due to pathological tremor of index finger. We report the STM observation of single diarylethene derivatives (DD) embedded into alkylthiol self-assembled is actos generic monolayers (SAM) on Au(111). To describe our curriculum and the effect on resident performance and teaching faculty and nursing staff perceptions. Double mutations in both ParC and GyrA led to high-level quinolone resistance when ParC mutations were at S79. Fragmentation characteristics of neutral N-linked glycans using a MALDI-TOF/TOF tandem mass spectrometer.

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In the ARD patients, the Vim nucleus only showed enhanced connectivity with the globus pallidus and limbic lobe compared with the controls, and no connectivity showed correlation against the akinetic-rigidity scores. In this review, the existing studies on the link between androgens and cardiovascular disease have been analysed, with a particular focus on the gender-specific differences. Appropriate diagnostic tools are as important as clinical knowledge and skill to investigate patients for PAD. All nursing and therapy staff as minocin 50 mg well as new hires received STEPS training. State of the Art and Future Directions for Lower Limb Robotic Exoskeletons. Despite significant improvements in nitration of olefin an efficient metal-free synthesis remains elusive so far. No other congenital or anatomic abnormalities were observed in the patient, and she had no history of abdominal trauma or surgery.

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However, we demonstrated that apoptosis did not occur at the activation site, on the contrary of what has been shown after bacterial SAG activation. This new vertebrate model of adult neurogenesis is thus advancing our knowledge of the molecular cues in use for the activation of NSCs and fate of their progeny. The prognosis for this type of segmental myoclonus is excellent. The success in backbone resonance sequential assignment is fundamental to three dimensional protein structure determination via Nuclear Magnetic Resonance (NMR) spectroscopy. Nerve sparing surgery and recovery of erectile function appeared to have an independent protective effect on penile length loss at 1 year. Poplars are dominant trees to the ecosystem structure and functioning in riparian forests of North America Rivers and also to other part of the world. The role of the dingo in the rise and fall of sheep numbers is reviewed, revised data are provided on the present distribution and density of sheep and dingoes, and historical patterns of sheep distribution are used to explore the future of rangeland sheep grazing. The intermolecular self-quenching of rhodamine observed when the peptide was rhodamine-labeled, and the concentration dependence of self-quenching, supported this conclusion. A robust IOR was found that was not modulated by temporal information within a trial.

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The results showed an approximate comparability for normalized gene expression quantified using a SSMR-based qRT-PCR. The DNA from patients was genotyped at the MTHFR C677T and A1298C polymorphisms. Although otoscopy has been shown to compare favourably with results of tympanometry the actual diagnostic value of otoscopy for otitis media with effusion (OME) has not been evaluated in Nigeria. We aimed (1) to determine the concentration of group 5 major allergens in (a) pollen grains of clinically important grass species and (b) atmospheric particles (respirable and nonrespirable) and (2) to compare the atmospheric allergen load with clinical data to assess different risk factors for asthma and hay fever. Publicly available NIH funding data from 1996 to 2004 were analyzed. The recombinant virus was infectious also when an additional ORF encoding an EGFP reporter gene under the control of a second subgenomic alphavirus promoter was added. Greater microbial diversity, specific taxa and certain microbial co-occurrences at baseline and not the use of antibiotics predicted better clinical treatment outcomes. Ethanol treatment was also associated with a concentration-dependent and transient downregulation of c-myc transcripts. Measuring What Matters (MWM) for palliative care has prioritized data collection efforts for evaluating quality in clinical practice.

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Although it has been demonstrated that SIS supports bladder cell growth in vitro, and SIS-regenerated bladders are histologically and functionally indistinguishable from normal functional tissues, clinical utilization of SIS for bladder augmentation has been hampered by inconsistent preclinical results. We review theoretical models of how impaired coherence dynamics could lead to cancer as well as propose a new hypothesis based on the quantum electrodynamic theory of coherence. In addition, northern blot analysis indicated that, in rice, OsWRKY72 was inducible by polyethylene glycol (PEG), NaCl, naphthalene acetic acid (NAA), ABA and 42 degrees C, similar to its orthologue AtWRKY75 in Arabidopsis, implying that these two WRKY genes might be required for multiple physiological processes in their plants. We identified non-physician clinicians (NPCs) in 25 of 47 countries in sub-Saharan Africa, although their roles varied widely between countries. Pump-dump fluorescence spectroscopy was performed for photoactive yellow protein (PYP) at room temperature. Noxious stimuli decreased the peak heights of electroencephalographic bicoherence, an effect that was counteracted by fentanyl analgesia.

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The substrate was biosolids (activated sewage sludge) with mixed paper-mulch as the carbon base. The cardiac desmosome and arrhythmogenic cardiomyopathies: from gene to disease. The identification of antigens whose expression is associated with the cell cycle is a particularly attractive method with which to define proliferative populations in histological and cytological preparations. This suggested that the generation of the mediators was dependent on the biological potences but not the binding activities. Separation of proteins in urine by electrophoretic techniques may also be used to discriminate damage to different parts of the nephron. We tested the parent attachment scales of a new research and clinical measure, the Attachment and Clinical Issues Questionnaire (ACIQ). Selective mechanism-based inactivation of cytochromes P-450 2B1 and P-450 2B6 by a series of xanthates. None of the above extracts indicate the presence of saponins and cardiac glycosides. Genetically engineered Mengo virus vaccination of multiple captive wildlife species.

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Detection of bone marrow involvement in newly diagnosed post-transplant lymphoproliferative disorder: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography versus bone marrow biopsy. Difference in difference estimation was used to assess the effect of intervention on the maternal care utilization while controlling for socio-economic characteristics of women. Various chemicals modulate the genetic activity of BLM, producing either antimutagenic effects or enhanced genotoxicity. They were also more likely to have a discharge diagnosis related to oncology, neurology, respiratory, endocrinology and have to wait after taking flagyl to drink alcohol psychiatric complaints, compared with NFP who were more likely to present with a diagnosis related to injury or trauma. Thirty-four patients with T2DM and DMCI were scanned together with 33 patients with nondiabetic cerebral infarction (NDCI) on a 1.5-T MRI/MRS imager.

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