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Welnorm (Alprazolam)

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Welnorm is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Welnorm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Welnorm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcalm, Alpracon, Alprastan, Alprocalm, Alpron, Alpronit, Alprozam, Alsert, Altok, Anxofit, Anzilum, Anzocalm, Axizox, Azicalm, Benzolam, Dexolam, Dizeral, Eurolam, Fludep, Flumusa, Indolam, Kaprolam, Kurelam, Luzarn, Omelam, Ozolam, Pecalm, Plxna, Pralam, Proprazolam, Prosanti, Resta, Somnarest, Tenlax, Tensfree, Tranisol, Xylonite, Zallpam, Zeecam, Zeftra, Zepro, Ziety, Zolent, Zolran, Zolyde

Similar Products:
Cordarone, Eldepryl, Sumycin, Risperdal, Detrol, Caverta, Imotil, Perindox, Amlotin, Lakpam, Daonil,

Also known as: Alprazolam


Welnorm XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Welnorm XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Welnorm XR may also be used for other purposes not listed in this medication guide.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Welnorm with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Welnorm. Ask your doctor how to avoid withdrawal symptoms when you stop using Welnorm.

Keep track of the amount of medicine used from each new bottle. Welnorm is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Welnorm dosage information

Side effects

The most common side effects associated with Welnorm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Welnorm, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Welnorm is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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Intravenous iron therapy is a treatment option for iron deficient patients who are intolerant to oral iron or where oral iron is ineffective, but with possible adverse effects. We examined the effects of aging and high corticosterone levels on spatial learning, a key hippocampal function. The amount of C3d fragments on platelets gradually rose during the first 3 days of storage. Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae. Withdrawal of interferon-alpha results in prompt resolution of thrombocytopenia and hemolysis but not renal failure in hemolytic uremic syndrome caused by interferon-alpha. The high sulfation and high molecular weight properties for efficient anti-hepcidin activity suggest that heparin is involved in multiple binding sites. Current radiographic techniques that complement implant dentistry--Part I. Study of the fertilization capacity of mouse ova activated by thermal shock. Genotypes were used for linkage analysis to identify markers segregating with the disease trait. Serum fructosamine levels (first and second generation assay) were obtained.

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Characterization and standardization of tissue-simulating protoporphyrin IX optical phantoms. Since it is predominantly expressed in cells of epithelial origin (Caco-2, HeLa, MDCK), and rare (human skin, A72) or not detectable (Vero) in fibroblastic cells, we name it E-MAP-115 (epithelial MAP of 115 kD). We report the design and application of a novel PCR primer set targeting fungal p450nor, a biomarker for fungal N2O production, and demonstrate the utility of the new approach to assess fungal denitrification potential in fungal isolates and agricultural soils. Disadvantages of laparoscopic laser ovariectomy included cost of specialized equipment, need for advanced training in laser and laparoscopic surgery, and increased operative time. At times, the revision surgeon may be faced with a well-fixed component on one side of the joint and revision implants from a different manufacturer. Along with our previous results that the tyrosine phosphatase activity of Eya is dispensable for normal Eya function in eye formation, we demonstrate that a primary function of Eya during Drosophila eye development is as a transcriptional coactivator. The clinical picture can frequently be complicated with symptoms that may be misleading, and hence, challenging to assess. Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA.

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Risk factors for dysphonia and voice-specific QOL impairment were identified and might be useful for identifying patients at risk for dysphonia. To examine the role of the HGF system in epithelial invasion followed by loss of connective tissue attachment in periodontitis, mRNA expression of HGF, its receptor (c-met) and HGFA in gingival tissues was monitored. Imminent brain death and brain death are not the same: reply to Verheijde and Rady. Breast-fed infants had higher hepatic acyl CoA cholesterol acyltransferase activity and lower plasma lecithin cholesterol acyltransferase activity. In the long run, the characterization of such differences might lead to lifestyle prediction or to an evaluation of the pathogenic potential of newly isolated bacteria via the definition of genetic and/or metabolic signatures characteristic for pathogenic or symbiotic organisms. Clinical picture of influenza in young children in the epidemic of 1965 in Kiev.

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Improvement of nalbuphine bioavailability through rectal administration of a prodrug. The actin assembles into parallel bundles, and known filopodial components localize to the tip and shaft. The development of a regional EMS system for Tidewater Virginia. Because cancer is a common cause of VCP a thorough evaluation is necessary. Noncovalently functionalized multi-wall carbon nanotubes in aqueous solution using the hydrophobin HFBI and their electroanalytical application. The novel promoter PLtetO-1 allows the regulation of gene expression over an up to 5000-fold range with anhydrotetracycline (aTc) whereas with IPTG and arabinose the activity of Plac/ara-1 may be controlled 1800-fold. Human Cerebrospinal Fluid Promotes Neuronal Viability and Activity of Hippocampal Neuronal Circuits In Vitro. We conclude that, although present in cultured villous cytotrophoblasts, ROI/RNI are not induced by TNF-alpha and IFN-gamma and do not mediate cytokine-induced apoptosis. The objective of this study was to assess the prevalence, gender differences, and time trends of Sickle Cell Trait in the Southern Suburb of Beirut, Lebanon, as well as to highlight the importance of screening for Sickle Cell Trait carriers in this population. For both the chromosomal gene and the plasmid-borne promoter, mRNA accumulation is kinetically favored in the mutant relative to a wild-type isogenic strain.

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Dose dependence of vinblastine-induced autophagocytosis in liver parenchymal, exocrine pancreas and seminal vesicle epithelial cells of the mouse in vivo. Mitochondrial creatine kinase (MiCK) occurs primarily as an indocin tablets octameric form localized in the mitochondrial intermembrane compartment in vertebrate tissues and echinoderm spermatozoa (both deuterostome groups). At subsaturating concentrations, the NGF mutant was less effective than wild-type NGF in promoting the survival of embryonic sensory neurons and postnatal sympathetic neurons but was equally effective as wild-type NGF in promoting the survival of embryonic sympathetic neurons. Using a panel of these arbitrary unit polymers to detect minisatellites, we are attempting to develop paternity testing systems on pure bred dog pedigrees. The aim of this investigation was therefore to measure mast cell and eosinophil mediator levels and indices of vascular permeability in naturally occurring rhinitis. The reactivity spectrum of the isolated lymphocytes raised against cultured 78FR-G-219 cells was monitored by means of two different assays: Lymphocyte microcytotoxicity test (LMC) and colony inhibition assay (CIA). We studied a group of 69 patients consecutively transplanted and with followup of at least one year.

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Since: i) this reaction may represent the first step in the abiotic decomposition of mucohalic acids, ii) mucoxyhalic acids have been proposed as possible intermediates in the reaction of MXA with DNA, a kinetic study of the reaction mechanism is of interest. Forty-eight hours after injection, an increase in Ca-independent NOS activity was observed in the injected striatum. Knockdown of FUT3 expression in MDA PCa2b cells by small interference RNA (siRNA) significantly reduced FUT3 expression. The polytene chromosomes of bristle-forming-cells of Calliphora erythrocephala with special consideration of sex-linked structural heterozygosity and puff patterns during metamorphosis. The summary score of the QWB and various health concepts of the SF-36 respond similarly after joint replacement from osteoarthritis. We report here that exposure of M13 filaments to a chloroform-water interface at 2 degrees C trapped the phage particles in forms morphologically intermediate to filaments and spheroids. Our findings provide further evidence that non-clinical schizotypy is not associated with atypical language laterality. To test the possible interaction of polyamines in plant growth responses, transgenic tobacco plants containing the Avena sativa L.

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The impact of prior hepatitis B virus infection on liver histology and the response to interferon therapy in chronic hepatitis C. The paracrine factors and signal transduction pathways responsible for regulating ET-1 production in breast cancer are unknown. The effects of topoisomerase inhibitors on the circular form of EBV DNA during virus replication are discussed. Lifestyle factors sleep duration and media time during childhood differ between countries. The lack of cross generalization between cocaine and procaine suggests that the anesthetic properties of cocaine contribute little toward its discrimination by this mouse strain. Modification of the effects of strychnine on motor function in Rana esculenta caused by administration of serotonin. Bone cancer occurrence among beagles given 239Pu as young adults. With mucus-producing epithelium trapped within these bony confines, pressure began to mount with expansion and thinning of the bone both anteriorly and posteriorly. This diabetic subtype associates in the vast majority of cases with a single mutation in mitochondrial DNA, at position 3243. Immunohistochemical studies may help in differentiating pancreatoblastoma from papillary cystic tumors, acinar cell carcinomas and endocrine pancreatic tumors of the pancreas.

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To measure tissue glucocorticoid sensitivity in patients with septic shock and determine its relationship to standard measurements of adrenal function and of outcome. It may be more likely that risk for systemic effects is related to total injection dose and injection frequency. In addition, comparisons were made between nurses working in different hospitals and also different nursing units within a hospital. We performed a retrospective analysis of a prospectively collected database from six centers in western Pennsylvania and West Virginia. The analysis identifies six efficient programmes with cost-effectiveness estimates ranging from 17000 to 42500 Danish kroner (DKK) per life-year. Analysis of 200 consecutive neuropathologically verified brain tumors of childhood. Three experienced clinicians independently assessed the quality of the proximal contacts of all restored teeth (total of 150 contacts) relative to the 4 types of contacts exemplified by the dental study models. Intestinal and liver slices, exposed to the substrates 7-ethoxycoumarin (7-EC), 7-hydroxycoumarin (7-HC) and lidocaine (Li), exhibited similar metabolic rates in the biochip and in the well plates for periods of at least 3 h.

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Loss- and gain-of-function assays demonstrated that SPRY4-IT1 promoted cell proliferation, migration, and invasion in osteosarcoma. Differential diagnosis of tegmental lesions in neonates and infants include congenital metabolic syndromes and drug-related processes. The K650E substitution in the fibroblast growth factor receptor 3 (FGFR3) causes constitutive tyrosine kinase activity of the receptor and is associated to the lethal skeletal disorder, thanatophoric dysplasia type II (TDII). Lack of a correlation between the MAu and MM binding energies means that no correlation can also be expected between adsorption enthalpies on gold and sublimation enthalpies in groups 15 through 17. ETC insertion was successful in all 10 patients in whom it was attempted. At a low level of expression, the degradation of misfolded MalE31 was partially impaired in cells lacking DegP or Protease III.

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