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Xenical works by keeping your intestines from absorbing some of the fats from the food that you eat. The undigested fat goes out of your body in your bowel movements. This medicine is available both over-the-counter (OTC) and with your doctor's prescription.

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Also known as: Orlistat


Xenical is created by pharmacists to help people with a body mass index (BMI) greater or equal to 30 kg/m² or with BMI greater or equal to 28 kg/m² when associated risk factors to tackle obesity. The active ingredient of Xenical is Orlistat, which belongs to lipase inhibitors. It prevents absorption of some fat from the intestines, removes this fat from the body in stools thereby reducing weight gain. Note, that while taking Xenical, it is recommended to be on a nutritionally balanced, low-calorie diet that contains approximately 30% of calories from fat. Xenical is also used in overweight people who suffer from high blood pressure, high cholesterol, diabetes and in heart patients. The goal of Xenical is to help to get rid of excess fat in the body and to stop weight gain after losing weight.


Xenical is taken orally 3 times a day during the main meal or up to 1 hour after the meal. The diet of the patient should include three main meals, containing the daily dose of fat, carbohydrate, and protein. The daily intake of fat should be no more than 30% of your total daily caloric intake (e.g., eating 1200 calories per day, no more than 360 of those calories should be in the form of fat). The dose of Xenical should be omitted if a meal is missed or does not contain fat. Treatment with Xenical should not continue for more than 6 months and should be stopped after 12 weeks if patient has been unable to lose at least 5 % of the body weight. If you lose enough weight for your BMI to fall below 28 kg/m², Xenical can no longer be supplied.


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Xenical if you are allergic to orlistat, or if you have malabsorption syndrome (an inability to absorb food and nutrients properly).

You also should not use this medicine if you have:

gallbladder problems; or if you are pregnant.

Do not use alli if:

you are not overweight; you have had an organ transplant; or you use cyclosporine (to prevent organ transplant rejection).

To make sure Xenical is safe for you, tell your doctor if you have ever had:

kidney stones; gallbladder disease; pancreatitis; underactive thyroid; liver disease; kidney disease; or an eating disorder (anorexia or bulimia).

Do not use Xenical if you are pregnant. Weight loss is not recommended during pregnancy, even if you are overweight. Stop taking orlistat and tell your doctor right away if you become pregnant.

Taking orlistat can make it harder for your body to absorb certain vitamins. These vitamins are important if you are nursing a baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Xenical is not approved for use by anyone younger than 12 years old. Do not give alli to anyone under 18 years old.

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