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Zanaflex (Tizanidine)

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Zanaflex is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Zanaflex is used to treat spasticity by temporarily relaxing muscle tone.

Other names for this medication:

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Also known as: Tizanidine


Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Tizanidine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain tizanidine. It may not be specific to Zanaflex Capsule. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it and do not take it more often than your doctor ordered. To do so may increase the chance of side effects.

When you take the different dosage forms (tablets, capsules, capsule contents sprinkled over applesauce) of tizanidine with food, it affects the amount of the medicine absorbed into your blood differently. Follow your doctor's instructions for when to take this medicine and whether or not you should take it with food.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For muscle relaxation: Adults—At first, 2 milligrams (mg) every 6 to 8 hours. Your doctor may adjust your dose as needed. Do not take more than 36 mg within a 24-hour period. Children—Use and dose must be determined by your doctor.


If you overdose Generic Zanaflex and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zanaflex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Vaginal birth after cesarean: do California hospital policies follow national guidelines?. This solution is being fought by organized dentistry that sees the approach as an economic threat, but AI/AN organizations are committed to implementing this Native solution to their access problem. In addition, in saline-treated animals, growth of exercised rats was slower than that of resting rats during the day following exercise. The cooperative diffusion is a generic feature of a good solvent environment, whereas a second slow relaxation mode appears in the theta solvent regime. Erdheim para que sirve el medicamento neurontin 400 mg -Chester disease (ECD) is an uncommon, non-Langerhans form of histiocytosis, which is characterized by radiological and pathological findings, but its treatment is still controversial. We present 2 cases of intracranial mass lesions in whom remifentanil was used to obtain serial neurological examinations.

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Combination intracavitary chemotherapy for malignant pleural disease. The promising outcome in patients with good performance status and patients with gross total resections are notable. In the present review we elaborate on the role of PGPR in helping plants to cope with drought stress. Noninvasive and quantitative evaluations of the severity of isolated pulmonary valvular stenosis using two-dimensional pulsed Doppler echocardiography. Most of the ultrasonic gas flow-meters measure the gas flow rate by calculating the ultrasonic transmission time difference between the downstream and upstream. These difficulties must be weighed against the advantages of a negligible infection rate and extremely low nonunion and implant failure rates. Facial appearance persistence is high and facial appearance transfer is low after virtual face transplantation. We searched bibliographic databases and abstracts from relevant conferences from Jan 1, 2000, to March 1, 2015. The isolates from two children induced morphological changes of the viral-sensitive cell lines, such as syncythia formation (cell fusion). Abstracts of all retrieved studies were screened to include the most relevant studies and only studies which met inclusion criteria were selected.

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Lipophilicity of the pyrazole moiety, N-alkyl chain length and planarity of the two heterocyclic rings appear to play a decisive role in modulating cytotoxicity and antifungal activity. Androgen receptor (AR) expression is maintained in high-grade, undifferentiated prostate carcinoma, and thus, could be considered as a potentially useful adjunct to the conventional panel of markers. Data of 88 women form the basis of this report (45 ad libitum sodium intake and 43 dietary sodium restriction). These findings differ from what has been previously observed in healthy, aged-matched populations and confirm that cerebral arteries abnormalities, mainly involving the posterior circle, are not so rare in LOPD patients and are often accompanied by a lacunar encephalopathy that might represent a hypoxic-ischemic origin. The economic appraisal can give a range of probabilities of cost-effectiveness depending on willingness or ability to pay. Enzyme-linked immunosorbent assay (ELISA) for the identification of mosquito bloodmeals. Under the national antimalaria programme DDT was introduced in early 1950s for vector control and later hexachloro cyclohexane (HCH) followed by malathion and recently synthetic pyrethroids in 1990s to manage the insecticide resistance in Anopheles culicifacies. In this study, faecal samples were obtained regularly from 14 infants from 1 month to 18 months of age.

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Observational cohort study of consecutive community-dwelling elderly individuals previously hospitalised in medical or surgical wards and of volunteers residing in nursing homes or assisted-living facilities. The results of assessment using the Hamilton Rating Scale for Depression, the Leeds Self-Rating Scale for Depression and the Clinical Global Impressions severity scale showed that both therapies were effective in resolving depression in the patients studied. Identification of murine CBF alpha1, a runt domain transcription factor, as a putative Myc collaborator in T cell lymphoma. Thus, the relationship of OT responsivity to BP in 14 breast- and 11 bottle-feeding mothers of infants was examined. The size of native aorta in Asians, which shall affect the definition of AAA, has also never been reported. The categorical transformation is a more flexible way to explore the unknown shape of the dose of norfloxacin in child effect between an explanatory and a dependent variable. Thirty-year-old woman with lower abdominal pain was operated due to adnexial mass.

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